๐ผ๐๐๐-ฮต4 and ฮต2 effect in Alzheimer's Disease varies across populations!
Check our findings in the largest collection of Hispanics/Latinos now published in @alzdemjournals
๐ฐ https://t.co/msVuwEN5r0
Check out our lab's latest software!
๐ฆ๐๐๐ runs ๐ด๐ฒ๐ป๐ผ๐บ๐ฒ๐๐ถ๐ฑ๐ฒ ๐ฎ๐๐๐ผ๐ฐ๐ถ๐ฎ๐๐ถ๐ผ๐ป ๐ฎ๐ป๐ฎ๐น๐๐๐ฒ๐ with a simple one-line command! Anyone can access complex genetic analyses ๐
[developed by the talented Basilio Cieza]
๐https://t.co/xEEQkUI7l1
Presenting my preliminary results of APOE e4 and Ptau 217 over cognition in quechua and aymara population from GAPP study at #AAIC25 in Toronto. Thanks to @GiusToLab, @NiltonCustodio8@marciosotoanari
How does APOE status impact AD risk in Hispanics/Latinos?
Research in A&D report APOE ฮต4 shows a heterogeneous effect on ADRD risk across Hispanic/Latino populations, with the strongest associations in Peruvians/Bolivians #AlzResearch
https://t.co/7QLayScb56
What does heritability mean as measured multiple ways and what does it mean for our understanding of Alzheimer's?
Alzheimer disease is (sometimes) highly heritable: Drivers of variation in heritability estimates for binary traits, a systematic review https://t.co/QegGuZEq7W
Took a minute (4+ years๐ ), but we made it!
We studied the heterogeneity of APOE and Alzheimer's Disease risk using the largest collection of Hispanic/Latino studies - an amazing collective effort๐
https://t.co/msVuwENDgy
I wrote about how population stratification in genetic analyses led to a decade of false findings and almost certainly continues to bias emerging results. But we are starting to have statistical tools to sniff it out. A ๐งต:
Finally out our paper on ptau217 and AD in Peruvian populations!
A huge effort for the GAPP study, an exceptional cohort of participants from Lima, Arequipa and Puno with deep phenotyping, genetics, plasma and serum available for the scientific community!
https://t.co/kG1UYAzDq2
Closing day at the Brain Ageing and Dementia in LMICs 2024 conference in Nairobi, Kenya ๐ฐ๐ช
Dr. @pericakvance taking the stage to present our @NIHAging funded DAWN study for which we have been recruiting thousands of seniors in US and Africa
https://t.co/lLIrEqszeT
We now have a zebrafish model ๐ to better dissect the genetics underpinning Fetal Alcohol Spectrum Disorders #FASD - thanks to @CaKizil@gaattagca@NIAAAnews
preprint here ๐๐ผ
https://t.co/hMYVGnUMCS
A new project from our lab!
Fascinating #admixture study on this underrepresented South African population and the risk profile for Fetal alcohol spectrum disorders #FASD.
1% to 5% of U.S. first graders have FASD! @NIAAAnews
https://t.co/Holahwrjoq