Frohlich Lab

Revolutionize psychiatry. Rational design of 🧠 stimulation. Change the 🌎! PI: @flaviofrohlich Own opinion.

[Flavio Frohlich PhD @FlavioFrohlich]

@FrohlichLab @NeuroStimCtr I write about the neuroscience of being fully human: brain rhythms, mental health, embodiment, and what it actually takes to thrive.
Follow @FlavioFrohlich if that's the conversation you want more of.

[Flavio Frohlich PhD @FlavioFrohlich]

@FrohlichLab @NeuroStimCtr You are not a processor running on meat.
You are a rhythmic, relational, embodied being whose brain evolved for connection, movement, and meaning ... not optimization!
Act accordingly.

[Flavio Frohlich PhD @FlavioFrohlich]

We are more than biological LLMs.
AI processes tokens. You process life through a body that breathes, moves, aches, and desires.
We've built a culture that celebrates the brain and shames everything below the neck.
For many of us, this is a deep source of pain and confusion.
🧵

[Flavio Frohlich PhD @FlavioFrohlich]

🧠🧵 THREAD: What acetylcholine & norepinephrine teach us about learning, growth, and change

This year, the @FrohlichLab turns 15. 🎉

Over that time, we’ve published 100+ papers on brain dynamics, neuromodulation, and neurotechnology.

In this thread, I want to offer something different:

👉 a fresh, unifying, and slightly provocative perspective, starting with our first paper

Here’s what we learned ↓

[Brain Stimulation @brainstimj]

New in Brain Stimulation! @SteinAthena & colleagues introduce tECS - transcranial endogenous current stimulation, using personalized EEG-derived waveforms to target aperiodic brain activity. A novel approach in neuromodulation.
https://t.co/0Ro7ExXJsW

[Flavio Frohlich PhD @FlavioFrohlich]

Fifteen years after demonstrating the power of low-amplitude endogenous electric fields on a neural network in a dish, I am excited to introduce tECS - fabulous work with star postdoc @SteinAthena in the @FrohlichLab @UNCPsychiatry - huge thank you to @BBRFoundation

[Athena Stein PhD MPH @SteinAthena]

@BBRFoundation @FrohlichLab @NeuroStimCtr @UNCPsychiatry @brainstimj tECS builds on foundational cortical slice electrophysiology by @FlavioFrohlich showing that weak endogenous electric fields can entrain neural activity.

Thank you to @BBRFoundation for making this possible. Also grateful to @_aaausa for supporting my time in the US!

[Athena Stein PhD MPH @SteinAthena]

Excited to share our latest publication introducing a new class of brain stimulation: transcranial endogenous current stimulation (tECS) ⚡️

Supported by @BBRFoundation

@FrohlichLab @NeuroStimCtr @UNCPsychiatry @brainstimj

[Frohlich Lab @FrohlichLab]

Introducing transcranial endogenous current stimulation (#tECS) - pioneered at the Carolina Center for Neurostimulation @UNCPsychiatry, published @brainstimj

Built on foundational work by @FlavioFrohlich in 2010: https://t.co/e28nPxnAhc

Thank you @BBRFoundation!
@SteinAthena

[Flavio Frohlich PhD @FlavioFrohlich]

Fifteen years after demonstrating the power of low-amplitude endogenous electric fields on a neural network in a dish, I am excited to introduce tECS - fabulous work with star postdoc @SteinAthena in the @FrohlichLab @UNCPsychiatry - huge thank you to @BBRFoundation

[Frohlich Lab @FrohlichLab]

We are excited to share these cool results from @GraceRoss98 's dissertation. Lots of implications for targeting networks of cognitive control with rhythmic brain stimulation. Make sure to follow @GraceRoss98 as she has more good stuff in the pipeline!

[Grace Ross @GraceRoss98]

‼️Excited to share that our newest paper from the @FrohlichLab is now published!!

This paper includes results from my dissertation work, suggesting that frontoparietal theta synchrony is a promising therapeutic target for attention disorders.

🧵1/6

https://t.co/FCxS4CdLNQ

[Flavio Frohlich PhD @FlavioFrohlich]

Leading up to my 15 year anniversary at UNC next year, I decided to share with you our scientific journey from neuronal mechanisms to novel treatments in the @FrohlichLab

[Athena Stein PhD MPH @SteinAthena]

Inside the brain and ready to spark some new connections - come chat with me about brain network changes following #tACS treatment in #MDD at poster # F150 this afternoon at #SOBP2025!

@NeuroStimCtr
@FrohlichLab

[Frohlich Lab @FrohlichLab]

Research Participants wanted! We’re recruiting for our study “Inter-brain Synchronization of the Therapist-Client Dyad in Psychotherapy: Pilot EEG Study in Students with Mild to Moderate Depression Symptoms” UNC IRB#: 22-1422, P.I: Flavio Frohlich, PhD. If you’re interested, please check out the flyer and complete the pre-screen to see if you’re eligible.

[Flavio Frohlich PhD @FlavioFrohlich]

Excited to have three clinical trials for depression and anxiety in our @NeuroStimCtr @UNCPsychiatry currently enrolling participants. https://t.co/NGMlcw956X

[Frohlich Lab @FrohlichLab]

Alpha/theta state dynamics!

[Frohlich Lab @FrohlichLab]

It is happening right now - our very own @GraceRoss98 defending her PhD thesis. Awesome work with big translational implications for non-pharmacological treatments of attention challenges. @NeuroStimCtr

[Flavio Frohlich PhD @FlavioFrohlich]

Check out this update on our recent work at the @NeuroStimCtr @FrohlichLab @UNCPsychiatry https://t.co/5OPjk8EeyP

[Frohlich Lab @FrohlichLab]

Thank you @MarkZylka Follow us over at @NeuroStimCtr to learn about upcoming clinical trials of non-invasive 🧠 stimulation. We will be posting updates and recruitment info. @UNCPsychiatry

[Mark Zylka @MarkZylka]

Outstanding! Two UNC Neurosci Center faculty (Eva Anton and @FrohlichLab) as well as a UNC Perl prize recipient (@doristsao).

[Grace Ross @GraceRoss98]

Huge news!!! Congratulations to @FlavioFrohlich and everyone in our lab @FrohlichLab for this amazing accomplishment!

[UNC School of Medicine @UNC_SOM]

For years, the @FrohlichLab has been developing and tweaking an innovative brain stimulation device that can help treat depression and anxiety.

Now, after clinical trials and support from the @FDA, the device is one step closer to patient use.
https://t.co/HDdEez9XxQ