Ferdinand Greiss

Exploring rules of nature with synthetic systems and multiple scales at the Weizmann Institute. Preferences for single molecules.

[Ferdinand Greiss @FeSchiessl]

stretching chromosomes, mapping their DNA/protein organization, running cell-free gene expression directly on them, and dissecting non-eq vs eq compaction. Chromosomes can show a lot when put in cell-like compartments. let me know what you think.

https://t.co/Ieffdy314z

[Weizmann Institute @WeizmannScience]

Can a pandemic be stopped before it even begins? A new tool developed by Weizmann's researchers could help prepare us for the next viral threat >> https://t.co/OrHzENhj5o

[Joshua Ricouvier @jricou]

My latest article is out! 1000 artificial cells synchronize in 2D and collective behavior emerges!
#microfluidics #artificialcells #syntheticcells #cellfreeexpression
https://t.co/rR520tMmrE

[Matthaeus Schwarz-Schilling @matthschwa]

I would like to share our pre-print. Autonomous biogenesis of the entire protein translation machinery excluding ribosomes https://t.co/0dUEXEzng9

[Ferdinand Greiss @FeSchiessl]

While writing these posts, I remembered my initial ideas probably already 3-4 years back (😅). I sketched my first scientific animation, put it aside, and forgot about it. The details changed, of course, but I hope you can still see the connection and enjoy my debut as animator.

[Ferdinand Greiss @FeSchiessl]

Latest preprint on transplanting chromosomes into microfluidic biochips and rebooting the genome with cell-free gene expression. The deconstruction into a simple artificial system revealed fascinating DNA swelling dynamics with transcription. Enjoy!

https://t.co/SexMRWkn3Z

[Ferdinand Greiss @FeSchiessl]

And here is a small teaser for some (but certainly not all) of the tech development required to reconstitute chromosomes with steady-state gene expression.

[Aurore Dupin @AuroreDupin_90]

I'm thrilled to share the preprint of our latest work on antibody profiling using a cell-free multiplex platform.

Cell-free immuno-profiling on a genetically programmed biochip https://t.co/GldoWnVFta

[Weizmann Institute @WeizmannScience]

Researchers at Weizmann Institute observed, for the first time, a protein being born from a single DNA molecule outside a cell. This breakthrough led them to develop the smallest-ever genetic circuit, paving the way for future nano-biotech applications >> https://t.co/Xr1pj1yOjl

[Synthetic Cell initiative @SynCellEU]

Check out our new post!
With German and American colleagues, #RoyBarZiv's team has identified and characterised a gene regulation mechanism that could be used in the design of synthetic cells to optimise resources and functions
@WeizmannScience @FeSchiessl
https://t.co/ukYVTDpZhP

[Phys.org @physorg_com]

Beyond cells: Unveiling the potential of genetic circuits on single DNA molecules @NatureComms https://t.co/Yi1cWnUUuz

[Ferdinand Greiss @FeSchiessl]

And now officially available with @NatureComms at https://t.co/QgrXOM9S9a. Thanks to all X-having authors @NicolasLardon, @thenoireauxlab, and X-less authors!

[Ferdinand Greiss @FeSchiessl]

Observing genetically encoded proteins emerging one by one from single DNA molecules. I am happy to share new techniques, findings about the basics of coupled transcription and translation, and genetic circuits without a cell.

https://t.co/7HaOuncdkL

[Joshua Ricouvier @jricou]

Large scale integration of artificial cells in a microfluidic chip !! prepublished on bioRxiv
https://t.co/oDTc5mJElS

[Ferdinand Greiss @FeSchiessl]

@OlivierDuss That’s exciting! We recently also found gene regulation of proteins when produced locally on single DNA by the expressome (https://t.co/PY0MFkZnTG). Would be nice to combine these methods…

[青木 航 / Wataru Aoki @mighty_tora]

Very excited to share our latest preprint! We finally achieved the reconstitution of ribosome self-replication outside a living cell. (1/9)
https://t.co/7T6tzIq8Lb

[てら @teratera_ttt]

イノシシかよ

[Richard C Schneider @richardcschneider.bsky.social @rc_schneider]

A little sign of hope and sanity: Jews and Arabs demonstrating together: https://t.co/H97v9d76lZ

[openUC2 @OpenUc2]

Cubes, cubes cubes!📦Do you want to have TheBOX or a handy microscope?🔬How many #openUC2 cubes does the world need?🌍 Help us to find out by filling out our Demand Survey: https://t.co/63VcmZjHEJ
Please retweet! 💚
#openhardware #opensource #OpenEducation

[Henrike Niederholtmeyer @HNiederho]

Want to use creative approaches to construct new biological systems from scratch? My lab has an open PhD position on engineering synthetic compartments in cell-free reactions. https://t.co/uXTrpDjLxI Please retweet!