Exercise isn’t one response. RNA-seq shows it varies by tissue, sex and time of day; metabolomics reveals organ-specific rewiring. Single-nucleus sequencing in muscle shows which cell types drive adaptation, plus epigenetic changes bulk assays miss. https://t.co/1J7Ln1CoTG
Human performance emerges from complex interactions among molecules and cells throughout our body.
We have a limited registration spots for the Wu Tsai Human Performance Alliance symposium at Salk
@WuTsaiAlliance@salkinstitute
https://t.co/DjTCk99veC
The Huberman Lab podcast episode releasing this Monday coming is with @SatchinPanda of @salkinstitute about time restricted feeding, circadian health, and even circadian shifts in human dynamics. Deep on biology and actionable tools.
Stay tuned.
Time restricted feeding in mice improves the diurnal gene expression rhythms. ~60% of the genome becomes rhythmic & peaks in anticipation of food or fast.
Major effects in Lungs, kidney, heart, liver and jejunum. @DeotaShaunak@salkinstitute
https://t.co/LBCsPfqimM
My lab is always open for smart and ambitious students, trainees and researchers from diverse background. Our lab member @DeotaShaunak on why @salkinstitute is an awesome place to pursue your scientific passion.
Please apply through Salk career portal
https://t.co/cPUdZ5b1cZ
Circadian medicine again features for #sciencesunday, with this @guardianscience article featuring @davidra17581122@R_Dallmann and Sridhar Vasudevan @OxSCNi. There's so much scope to improve medicine by taking our body clocks into account:
https://t.co/pioEDy9I9X
I'm very excited to share that our research on TRE to improve the health of firefighters on 24-hr shifts is now published! And we got the cover!! @SatchinPanda@PamTaubMD@AdenaZadourian@SDFD https://t.co/hapwBjjOtN
So many interesting points to take from this article!
Personal highlight: South Asia had the highest food quality score, due to higher whole grain and lower red/processed meat and sugary drink consumption.
https://t.co/9La70F6M85
The relationship between the #circadian system, #sleep and diseases is complex. In this @NatureRevGenet article, the authors review discoveries from genetic studies of circadian and sleep phenotypes and linked this to human health and disease. https://t.co/8SXGRPKeGi
This article in @NatRevMCB extensively reviews #SatelliteCells quiescent and activation in #muscleregeneration, age-dependent satellite cell impairment, and possible therapeutic strategies to improve regeneration.
https://t.co/VtWaEWfjtc
Very happy to announce the launch of my science podcast: #247MUSCLE 💪
My aim:
Translational knowledge from research for students, coaches/athletes & interested public!
Topics:
#muscle#chronobiology ⏲️ 🌡️
#circadian 🌅🌇🌃
#exercise 🚴♂️ 🏃♀️
#sleep 😴
https://t.co/RbpTwwBHvE
Reducing calories by 30% = mice lived 10% longer
CR + eating when mice usually sleep = +10%
CR + eating at at the right time = + 15%
https://t.co/vgyE8R3xPv
We will not see the real data in this #TRE paper. Because #NEJM allowed the authors not share any data. Terrible data sharing policy at #NEJM.
https://t.co/8sAE44vO7P
COVID highlighted the sad truth about how diabetes and metabolic diseases are debilitating and life threatening.
Nurturing our circadian rhythm can prevent or improve these conditions. So, I decided to write my next book.
THE CIRCADIAN DIABETES CODE.
https://t.co/Pj55l51ZH5