GlioModel

We are a multi-Institute UK consortium that, together, house a full range of preclinical models for GBM target validation

[GlioModel @GlioModel]

This position paper highlights the need for better experimental models, but also *better access* to a *range* of different models, for brain tumour research. The most complex organ in the human body needs a multifaceted experimental approach to understand the diseases within it!

[Lucy Stead @LucyFStead]

Pledges to increase brain tumour research funding in the UK have not improved outcomes, as was hoped. Our position paper opines why "Adult brain tumour research in 2024: Status, challenges and recommendations" https://t.co/7OPNfSHRjk @KarinPurshouse @allyrooney @jenkinsonmd

[GlioModel @GlioModel]

Just published 🥳A @UniOfHull & @GliomaGenomics collaborative study using a 'GlioModel' (brain tumour biopsies kept viable on chip)🧠👀👉https://t.co/58zTskoxrF funded by @YorkshireBTC. Patient-derived models included thanks to @LeedsNeuroRTB. Huge congrats @AntoniaBarry18 👏

[GlioModel @GlioModel]

We love models, but we also love finding out about all the hugely advanced technology we can apply to learn as much as possible from them! Investigation of GBM cell plasticity NEEDS single-cell multi-omics!

[Leeds'Omics @leedsomics]

If you're interested in Spatially Resolved, Single-Cell Transcriptomics & Proteomics, join us @ 2pm, Worsley 9.60 or alternatively via TEAMs for the seminar
“Nanostring: Multi-Omic, Spatial Profiling at Single-Cell Resolution to Unravel Complex Biology”
Speaker: Dr.Bryan Serrels

[Leeds Centre for Disease Models @DIMOLeeds]

We are excited to announce Leeds Centre for Disease Models Annual Meeting on the 8th of March@Nexus to @UniversityLeeds community. 🗣️📯🥳
Please register here: 🧑‍💻https://t.co/HfVQHYxvnx (tickets are limited)

[Mohamad Amki @mohamad_elamki]

Microrobots in the brain Vasculature!  
We use microrobots and control them wirelessly in the brain vessels (even against the flow).
We are just at the beginning of this exciting field.
What kind of application do you imagine?
https://t.co/61Y7AumrXJ #innovation #medtech

[Marie Boyd 🇺🇦 @pinkbools]

Great to meet with colleagues this morning to discuss all things @GlioModel . So important to bring people together from across Institutes and Universities and disciplines. @NatiGomezRoman @StrathScience @Healthcarefut #Braintumour #Glioblastoma

[GlioModel @GlioModel]

Exciting news! Funded brain tumour research and a chance to further show proof of concept to get GlioModel up and running. Well done Dr Jane Alder!

[University of Lancashire @Uni_Lancashire]

Local #Blackburn @braintumourrsch charity #Inbetweenears will fund another @PABSUCLan #PhD student to conduct vital #BrainTumour research as part of the @GlioModel with @LucyFStead
https://t.co/wSHIwiwdRW

[Leeds Centre for Disease Models @DIMOLeeds]

Exciting news alert 🗣️📯: we are delighted to let you know that our 2023 disease models 🧫👁️🧠🫀🫁conference will be taking place on Wednesday the 8th of March at NEXUS. Please save the date and more details to follow soon ✍🏼

[Michael Cearns @MDCearns]

Exciting to hear @LucyFStead discuss the power of collaborating on #glioma models across the UK with @GlioModel. #BTNW #BrainTumour

[GlioModel @GlioModel]

State-of-the-art experimental models need state-of-the-art analysis techniques. Out today in JBM: 'SpheroidAnalyseR—an online platform for analyzing data from 3D spheroids or organoids grown in 96-well plates' @GliomaGenomics @Rhiannon_Barrow @LucyFStead https://t.co/QwxJRs3t6v

[Leeds Centre for Disease Models @DIMOLeeds]

We are looking for an enthusiastic PGR to join the Leeds Centre for Disease Models Executive Committee. If you are actively involved in cellular disease models and would like to help shape this research area and community at the University of Leeds, please get in touch!

[Marie Boyd 🇺🇦 @pinkbools]

Really great to catch up with colleagues today in @GlioModel on zoom. Superb collective who are aiming to establish validated glioblastoma models to aid in all glioblastoma research. So excited for what is ahead! Thanks to @LucyFStead for organising

[Lucy Stead @LucyFStead]

Please note that @LeedsNeuroRTB is a brain tumour tissue bank open to ALL researchers. Just email [email protected] to apply. Huge thanks to @YorkshireBTC and @OscarsCharity for facilitating so much research

[Lucy Stead @LucyFStead]

LOOK 👀 a special research topic in @FrontCellDevBio on GLIOMA: From Genetic to Cellular Heterogeneity 🧠🧬There's so much exciting research in this area right now. Submit your abstract by 24th Sept✏️ & manuscript by 23rd Nov🖊️More info here 👉
https://t.co/TKrrVXwPum Pls RT

[GlioModel @GlioModel]

Hugely informative and entertaining talk on organoid development and assays by latest GlioModel member @jamesapoulter who was also one of the organisers for this @DIMOLeeds Organoid workshop 👌👍👏

[GlioModel @GlioModel]

@Rhiannon_Barrow from @GliomaGenomics presenting on SpheroidAnalyseR, an automated programme for measuring growth of preclinical 3D models, at @DIMOLeeds Organoid Workshop

[GlioModel @GlioModel]

A full house for the @DIMOLeeds Organoid Modelling workshop starting with @linda_lako from @UniofNewcastle on her state of the art retinal organoids. A full day of exciting talks and discussion ahead @UniversityLeeds @LeedsCancerRes @LIMRLeeds

[Yorkshire's Brain Tumour Charity @YorkshireBTC]

Dr @LucyFStead explains how the @GlioModel consortium is allowing collaboration for GBM researchers across the country

[GlioModel @GlioModel]

@Rhiannon_Barrow presenting work that used 3D GBM spheroid models to gain real clinical insight. To facilitate this she developed https://t.co/HYg6zprnqA for automated analysis of spheroid imaging data #BNOS22 @BNOSofficial @DIMOLeeds

[Glioma Genomics Research Group @GliomaGenomics]

Our very own @Rhiannon_Barrow presenting her @BRUKresearch funded work on GABA signaling modulators as potential stratified therapeutics for GBM at #BNOS2022. @BNOSofficial @LIMRLeeds @LeedsCancerRes

[GlioModel @GlioModel]

We used the opportunity, whilst in Liverpool at #BNOS22, to visit GlioModel member Prof Harish Poptani's amazing imaging setup for preclical glioma models. We see so much opportunity for sharing of these kinds of resources in our consortium to expedite target validation in GBM!