Adding nitric oxide to membrane lung (through the swwp gas flow) in children on #ECMO, before-after study including 🔍 393 #ECLS runs: 49% received NO
Just out on @asaiojournal#PedsICU
🖇️ https://t.co/vPjvJ3hZrE
Adding NO to the SGF to ML in children on #ECMO??
🖇️ https://t.co/BH6bqhoECG
📦 use of NO associated with 37% ⬇️ in circuit change
🧠 link between NO & lower risk of neurologic injury in children who underwent cardiac surgery observed
⚖️ no difference in survival between study groups
Given theoretical benefits associated with NO (such as preventing PLT adhesion to surfaces, mitigating inflammatory response, protection against I/R injury) & observed benefits in this study, NO therapy warrants on ECMO warrants prospective evaluation in #PedsICU. @asaiojournal
Amy’s story about water safety is one that every parent needs to hear.
Stay safe around water this summer and learn the facts at https://t.co/hk6K16LsOU
📽️ https://t.co/VDy0maUeCB
💉 Vancomycin + pip–tazo associated with ⬆️risk of creatinine-defined #AKI in critically ill: pseudotoxicity?? No changes in alternative kidney function biomarkers, nor downstream clinical outcomes associated with true AKI (dialysis/mortality).
#FOAMcc
📎 https://t.co/p14pevw6UE
@ExpensiveScare Considering both these treatments are non standard for Bronch in AU this raises many Qs. Esp if just those on high flow benefit.
So should all infants who need high flow have this Rx?
@PEMDocSyd A bigger ward based study perhaps needed to assess, but it’ll potentially make big waves in the management of the sickest; the primary outcome was adjusted for resp support at baseline and it *halved* the duration of positive pressure in those on CPAP and mechanical ventilation!
Combined dexamethasone and nebulised adrenaline reduces duration of respiratory support in PICU patients! Congratulations @BenGelbarttwitr@RCHMelbourne@MCRI_for_kids for the DAB trial; pragmatic RCT in paediatric ICU patients admitted with bronchiolitis: https://t.co/fW2aUDEaiM
@BenGelbarttwitr You know, I think I just might… lots to discuss. Do we *need* a bigger study? (Will we have equipoise?) Future studies in patients on High flow nasal prongs on wards? Hard to know how generalisable, recognising the inclusions and exclusions in this pragmatic RCT. Well done!
Very sad to announcing the passing of A/Prof Andrew Hilton. A loving & caring husband & father. An irreplaceable, compassionate and brilliant clinician. A tireless voluntary worker for CICM.
Simple, step-by-step video guide to master ultrasound guided vascular access from Royal Children’s Hospital, Melbourne. Aim for first pass success, every time. Long cannula allows majority of cannula *in* the vessel = max longevity and min complication. https://t.co/DLAHLyT5BE
Flexible nasoendoscopy to examine the nasal septum, turbinates, nasopharynx, soft palate, base of tongue and larynx. It’s a simple, well tolerated procedure that would give a lot of useful information.
“Intensive care isn’t designed for massive peaks like that.”
Intensive care doctor Stephen Warrilow explains why #Covid19 treatments are so challenging for hospitals. More @business : https://t.co/nweS8zbDBG
A flexible nasoendoscopy is a routine procedure I perform on many patients daily as part of a complete ENT examination. If you’re interested in seeing my nasal turbinates, nasopharynx and larynx, catch this 2 minute video of me doing it to myself.