Ghosn Laboratory

Ghosn Laboratory | Emory University | Account managed by lab members

[Leonard Calabrese @LCalabreseDO]

The real implications of this impressive work is to why we make these autoAbs? This supports a physiological role @casanova_lab

Transient anti-IFN autoantibodies in the airways are associated with recovery from COVID-19 | Science Translational Medicine https://t.co/QL8qEM9THI

[Jeroen den Dunnen @DrDenDunnen]

In some cases, autoantibodies can actually protect you during infection 🤯. Fascinating meticulous study by @EliverGhosn in @ScienceTM about anti-IFN IgA in #COVID19, which could change our general perspective on autoimmunity: https://t.co/YoXhlmvbOU

[Ghosn Laboratory @GhosnLab]

There's always something worth celebrating in the lab. This week it's our traditional lab competition: the cookoff. Congratulations to this year's "chef laureates" Krishna Kothari and @EliverGhosn! Runner-up recognition to @bazzano_julia, Justin Hahm and Collin Leese-Thompson.

[Emmanuel @ejustin46]

NOSE ANTIBODIES may help REGULATE the IMMUNE RESPONSE and promote RECOVERY against COVID-19

An amazing study 💯👍
Thanks to @DavidJoffe64
https://t.co/c32BwcGgqT

[Benjamin Babcock @ben_r_babcock]

So, so proud to see our work read and discussed.
This came together as a beautiful story describing an unexpectedly beneficial autoreactive antibody response in the nose during COVID-19.

Thanks @GhosnLab and @EliverGhosn. Summary below and more here: https://t.co/OBNpogSYvP

[Emory Technology Transfer @EmoryOTT]

#News New @EmoryUniversity research highlights the therapeutic potential of an enzyme in managing immune-related disorders. Eric Sundberg, professor and chair in the Department of Biochemistry at @EmoryMedicine, was principal investigator on the study. https://t.co/dRMdSopFgJ

[Emory Health @emoryhealthsci]

New research from Emory University is providing a more precise prediction of COVID-19 severity that can be found by looking at autoantibodies in the nasal cavity.

➡️ Details: https://t.co/Gn2y1KY2oH

[Michal Tal, PhD @ImmunoFever]

This is such an important paper from @EliverGhosn @GhosnLab which I really hope is the start of how we collectively begin to appreciate the importance of the relation between isotype/subtypes of antibodies produced, beyond the antigen they target, whether a self epitope or not.

[Ghosn Laboratory @GhosnLab]

@ImmunoFever Thanks so much for the highlight Michal! We're very proud of this story and will be posting our own summary thread soon!

[Eric Topol @EricTopol]

The 2 sides of autoantibodies to interferon-α, like a rheostat
—Pre-existing in the blood: linked to high risk of life-threatening Covid
—Induced by #SASRCoV2 in the nose, airways mucosa: Protective
https://t.co/bugYYjJrez @ScienceTM @EliverGhosn @GhosnLab @ben_r_babcock

[Ghosn Laboratory @GhosnLab]

So proud of our entire team for bringing this story together!

[Ghosn Laboratory @GhosnLab]

A new paradigm for autoantibodies in mild #COVID19?
Our PI @EliverGhosn summarizes the lab's newest manuscript:

[Benjamin Babcock @ben_r_babcock]

The @GhosnLab, @EliverGhosn and our collaborators from Emory/UCSF/Gladstone showed that transient autoantibodies against type-I interferon (IFN) are a common feature of the SARS-CoV-2 response, and are associated with efficient COVID-19 recovery. https://t.co/IWDWRAaoLb 2/

[Ghosn Laboratory @GhosnLab]

Thanks for the summary of our new manuscript by lab member @ben_r_babcock, @EliverGhosn and our collaborators across Emory/UCSF/Gladstone!

[Vipin M. Vashishtha @vipintukur]

The epithelium of the nasal mucosa is the initial site of SARS-COV-2 exposure and infection. As such, antiviral immune responses mounted locally in the nasal mucosa can play a role in determining disease recovery or progression to severe COVID-19. 1/

[Benjamin Babcock @ben_r_babcock]

We often think of autoantibodies (anti-self) as flaws in immunity which lead to more severe viral infections, like COVID-19. @GhosnLab and collaborators show anti-interferon autoantibodies associate with recovery from COVID with less severe symptoms. How could this work? 1/Thread

[Ghosn Laboratory @GhosnLab]

Congratulations Alex from all of the lab members!

[ImmunoHorizons @ImmunoHorizons]

#NewinIH: @EliverGhosn @GhosnLab @EmoryMedicine provide optimal conditions for complete #SARSCoV2 inactivation to permit safe transfer from BSL3 to BSL2 environments | #ReadIH #OpenAccess #immunology 👉 https://t.co/63k0vcMvEU

[Ghosn Laboratory @GhosnLab]

More photos of the dishes to come soon!

[Ghosn Laboratory @GhosnLab]

In the most competitive year yet, congratulations to @EliverGhosn and @AlexNazzari for winning the 2022 Ghosn Lab cookoff event!

[Ghosn Laboratory @GhosnLab]

The winning dishes in each category were kibbeh with fresh hummus (Eliver) and pumpkin pie bars with homemade ice cream (Alex). Both were at the top of a VERY crowded field. Congratulations!