Using optogenetics to activate a subset of neurons in the medulla provokes anxious behavior in mice, a study in @NeuroCellPress shows.
By Sarah Thau
https://t.co/21mE7HvZzt
thrilled to share our latest work from the lab, led by the amazing @Fernandezpa_C (now a PI at @unmc!) where we found a new role for a tiny group of adrenergic neurons in RVLM, the C1 cells. https://t.co/WzOKcVyweo
Estamos haciendo todo lo posible para mantener ritmo de fabricación de ortesis, férulas, e inmovilizadores para donar. Nos pueden ayudar con un like o un RT.
🚨New preprint alert🚨
We used closed-loop optogenetics to causally test the importance of inhibitory spike timing in network function and found that manipulating PV+ cell theta phase locking in the dentate gyrus can shift seizure susceptibility (both ways!)
I am thrilled to share that I will be starting my laboratory in the Department of Neurological Sciences @UNMC_neurology at the University of Nebraska Medical Center @unmc as an Assistant Professor!
I am deeply grateful to my family, colleagues, collaborators, and mentors,
its role in psychiatric disorders. By leveraging a wide array of
novel neurophysiological and genetic approaches, we aim to help in the development of more efficacious therapies.
We will be publishing available positions at the postdoc and technician levels soon; so stay tuned!
especially Rosa Señarís and @lindsayschwarz, for their invaluable support and encouragement in this journey to achieve this milestone!
The Fernández-Peña Lab will seek to advance our understanding of the neurobiological mechanisms underlying interoception and
🎄PinkyCaMP- our christmas gift to you! 🎁: We are excited to present PinkyCaMP, the first mScarlet based calcium sensor with:
✨exceptional, brightness
✨phototability
✨and optogenetic compatability.
Check out our new preprint:
https://t.co/nekymls09X
Discover our new TRISCO method, which enables 3D RNA analysis at cellular resolution in intact brains. Explore a 3D rendering that reveals the deep brain expression pattern of the Parvalbumin gene, implicated in schizophrenia.
@ScienceMagazine.
https://t.co/tqysZ36zRz
Such sophisticated studies presented by these young speakers💯👏🏽We learned that NPY calms the LC, C1 adrenaline make anxiety exacerbate LC stress responses, female LC responds more than males to a stressor, pupil dilation is also affected by serotonin, & abt prediction and smell!
New preprint from the Schwarz lab!🥳 Led by the extremely talented postdoc @Fernandezpa_C (who is on the job market this year💪). Carlos used complex intersectional strategies to functionally characterize a brainstem circuit involving C1 adrenergic neurons.
🥳Excited to share our new paper in its final form: https://t.co/9C3kfBt8Fj. If your research would benefit from intersectional tools (a way to target cells based on multiple features), then ConVERGD might be of interest. Doesn't need to be 🧠-related!