Fasan Lab

At @UTDallasChemBio, we design & develop novel chemo-biosynthetic and chemo-enzymatic strategies for the discovery of biologically active molecules

[Fasan Lab @FasanLab]

Delighted to share our paper just appeared in Chemical Science on the discovery of macrocyclic peptides targeted against an RNA motif from SARS-CoV-2! Congrats to Jake, Andrew, and Abhijith @UT_Dallas
and great collab with Wedeking group @URochester_SMD
https://t.co/MfqdrT1C6f

[Fasan Lab @FasanLab]

Congrats to newly minted Dr. Bo Couture for earning his PhD degree in Chemistry @UTDallasChemBio !!👏 Bo has developed new biocatalytic strategies for stereoselective C(sp3)-H functionalization via carbene transfer. Congrats Bo and best luck with your career in pharma!

[Fasan Lab @FasanLab]

Our best congratulations to our Andrew (now Dr. Andrew Hong) for defending his PhD thesis with flying colors this week! 🎉 🎉 Andrew will now return to the U Rochester Medical Center for resuming his medical training toward his MD/PhD degree. PhD#20 from the Fasan group!

[Fasan Lab @FasanLab]

Congrats to our Ron, now Dr. Adukure, for defending his PhD thesis today! 🎉 🎉 Very proud of you and your accomplishments 👏 and wish you continued success for the next step in your career!

[Fasan Lab @FasanLab]

Honoring the exceptional women in the @FasanLab at @UT_Dallas whose insight, dedication, and curiosity elevate our work every day! Happy International Day of Women and Girls in Science to Anwita, Francesca, Michelle, Pamela, Ru, Shreya, Sophie, and Zoe! 🎉

[Fasan Lab @FasanLab]

A great visit by Prof. Yi Lu at UT Austin as our departmental seminar speaker this past week! We really enjoyed hearing about his group's exciting work in the design of artificial enzymes and DNA-based sensors for diagnostics. Inspiring science and great discussion!

[Fasan Lab @FasanLab]

Delighted to share our publication in @NatureComms on the computational design of generalist carbene transferases with tailored, stereodivergent selectivity! Great collab with Sagar Khare! Kudos to Zhuofan, Mary, and Xinkun and all other coauthors!
https://t.co/YAtfzLI0np

[Angewandte Chemie @angew_chem]

@FasanLab @UT_Dallas develops a new powerful method for skeletal editing of complex natural products at aliphatic C-H sites by combining site-selective and tunable enzymatic hydroxylation with chemical oxidation/ring expansion. Read on: • https://t.co/M9mOBLlcRL

[Fasan Lab @FasanLab]

Very grateful to Benjamin List and Kateryna Kryvous for selecting our paper on a photobiocatalytic strategy for C(sp3)-H acylation for a highlight in Synfacts!
🙏 🙏
https://t.co/yZDkcw2AYL

[Fasan Lab @FasanLab]

Check out our paper just published in @angew_chem on a chemoenzymatic strategy for ‘skeletal editing’ of complex molecules with engineered P450s! Big congrats to John Bennett, Andrew Bortz, Zheyuan Wang, & Muhammed Fastheem for the excellent work!
https://t.co/pntFf2Cvvd

[Fasan Lab @FasanLab]

Congratulations to @Yining_Wang_ in the @FasanLab at @UT_Dallas for passing his qualifying exam! He is now officially a PhD candidate! Way to go, Yining! 👏👏

[Ambika Bhagi-Damodaran @AmbikaBhagi]

📢📢Our lab has a #postdoc opening!! If you are interested in pursuing *exciting* research at the interface of biocatalysis, cellular signaling, structural biology, and computation chemistry, reach out to me at [email protected]. Check out our recent work: https://t.co/vtUb1RaZz3

[Fasan Lab @FasanLab]

Kudos to our Clark summer research fellows Gianna Eckerle and Andy (Anh Triet) Tran for doing a great job at presenting their research projects at the SURP Symposium @UT_Dallas!

[Fasan Lab @FasanLab]

Check out our paper on stereoselective synthesis of halogenated cyclopropanes via biocatalytic cyclopropanation! Kudos to lab members Ron Adukure and Muhammed Fastheem and big thanks to our collab Tay Rosenthal, Matt Robinson & team at Corteva Agriscience!
https://t.co/LP4z1N7dOy

[Fasan Lab @FasanLab]

We are hiring! Multiple postdoctoral positions are available in our lab in the areas of biocatalysis, protein engineering/design, and peptide/protein therapeutics: https://t.co/eN4eAZVgs3 Interested candidates should email the PI with CV and cover letter. Please spread the word!

[Fasan Lab @FasanLab]

Photobiocatalytic Enantioselective Benzylic C(sp3)–H Acylation Enabled by Thiamine-Dependent Enzymes via Intermolecular Hydrogen Atom Transfer | Journal of the American Chemical Society https://t.co/nbmw1tgecP

[Fasan Lab @FasanLab]

On the International Day of Women and Girls in Science, a big shoutout to all the women in the @FasanLab @UTDallasChemBio for their outstanding contributions to our science! Go Aanu, Anwita, Elanor, Francesca, Hiram, Mary, Marriah, Michelle, Pamela, Ru, Shreya, and Yashika!🦾🎉

[Fasan Lab @FasanLab]

Congrats to Jadab @majhijadab , Saty, and Anwita @Anwita_Ch for their recent paper in @ACSCatalysis on a new biocatalytic strategy for the asymmetric synthesis of oxazolidinones via intramolecular C-H amination with engineered myoglobins! Great job! 🎉👏
https://t.co/gBwM44CDxF

[Fasan Lab @FasanLab]

Happy to share our recent paper on the regiodivergent C(sp3)–H functionalization of indolines via enzymatic carbene transfer in @ChemCatalysis Big kudos to lead authors Bo Couture and Ru Cui for the excellent work!🎉 https://t.co/dYvhVL9eoC

[Fasan Lab @FasanLab]

We are hiring! Our Department of Chemistry and Biochemistry at @UT_Dallas has two open-rank faculty positions in the areas of Biochemistry and Inorganic Chemistry, broadly defined. Come join a dynamic and vibrant department!
https://t.co/VmIefVAmko
https://t.co/R6p3QJ9l4s