Discovery of highly selective ligands for GPCRs based on high-resolution biomolecular structures at Friedrich-Alexander University Erlangen-Nürnberg (FAU)
Development of Photoswitchable Tethered Ligands that Target the mu-Opioid Receptor (P. Gmeiner, B. Koenig et al.) @GmeinerGroup#openaccess https://t.co/4l5d6jdx4N
Congrats to @MatthiasSchied2 receiving the Innovation Award in Medicinal/Pharmaceutical Chemistry 🥂
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and very pleased that i have the opportunity to participate in this year's Frontiers conference in beautiful Vienna 🎡#frontiers2023
Published! So exciting that our new antagonists of the T2R14 #bitter#taste#receptor can now be used to explore the #extraoral#physiological roles of this intriguing member of the #GPCR family
https://t.co/8eVJZxmHfM
Discovery of 2-Aminopyrimidines as Potent Agonists for the Bitter Taste Receptor TAS2R14 https://t.co/QgXuoF8c55 - Great collaboration with @GmeinerGroup! Congratulations @LukasWaterloo , well done @fabrizio_fierro !
Inhibiting a promiscuous GPCR: iterative discovery of bitter taste receptor ligands @fabrizio_fierro preprint, with @PeriLior and @GmeinerGroup
https://t.co/8x8lLCODiz
Excited to share the preprint of our recent work "Discovery of 2-aminopyrimidines as potent agonists for the bitter taste receptor TAS2R14" on @ChemRxiv ! Great work by @LukasWaterloo in collaboration with @masha_niv !
https://t.co/vY8E6FiAVT
A warm welcome to @HannahV150120, who is a research visitor from @GmeinerGroup. She is currently completing her PhD in medicinal chemistry with a particular interest in GPCR heterodimerization. She is working alongside Professor @DavideCalebiro's group. #PhD#medicinalchemistry
Happy to share the news that our review on "Small Molecule Tools to Study Cellular Target Engagement for the Intracellular Allosteric Binding Site of GPCRs" was published in Chemistry - A European Journal.
https://t.co/M9iXC9u6Lo
! Big thank you to everyone involved.
We are very happy to share our work out now in @ScienceMagazine!
https://t.co/X6lK7xePlG
Thanks to everyone in the labs of @BShoichet, Basbaum, Du, @Michel_Bouvier as well as @EnamineLtd !
We are excited to be part of the #4GPCRnet conference and to talk about our latest research with this phenomenal crowd of GPCR enthusiasts from all over the world.
Happy to share the great news that our work on fluorescent ligands targeting the intracellular allosteric binding site of the chemokine receptor CCR2 was published in ACS Chemical Biology (ACS Publications).
https://t.co/HYjR3be5Ah
! Big thank you to everyone involved.