Fangjia Zhu

DNA origami technique in plasmonics

[Guillermo Acuna Lab @GuilleAcuna_Lab]

Do you remember our previous work on controlling the position and orientation of single emitters? 🚀 We’ve taken it to the next level! 1/5 @ACSPhotonics https://t.co/FfFSIWq1me

[Guillermo Acuna Lab @GuilleAcuna_Lab]

We have open positions for PhD and Post-doc researchers in my group to work on Nanophotonics and DNA nanotechnology for sensing. I paste here the flyer with more information.

[Guillermo Acuna Lab @GuilleAcuna_Lab]

I want to congratulate @FangjiaZ for his outstanding thesis defense. Also a very special moment for me as Fangjia is my first student to graduate. It was a pleasure to work with you.

[Guillermo Acuna Lab @GuilleAcuna_Lab]

Warming up with some drinks with our visitor William Shih from @harvardmed @wyssinstitute @DanaFarber before his Seminar at @UnifrPhysics @NCCRbioinspired

[Guillermo Acuna Lab @GuilleAcuna_Lab]

How to direct the light from single photon sources? Check our latest publication https://t.co/VuImlPXSTS in collaboration with the Nanoplasmonics group lead by Prof. Jer-Shing Huang @Leibniz_IPHT 1/3

[Guillermo Acuna Lab @GuilleAcuna_Lab]

Our work “DNA Origami Assembled Nanoantennas for Manipulating Single-Molecule Spectral Emission” carried out by María Sanz Paz, @FangjiaZ, Nicolas Bruder, Karol Kołątaj, led by @aifernand and @Guille_P_Acuna has just been published in Nano Letters. https://t.co/8nJUwAuoZ7 1/6

[Amelie Heuer-Jungemann @Amelie_HJ]

⬇️⬇️⬇️Amazing opportunity for a PhD position!

[Guillermo Acuna Lab @GuilleAcuna_Lab]

In particular, we study how different parameters such as the shape of the plasmonic nanorods, possible defects in the dimer assembly, and different positions and orientations of the emitter can affect the directionality. https://t.co/G4849W40m4. 2/3

[Guillermo Acuna Lab @GuilleAcuna_Lab]

Very nice work done by @FangjiaZ , María Sanz Paz, @Pilopais in collaboration with @aifernand . @MDPIOpenAccess https://t.co/QRayQsd1lH. 3/3

[Nano Letters @NanoLetters]

@ACSPublications Editors' Choice free for a limited time "DNA-Templated Ultracompact Optical Antennas for Unidirectional Single-Molecule Emission" @FangjiaZ, Sanz-Paz, Fernández-Domínguez, Zhuo, @LizMarzan_Lab @FerStefaniLab, Pilo-Pais, & @GuilleAcuna_Lab https://t.co/utwKXYckwy

[Fernando Stefani Lab @FerStefaniLab]

Do you have a confocal microscope in your lab? Then you can perform 1-nm single-molecule localizations in it with only a few modifications. We present #RASTMIN, an alternative to #MINFLUX that can be easily implemented in existing confocal setups. 1/6
https://t.co/s3z1lAFFte

[Fernando Stefani Lab @FerStefaniLab]

Congratulations to @l_masu, @SzalaiAlan, @luhalac1 and our collaborators @Pilopais and @GuilleAcuna_Lab for the beautiful work! 6/6

[Fernando Stefani Lab @FerStefaniLab]

Combining #RASTMIN with ON/OFF stochastic blinking we performed proof-of-principle nanoscopy experiments by imaging DNA origamis with 2-nm precision using only N ~ 2000. 4/6

[Fernando Stefani Lab @FerStefaniLab]

In this way, we raster scan over the region of interests with a doughnut-shaped beam. The image of the single-molecule that we produce is basically a dark spot, making the localization extremely photon-efficient. 3/6

[Fernando Stefani Lab @FerStefaniLab]

For #RASTMIN, we only made two modifications to our beam-scanning confocal microscope: we added a Vortex Phase Plate (VPP) in the excitation path and a cost-effective active stabilization system. 2/6

[Guillermo Acuna Lab @GuilleAcuna_Lab]

Many thanks to our collaborators, Antonio Fernandez Dominguez, @LizMarzan_Lab and Xiaolu Zhuo. Funding and support @snsf_ch, @NCCRbioinspired, @agenciaidiar, @unifr and @UnifrPhysics, @CONICETDialoga, @CONICETDialoga and @NanoLetters for the Editor´s choice 8/8.

[Guillermo Acuna Lab @GuilleAcuna_Lab]

Also, using the unique advantages of DNA origami we could show that when one rod is missing, or the fluorophore is placed equidistant from the two rods, unidirectionality is lost and a symmetric 2 lobe pattern is detected.7/8

[Guillermo Acuna Lab @GuilleAcuna_Lab]

Interested in nanophotonics? We present ultra-compact optical antennas based on gold nanorods capable of directing the emission of single fluorophores. Theoretically predicted more than a decade ago and finally realized thanks to the DNA Origami technique! https://t.co/r4xjw54zoX