GPCRdb

GPCRdb contains data, diagrams and web tools for G protein-coupled receptors (GPCRs).

[GPCRdb @gpcrdb]

Database developer staff scientist positions (5-year) open now (https://t.co/7FetqN2Owt). Join our great team to build tomorrow’s online research data/tool infrastructure enabling science and drug design for GPCR drug targets and their signaling proteins. #programming

[GPCRdb @gpcrdb]

New online data and tool resources for basic research and #drugdesign on #GPCR and signaling proteins funded by Infrastructure grant from @novonordiskfond. Keep an eye out for GPCRdb, GproteinDb, ArrestinDb and BiasedSignalingAtlas and new databases. #DataScience @DrGPCR

[GPCRdb @gpcrdb]

June update of https://t.co/ecFhBDjnP6 is here! Visit the site to see what's new! #GPCR #GPCRdb

[GPCRdb @gpcrdb]

The new https://t.co/ecFhBDjVEE 2023 March update is online! Check out all the new data and features #GPCR

[GPCRdb @gpcrdb]

Biased Signaling Atlas preprint is out https://t.co/sbqlOaOqGX describing the birth of a new database dedicated to biased signaling, may let #GPCR drugs favor therapeutic over adverse signal pathways.

[GPCRdb @gpcrdb]

GPCRdb 2023 with state-specific structure models using AlphaFold2 and new ligand resources is now online (https://t.co/hwTRLexENK). Thanks to the team, #GPCR community, @NAR_Open, @lundbeckfonden and @novonordiskfond.

[GPCRdb @gpcrdb]

New publication in eLife shows how different datasets were integrated in the common coupling map in GproteinDb. https://t.co/mUXp51WeBP and https://t.co/o7Lte90lK3

[David Gloriam @David_Gloriam]

Proud to share our article “Common coupling map advances #GPCR - G protein selectivity” as a final pdf in eLife. https://t.co/fYcdtHdcm8 It integrates datasets from the @Michel_Bouvier and Asuka Inoue labs, and the @GuidetoPHARM database to arrive at several new insights.

[GPCRdb @gpcrdb]

The new Biased Signaling resource in GPCRdb will act as a hub for reporting biased ligands while supporting these community guidelines.

[David Gloriam @David_Gloriam]

Finally, much-needed community guidelines for #GPCR ligand bias! Can better experiment design and reporting clarify complex pharmacology towards #drugdiscovery with fewer adverse effects? https://t.co/i07205Pc0C

[GPCRdb @gpcrdb]

Open position for a research assistant or postdoc in bioinformatics / database development.
https://t.co/WYwak1TnzZ
#GPCR @pharmacogenomics @DatabaseDev

[David Gloriam @David_Gloriam]

Big congratulations to Albert Kooistra, lead developer of GPCRdb, for receiving the Frank Blaney Award from the Molecular Graphics and Modelling Society! https://t.co/tfpLBs9vkc #GPCR https://t.co/n3KLuuFytH

[GPCRdb @gpcrdb]

GPCRdb structure analysis resource out in NSMB.

[David Gloriam @David_Gloriam]

Proud sharing cover page and two back-to-back articles in @NatureSMB describing a new structure analysis platform revealing #gpcr activation mechanisms across classes and macro/microscales. https://t.co/3I95GGVX1Q and https://t.co/FhTf2fpwEW

[GPCRdb @gpcrdb]

Proud to present the publication of GproteinDb dedicated to G protein research and sister database of GPCRdb (). Thanks to the team, #GPCR community, @lundbeckfonden, @novonordiskfond, and @DFF_raad. https://t.co/3Lk7zLaRAp

[GPCRdb @gpcrdb]

Check out the new GPCRdb resources in our webinar on June 24th at @DrGPCR https://t.co/bMJhnldqz3. Thanks to @yaminaberchiche. #gpcr

[GPCRmd @GPCRmd]

Temporary free access here https://t.co/87ZGzDeKNL :)

[GPCRmd @GPCRmd]

Excited to share our new review, Structural dynamics bridge the gap between the genetic and functional levels of GPCRs
https://t.co/zUP4ZR1ifE .
Great work @David_Gloriam @JanaSelent @MarionaTf @t00mek88 !

@ErnestNetwork @GPCR_ECC @j0kaso @gpcrdb @DisGeNET

[David Gloriam @David_Gloriam]

In two pre-prints we present a new structure analysis platform uncovering #gpcr activation mechanisms across classes and macro/microscales. & https://t.co/eMPwwMBTSB #structures https://t.co/Pw43ocpixT

[GPCRdb @gpcrdb]

Head of GPCRdb, David Gloriam shares his story as a #gpcr scientist and inspiring young researchers in a podcast @DrGPCR https://t.co/oH0cfhBveo. Thanks to @YaminaBerchiche and #drgpcr

[GPCRdb @gpcrdb]

The GPCRdb 2021 version integrating sequence, structure and function is now online in Nucleic Acids Research (https://t.co/iuv6guXpQg). Thanks to the team, #GPCR community, @lundbeckfonden and @novonordiskfond.

[GPCRdb @gpcrdb]

Class D1 nomenclature and alignments now in GPCRdb.

[David Gloriam @David_Gloriam]

Nature article https://t.co/uqGVK1hRYM of class D #GPCR structure, Ste2 dimer coupled to two G proteins from Chris Tate lab @MRC_LMB and adding @GPCRdb resources. Thanks to @VaidehiLab, @DFF_raad, @lundbeckfonden & @novonordiskfond. https://t.co/vKWI2Ylc4K https://t.co/Rec54mRTV3

[GPCRdb @gpcrdb]

Nature article https://t.co/lHPFHHcpZD showing #GPCR isoform signalling bias, and a GPCRdb resource https://t.co/5FQMrhod0y. Another landmark study from @m_madan_babu group and great teamwork by Marti-Solano et al. Thanks to @Lundbeckfonden and @novonordiskfond