🔥WHO published its 1st global research agenda for the world’s scientists to address the most urgent human health priorities to combat antimicrobial resistance
It outlines 40 research topics on drug-resistant bacteria,fungi& Mycobacterium TB
H/t @paimadhu
https://t.co/AOVObnJK5Q
The MERCY trial of prolonged vs intermittent meropenem has been published, with a neutral (i.e. no difference) outcome on the primary measure. So is that it for prolonged infusions of antibiotics, can we just go back to intermittent dosing? 🧵(TL:DR no)
https://t.co/qZSOxDMqTq
TDM of antimicrobials in #ICU
💉life-saving drugs, difficult pharmacology
💉TDM: why do we need it?
💉uncertainties
concentrations to be targeted/where
adjusting dose if out of range
steady state: prerequisite?
outcomes when studying TDM
#FOAMcc
🖇️ https://t.co/0DiDW7ONvV
💉 Dexmedetomidine sedation in adults on MV in #ICU, rapid practice guideline: use suggested over other agents, if desirable effects including ⬇️ #delirium valued vs undesirable, including ⬆️ hypotension & bradycardia - weak recommendation (suggestion).
📎 https://t.co/H6FwEfew2i
🔥🔥 Today, @esicm is launching the #AIRSPACE webapp - a tool to support #antibiotic decisionmaking at the bedside in the #ICU
https://t.co/HM0KauhtxM
Honoured to have been leading this with @DrMCecconi and immensely grateful to everyone who contributed (1/x)
The Intensive Care Platform Trial (INCEPT) research programme aims to prepare, initiate and run an adaptive platform trial assessing commonly used interventions in acutely ill intensive care unit (ICU) patients. Follow this account and https://t.co/6BLGMKepcB for updates!
Jeg stiller i dag et simpelt spørgsmål via @Altingetdk. Det er ikke let at besvare for den enkelte eller for samfundet, men det er nødvendigt at stille. Det er nødvendigt at tage de svære beslutninger når der er tid til det, når det ikke er akut. https://t.co/XmUKr4d17h
Don't forget to check out the On-Demand recordings of the #LIVES2021 meeting #VOD
Hours of high-quality presentations available for you!!
👉 https://t.co/VTDPNiefUw
Our pole among Swedes show that around 80% are positive to participate in research even though they can not sign informed consent. Next of kin is prefered choice to act as legal representative. #ESICM, #ICUresearch, #IntensiveCare, #CriticalCare
https://t.co/Pt47fo14Ig
Trump's latest bout of gaslighting scientists has pushed the NEJM editors to explicitly recommend leadership change. unprecedented but appropriate. #BidenHarris2020
Varför ska inte Sverige vara med och bidra till att förbättra vården och behandling för IVA-patienter? Det är dags att även vi har möjlighet att solidariskt delta i forskningen för denna grupp.
”Feltolkning stoppar studier på medvetslösa” https://t.co/U1qNsa67rG via @SvD
#music thought of the day: A jazz guitarist plays 100,000 chords and makes 3 people happy. A rock guitarist plays 3 chords and makes 100,000 people happy.
The largest ICU trial in the world began today in Wellington - the study of liberal versus conservative oxygen therapy. More information here:
https://t.co/2aqh49cx9I
#MegaROXtrial