KarlssonLab@LU

The Stem Cell and Leukemia Lab @Lund_Stem @lunduniversity. Focus on normal- and malignant hemtopoietic stem cells and single-cell genomics.

[Lund Stem Cell Center @Lund_Stem]

🚀🧫Exciting start to our 2024 #StemCellTalk series at @MedFak_lu! Assoc. Prof. Göran Karlsson discussed 'Exposing the #stemcells of Chronic Myeloid Leukemia' and their therapy resistance, offering new perspectives.

More on @GKarlssonLab's research ⤵️
https://t.co/gTqF2UARht

[KarlssonLab@LU @GKarlssonLab]

Some stem cell markers indicate ongoing hematopoietic output. The latest work from our lab;
CD9 marks myeloid/MegE-biased human hematopoiesis https://t.co/UQ6KuWTqsL

[KarlssonLab@LU @GKarlssonLab]

#MyOAarticle "Scarf enables a highly memory-efficient analysis of large-scale single-cell genomics data" received 5,567 downloads since its publication! Access the article here https://t.co/zzOrhBNJwD

[KarlssonLab@LU @GKarlssonLab]

This study also for the first time shows that Leukemic stem cells and healthy stem cells residing in a patient’s bone marrow can be distinctly separated by two surface markers 🎯 🚀. Read our article to learn how these discoveries can revolutionize CML treatment! 📚🌟

[KarlssonLab@LU @GKarlssonLab]

📢 The latest work from our group (more in comments)! #CML #TKI #LeukemiaResearch #CellularHeterogeneity #TreatmentResponse #CITEseq #SingleCellGenomics https://t.co/23NmOR63jO

[KarlssonLab@LU @GKarlssonLab]

A groundbreaking study on how the stem cell heterogeneity of chronic myeloid leukemia (CML) patients at diagnosis effects the response to tyrosine kinase inhibitors (TKIs). 🧬🔬

[KarlssonLab@LU @GKarlssonLab]

Congratulations to Fatemeh Mojgan Safi for brilliantly defending her thesis on HSC lineage priming and CD9 @Lund_Stem! Great discussion with opponent Kim Theilgaard-Mönch. #science #research #PhD #thesisdefense #LundStemCellCenter

[KarlssonLab@LU @GKarlssonLab]

Presenting at the fantastic Danish single-cell meeting

[Tune H. Pers @tunepers]

Systematically mapping enhancers in hematopoietic stem and progenitor cells👍

Göran Karlsson @GKarlssonLab Lund University @lunduniversity @Lund_Stem #singlecellCPH23

https://t.co/zc2dP5vWl9

[KarlssonLab@LU @GKarlssonLab]

The lab is very proud of Dr Parashar Dhapola who brilliantly defended his thesis today. Thanks to Kostya Khodosevich @KhodosevichLab for being an excellent faculty opponent! Congrats @ParasharDhapola!

[Lund Stem Cell Center @Lund_Stem]

🧣Now in @NatureComms, Scarf, a novel memory-efficient solution for single-cell genomic #analysis created by @lunduniversity & @Lund_Stem researchers: @ParasharDhapola & @GKarlssonLab

Discover how it can help scientists navigate their #genomics data ⤵️

https://t.co/AzbaFm1pKb

[KarlssonLab@LU @GKarlssonLab]

The latest work from our lab by @ParasharDhapola and colleagues!Scarf is a memory efficient tool for single-cell genomic analysis with important applications. https://t.co/rHsy8iQHyg

[KarlssonLab@LU @GKarlssonLab]

@CellReports @Bo_Porse Nice work Matilda, Bo et al!

[Lund Stem Cell Center @Lund_Stem]

New findings from the @GKarlssonLab at @lunduniversity illuminate an elusive cell state during the development of normal #blood #stemcells🩸🔦

Read about their work which sheds light on how properties of these cells are lost as they decide their fate👉 https://t.co/6qzF5tUEPH

[KarlssonLab@LU @GKarlssonLab]

https://t.co/CkfffYOava

[KarlssonLab@LU @GKarlssonLab]

So very proud of the team behind our latest study characterizing hematopoietic stem cells before they make a decision on what lineage to become. https://t.co/5xRpCkPQcs

[KarlssonLab@LU @GKarlssonLab]

So proud of Mikael Sommarin for receiving his PhD yesterday! 🍾🎓Thanks David Kent @scienceadvocacy for a brilliant discussion!

[Parashar Dhapola @ParasharDhapola]

Just released Scarf 0.18.0🚀

Many improvements for handling snATAC-Seq datasets. Check out the updated vignette here:
https://t.co/yjRuy7wF1F

#singlecell #snATACseq #genomics

[Cristian Bellodi @BellodiCristian]

Really excited to share our latest work that links spliceosomal RNA modifications to selective control of alternative splicing and redox homeostasis in cancer cells https://t.co/poCIY9HrKG. Huge congrats to our Giulia @GiuliBeneventi and all the other co-authors!

[Boiers Lab @BoiersLab]

Happy to see our protocol paper in STAR Protocols published on line. Thank you all co-authors for a great collaboration!

In vitro differentiation of human pluripotent stem cells into the B li... https://t.co/OMZVOcz000

[KarlssonLab@LU @GKarlssonLab]

Minireview from our lab and our friends in @BoiersLab on the power of single-cell heterogeneity analysis for understanding developmental hematopoiesis. https://t.co/VPD3mhNdlx