New preprint "HOMED enables hierarchical and multimodal optimization of DNA methylation deconvolution across tissues": https://t.co/OZvlPSuoh1 HOMED deconvolutes complex tissues such as placenta, with the aid of single-cell data, solving the critical heterogeneity issue in EWAS.
Congratulations to Dr. Tay for successfully defending his PhD on March 27th! ๐Tay has been working on drug repurposing and women's health with dissertation titled: Precision Medicine with Single-Cell and Spatial Transcriptomics: Applications to Preeclampsia
@GarmireGroup
Another new paper from our group: "Investigate the Effects of Preeclampsia Severity, Race and Fetal Sex on Subsequent Maternal Complications Using EHR Data From Over 100,000 Pregnancies" with cross-insitutional validation @CedarsSinai@VUMChealth Link: https://t.co/LZOPViZFuw
Congratulations to Xiaotong for the GigaScience paper "Cord blood DNA methylation and cell type composition are not significantly associated with severe preeclampsia, after cell type and clinical covariate adjustment". Link: https://t.co/Il9WGgk5Uc
Just published!
Our latest review in "Seminars in Nephrology" summarizing recent advancements, key challenges, and potential solutions in #omics data integration in #nephrology, supporting the goals of #PrecisionMedicine.
Co-authored with Yuheng Du, PhD student at the lab of the great Dr. @GarmireGroup at the @UMich and in collaboration with the talented Tianqing Feng, computational scientist at the Center for Precision Medicine @UTHealthSA!
Grateful for the opportunity to learn from Dr. Garmire, awardee of US Presidential Early Career Scientists and Engineers in 2019!
#MultiOmics #Nephrology #PrecisionMedicine #BiomedicalResearch #GarmireLab #CenterForPrecisionMedicine
Center for precision of Medicine: https://t.co/bDBWFOPziu
@GarmireLab : https://t.co/evfmfSSlr1
@UTHealthSA@UTHSAResearch@UTHealthSAlumni@UTHealthSA_UP @UTHealthSA_OPA @IIMSCTSA@utsystem@UTHealthSANeph
Take a look ๐๐
Congratulations to Yuheng and all co-authors! ๐The multi-ethnic and multi-omics study on the effect of maternal obesity including the Native Hawaiian population has been accepted in principle for publication in GigaScience. Link to preprint: https://t.co/T049ya1lqE
Congratulations to Tay and all co-authors! Originator has been officially accepted for publication in Genome Biology. ๐"Originator, a computational tool separating single-cell RNA-seq by genetic and contextual information".
New preprint from Garmire's Lab (under review at Genome Biology): Originator, a novel tool that deciphers single cells by genetic origin and separates immune cells of blood contamination from those of expected tissue-resident cells. Link: https://t.co/tdtOgmVF24
Updated preprint (under review at GigaScience): Leveraging a maternal obesity model for the independent prediction of cancer status in TCGA samples. Explore the intersection of maternal health and cancer biology: https://t.co/T049ya1lqE
New pre-print from our group on a unique Native Hawaiian and Pacific Islander (NHPI) cohort examining the impact of maternal pre-pregnancy obesity with multiome: https://t.co/JV6gyuyA6W #Obesity#MaternalHealth#Epigenetics#Multiomics
New preprint from Garmire's Lab (under review at Genome Biology): Originator, a novel tool that deciphers single cells by genetic origin and separates immune cells of blood contamination from those of expected tissue-resident cells. Link: https://t.co/tdtOgmVF24
New revised preprint from Garmire's Lab: Discover overlooked complications after #preeclampsia from three real-world medical record datasets of over 100,000 pregnancies https://t.co/CnwIit7Tnj Utilizing large-scale #EHR data from @umichmedicine@CedarsSinai and UKBiobank
Belated congratulations to @jenny589446011 who was co-advised by me and Dr. Jian Kang in @umichsph biostat. She graduated with PhD and now is a postdoc with @rafalab. ๐คฉโค๏ธ
Belated congratulations to @jenny589446011 who was co-advised by me and Dr. Jian Kang in @umichsph biostat. She graduated with PhD and now is a postdoc with @rafalab. ๐คฉโค๏ธ
New pre-print from our group on a unique Native Hawaiian and Pacific Islander (NHPI) cohort examining the impact of maternal pre-pregnancy obesity with multiome: https://t.co/JV6gyuyA6W #Obesity#MaternalHealth#Epigenetics#Multiomics
Recent lab outing to celebrate the start of a new school year ๐ญ๐งช๐ฌ๐งฌ Excited to welcome visiting students from HUST and USTC, along with our new Masterโs, PhD students, and RAs this semester! #Bioinformatics#worklifebalance