Felix Scholkmann

Researcher/Lecturer@UZH_ch | Neurophotonics, functional neuroimaging, integrative human physiology, biophysics, signal processing, physics, philosophy and more

[Felix Scholkmann @FScholkmann]

@MitoPsychoBio There might be a link to mitochondria ... https://t.co/CevIWl5HGE

[Felix Scholkmann @FScholkmann]

New paper:
𝐄𝐫𝐲𝐭𝐡𝐫𝐨𝐜𝐲𝐭𝐞𝐬 𝐚𝐬 𝐚𝐜𝐭𝐢𝐯𝐞 𝐫𝐞𝐠𝐮𝐥𝐚𝐭𝐨𝐫𝐬 𝐨𝐟 𝐛𝐥𝐨𝐨𝐝 𝐟𝐥𝐨𝐰:
𝐀 𝐛𝐫𝐢𝐞𝐟 𝐨𝐯𝐞𝐫𝐯𝐢𝐞𝐰
Red blood cells are more than just oxygen carriers ...
https://t.co/LbT24UK7Xv
PDF: https://t.co/mjgqJKJ9Jr

[Felix Scholkmann @FScholkmann]

@bryan_johnson This reminds me of when I suffered from chemical pneumonia due to air pollution after New Year's fireworks (2016 in Stuttgart, Germany) ... https://t.co/QiaGhoHPtm

[Felix Scholkmann @FScholkmann]

https://t.co/6FHYXViy3N
PDF: https://t.co/EPBGW8ewhS
#biophysics #mitochondria

[Felix Scholkmann @FScholkmann]

Our new paper:
𝐄𝐱𝐭𝐫𝐚-𝐦𝐢𝐭𝐨𝐜𝐡𝐨𝐧𝐝𝐫𝐢𝐚𝐥 𝐀𝐓𝐏 𝐬𝐲𝐧𝐭𝐡𝐞𝐬𝐢𝐬, 𝐩𝐫𝐨𝐭𝐨𝐧 𝐝𝐲𝐧𝐚𝐦𝐢𝐜𝐬 𝐚𝐭 𝐭𝐡��� 𝐦𝐞𝐦𝐛𝐫𝐚𝐧𝐞 & 𝐦𝐢𝐭𝐨𝐜𝐡𝐨𝐧𝐝𝐫𝐢𝐚-𝐝𝐞𝐫𝐢𝐯𝐞𝐝 𝐯𝐞𝐬𝐢𝐜𝐥𝐞𝐬: 𝐂𝐮𝐫𝐫𝐞𝐧𝐭 𝐟𝐢𝐧𝐝𝐢𝐧𝐠𝐬 𝐚𝐧𝐝 𝐜𝐨𝐧𝐬𝐢𝐝𝐞𝐫𝐚𝐭𝐢𝐨𝐧𝐬
@annsaada

[Alexander von Lühmann @avolu_neurotech]

🚀Cedalion v25.1.0 is out! Open-source #Python toolbox for #fNIRS & #DOT with new support for #parcel-based analysis, #multimodal #ML, #imagerecon, synthetic data #augmentation & more. Docs + Colab + GitHub: https://t.co/M3MHiXCU5N.🔧Huge thanks to all contributors!

[Felix Scholkmann @FScholkmann]

‘Luminous Links: Encounters with Light in Science, Society, and the Senses’
Nice event @ Collegium Helveticum (ETH/UZH)

I gave an overview of my fNIRS research, biological autoluminescence & that intense light experiences can be encountered during altered states of consciousness

[Felix Scholkmann @FScholkmann]

Lymphatic vessels can contain a vessel inside (primo vessel)!
https://t.co/r0ND86xiQQ
New publication together with colleagues from Seoul National University
• The primo vessel is part of the primo vascular system and differs from a blood or lymph vessel
#anatomy

[Felix Scholkmann @FScholkmann]

@BANTonline https://t.co/r0ND86xiQQ
Scholkmann, F., Shen, Y. & Ryu, P.-D. (2025). Microscopic analysis of a primo vessel within a lymphatic vessel in a Sprague-Dawley rat. Translational Research in Anatomy, 39, 100402

[Felix Scholkmann @FScholkmann]

Lymphatic vessels can contain a vessel inside (primo vessel)!
https://t.co/r0ND86xiQQ
New publication together with colleagues from Seoul National University
• The primo vessel is part of the primo vascular system and differs from a blood or lymph vessel
#anatomy

[Felix Scholkmann @FScholkmann]

The glutamate/GABA-glutamine cycle: Insights, updates & advances
https://t.co/02XRod6GWV
Nice review by J.V. Andersen.
The glutamate/GABA-glutamine cycle is essential to maintain synaptic signaling & brain function

[Felix Scholkmann @FScholkmann]

@memcculloch @annsaada 2-3 nm (thickness of the major dense line)

[Felix Scholkmann @FScholkmann]

Myelin: A possible proton capacitor for energy storage during sleep & energy supply during wakefulness
https://t.co/hi8QQ0sdRr
New publication together with A.M. Morelli & A. Saada (@annsaada)
• A new hypothesis as to why living organisms need sleep
#neuroscience #biophysics

[Felix Scholkmann @FScholkmann]

Myelin: A possible proton capacitor for energy storage during sleep & energy supply during wakefulness
https://t.co/hi8QQ0sdRr
New publication together with A.M. Morelli & A. Saada (@annsaada)
• A new hypothesis as to why living organisms need sleep
#neuroscience #biophysics

[Felix Scholkmann @FScholkmann]

@real_JackKruse Our theory is valid for all living organisms with a brain. Brain metabolism involves mitochondrial OXPHOS. Mitochondria are found in the cells of nearly every eukaryotic organisms. Myelin and myelin-like sheaths are found in animals with brains.

[Felix Scholkmann @FScholkmann]

@annsaada Myelin (rich in lipids) also seems to be an oxygen buffer - see our book chapter from 2023: https://t.co/w3UHBvipOl
Myelin therefore appears to be a proton capacitor, oxygen buffer & site of extramitochondrial OSPHOS. This topic has been extensively studied by Prof. Morelli

[Felix Scholkmann @FScholkmann]

@akatzzzzz @annsaada Indeed, there are many implications for medicine and therapy - for example in multiple sclerosis, see our paper from 2023: https://t.co/56JX97s2Lo

[Felix Scholkmann @FScholkmann]

@DrJackKruse And also relevant to this discussion: our paper from 2021 -> Myelin sheath and cyanobacterial thylakoids as concentric multilamellar structures with similar bioenergetic properties https://t.co/Oo0fn791Hc

[Felix Scholkmann @FScholkmann]

@DrJackKruse The fact that there are animals that don't have myelin (some invertebrates) and do sleep does not contradict our hypothesis. In these animals, a similar biophysical process could be at work forf example in the myelin-like glial cell wrapping around the axons.

[Felix Scholkmann @FScholkmann]

@annsaada And in our opinion, the standard model of cellular energy metabolism also needs to be reconsidered.
The new approach is: glucose metabolism is coupled to the pentose phosphate pathway & extra-mitochondrial OXPHOS (especially at the endoplasmic reticulum)
https://t.co/fH0Txu4P0O