GPCR_ucph

G protein-coupled receptors; molecular pharmacology; translational science; University of Copenhagen; lab of Prof. Mette M. Rosenkilde

[GPCR_ucph @GPCR_ucph]

@demet_arac @szym_ko @birlamirla Congratulations! Looking forward to reading this.

[Viktoria M S Kjær @ViktoriaKjaer]

In addition, we locate another entrance connecting the #GPCR binding site to the extracellular milieu and link it to the activation by less hydrophobic synthetic agonists https://t.co/Jc5E5TEfND.
Once again @t00mek88 delivers the impressive graphics.

[Viktoria M S Kjær @ViktoriaKjaer]

Our new work describing how #GPCR GPR183 utilizes a lateral entry facing the membrane to recognize its endogenous #oxysterol ligand https://t.co/QS6cmE41eV. Now out in @ChemicalScience.
@t00mek88 @JanaSelent @MM_Rosenkilde

[GPCR_ucph @GPCR_ucph]

Congrats Lærke. Looking so much forward to follow your research.

[Lærke Smidt Gasbjerg @GasbjergL]

This is AMAZING! 😀 Looking forward to exploring more physiological effects and therapeutic potentials of our gut hormones 👩‍🔬at @BiomedUCPH @Rigshospitalet @UCPH_health @GPCR_ucph
- now supported by @novonordiskfond

[Science Signaling @scisignal]

Cell experiments unveil how a potential therapeutic target coordinates cell migration, bioluminescent sensors reveal how molecules called WNTs bend a receptor-effector complex, and more in this week’s issue of #ScienceSignaling. https://t.co/H03lbRmyGE

[GPCR_ucph @GPCR_ucph]

New publication by @ViktoriaKjaer and @MM_Rosenkilde in @scisignal this week.

[Viktoria M S Kjær @ViktoriaKjaer]

📰Publication announcement📰
This week in Science Signaling we show that #GPCR #GPR183 internalizes independently of #arrestin, but rather utilizes a mechanism involving #caveolin. Arrestins, though, are crucial for migration mediated through the receptor. https://t.co/GhcXdXNNAq

[Lærke Smidt Gasbjerg @GasbjergL]

Important to celebrate 🥳 Today we complete study day 50 (of 80) in the MRI basement at @Rigshospitalet studying GIP+GLP-2 in gut blood flow #alwayschocolate @UCPH_BRIDGE @GPCR_ucph @BiomedUCPH

[GPCR_ucph @GPCR_ucph]

Monday Morning Meeting in the sunny fall of Copenhagen ☕️🥐😎@MM_Rosenkilde @BiomedUCPH

[GPCR_ucph @GPCR_ucph]

Discussing incretins and their receptors at European Incretin Study Group Meeting in Lausanne these days 📷BenJones @MM_Rosenkilde @GasbjergL #tirzepatide #GPCR

[Jacek Mokrosiński @jmokrosinski]

Long-awaited #4GPCRnet meeting kick-off! 4 days packed with exciting talks, poster presentations and, last but not least, live networking of the GPCR community that we all missed for the last couple of years. Thank you @ErnestNetwork @ca18240 @sfb142, #FOR2372, and @UniLeipzig!

[GPCR_ucph @GPCR_ucph]

DDA Summer School is SO hilarious! Four girls from @GPCR_ucph attend in high spirits #DDA_Education #DanishDiabetesAcademy @DDA_Denmark 📷: @MadsHelsted

[GPCR_ucph @GPCR_ucph]

Congratulations to Ludvig Schimming Langberg for finishing his master thesis project within gut hormones and their action on intestinal blood flow. Supervised by Lærke Gasbjerg. A learning experience in translational research. Great teamwork by two rising stars. I’m so proud!

[GPCR_ucph @GPCR_ucph]

Congratulations to Lærke Gasbjerg for her graduation from team 2 of the Bridge programme. Two years of great translational research within gut hormones’ action on intestinal blood supply with a vision of novel therapeutic potential in this system.

[Peter Lindquist @Plindquist_ucph]

Thanks to all co-authors for a great collaboration: @GasbjergL , @jmokrosinski , Jens Juul Holst, @alexshauser , and @MM_Rosenkilde

[Peter Lindquist @Plindquist_ucph]

Here we elucidate the spectrum of naturally occurring mutations in the intestinal hormone, glucose-dependent insulinotropic polypeptide (GIP), involved in blood glucose homeostasis and bone remodeling #GPCR #GIP

[Peter Lindquist @Plindquist_ucph]

Happy to share that our latest study, "The location of missense variants in the human GIP gene is indicative for natural selection" has been published in @FrontEndocrinol.

Full article (open access): https://t.co/msSi5pOGWB

[Lærke Smidt Gasbjerg @GasbjergL]

Great to spend Saturday afternoon with the Danish Diabetes Association @DiabetesDK and recent and previous grant recipients @aWegeberg @linehjort 🌺🏆 // thanks for the support! #GPCR #GIP @GPCR_ucph

[John Janetzko @jjanetzko]

@GPCR_ucph @lab_tall He teased about a tethered peptide mechanism huh. So are you saying he dangled the idea out there before ya’ll eventually picked up on it?

[GPCR_ucph @GPCR_ucph]

Exciting talk by Prof. Kimberley Tolias about the role of Rho GTPase signaling for BAI1 biology. Unfortunately the last talk of our nice workshop! Enjoy the sushi! #adhesionGPCR2022

[GPCR_ucph @GPCR_ucph]

Thanks to Dr. Rory Morgan for another interesting zebrafish talk about defining small-molecule modulators of Gpr126 mediating Schwann cell myelination #adhesionGPCR2022