Gal Oren

Scientific Computing and AI Researcher @ Technion & Stanford

[Gal Oren @GalOren8]

What if a general LLM could become a biological instrument with the right fine-tuning? In @PNASNews, we present ADAR-GPT: a #GPT model trained step-by-step that learns ADAR targeting grammar, generalizes to new Alu sequences, and captures key constraints from the sequence alone.

[Gal Oren @GalOren8]

@katiekirsch 💫

[Gal Oren @GalOren8]

@embirico @OpenAI https://t.co/1KgO4eAETk took about 2 months end to end

[Michael Levitt @MLevitt_NP2013]

@GalOren8 @PNASNews So happy to see my two favorite fields, RNA and Machine Learning, converging in this just published paper in PNAS. @GalOren8

[Gal Oren @GalOren8]

@OpenAIDevs @OpenAI
@OpenAINewsroom

[Gal Oren @GalOren8]

#Codex for #HPC? We put it in the toughest arena: parallel code across heterogeneous hardware. Built a hardware-in-the-loop pipeline (compile→run→profile→fix) on real CPU+GPU toolchains to see what actually breaks. @OpenAIDevs

[Gal Oren @GalOren8]

@OpenAIDevs Paper: https://t.co/1KgO4eAETk
Code: https://t.co/0U1nyEL5C2

[Gal Oren @GalOren8]

@PNASNews PNAS: https://t.co/EUQl0HlUki
Code & data: https://t.co/XuDhFwEL2Y
@OpenAI @OpenAINewsroom @OpenAIDevs @ChatGPTapp

[Gal Oren @GalOren8]

What if a general LLM could become a biological instrument with the right fine-tuning? In @PNASNews, we present ADAR-GPT: a #GPT model trained step-by-step that learns ADAR targeting grammar, generalizes to new Alu sequences, and captures key constraints from the sequence alone.

[Michael Levitt @MLevitt_NP2013]

This is really exciting work that I am proud to be a part of. RNA is a remarkable material as it has structure and also carries information. My first paper published in 1969 modeled RNA structure in transferRNA.

The paper by @GalOren8 is about using AI to better predict messenger RNA editing sites so that the information it contains is more nuanced.

Biology is so full of amazing hacks.

[Gal Oren @GalOren8]

@MLGenX @MLevitt_NP2013 [8/]

📝 Paper: https://t.co/VtuPAKLnn4
🧬 Repo: https://t.co/IBgkpKhO4H
📺 YouTube: https://t.co/l8qsd8fPVi
With Zohar Rosenwasser, Erez Levanon, @MLevitt_NP2013

[Gal Oren @GalOren8]

🚨 New paper alert!
"Leveraging GPT Continual Fine-Tuning for Improved RNA Editing Site Prediction"
📍Now live at @MLGenX @ #ICLR2025
🧬🔥 We combine NLP + genomics to improve A-to-I RNA editing site detection using GPT models.

[Gal Oren @GalOren8]

@MLGenX @MLevitt_NP2013 [7/]

🤖 More:
— No hand-crafted features
— Everything end-to-end from raw RNA + structure
— Ready for broader use in RNA therapeutics, gRNA design, etc.

[Michael Levitt @MLevitt_NP2013]

@GalOren8 has done something remarkable in AI for Science by teaching ChatGPT the language of RNA. I am so proud to be involved in this project with him and Erez Levanon.

[Gal Oren @GalOren8]

@ElbazYonatan הם ודאי מסתדרים בלעדינו ;) בטח לא צריכים את OpenAI

[Gal Oren @GalOren8]

🎉 Excited to share our latest research published at AIDrugX @ NeurIPS 2024! We've developed an innovative approach to detect RNA editing sites using GPT fine-tuning. A thread 🧵👇 #NeurIPS2024 #AI #Genomics #RNAEditing