Gothelf lab

Nucleic acid chemistry, organic synthesis, bioconjugation, biomolecular drugs, DNA-nanotechnology, biosensors.

[Gothelf lab @GothelfLab]

The work by Mads K. Skaanning and other members of our team on the self-assembly of (L)-acyclic threoninol nucleic acids into ultrasmall wireframe nanostructures was recently published in JACS. https://t.co/tUaTG2Bpof, @iNANO_AarhusUni, @Chemistry_AU

[Gothelf lab @GothelfLab]

Jakob Smidt from our lab visited Lennart Lykke @novonordisk during his PhD studies and the collaboration resulted in a method to conjugate GLP1 to any phosphate in siRNA. See the resulting paper in Nucleic Acids Research. https://t.co/8Tjruychra. @iNANO_AarhusUni, @Chemistry_AU

[Gothelf lab @GothelfLab]

Reversible protection of DNA origami by a cationic disulfide polymer that is cleaved inside cells is reported in Small by Sarah Youssef @SarahYo45655307 and other members of our team. @iNANO_AarhusUni, @Chemistry, https://t.co/RVJ8D13tEX

[Gothelf lab @GothelfLab]

Triplex DNA blossoms on the front cover of Advanced Materials featuring our Triplex Origami methodology. The cover art is entirely made out of real folded paper! By postdoc @MinkieWinky and PhD student Emily Tsang. Read the article here: https://t.co/msjOSNLVHI

[Gothelf lab @GothelfLab]

@baukevon @iNANO_AarhusUni @Chemistry Thank you! I am also looking forward to the IUPAC/CHAINS 2023 conference.

[Gothelf lab @GothelfLab]

So far, DNA nanotech has almost exclusively relied on Watson-Crick base interactions. In our new paper in Advanced Materials, we show that Hoogsteen interactions have the same potential to organize double-stranded DNA. @iNANO_AarhusUni, @Chemistry, https://t.co/0hKFnrwV7h

[Gothelf lab @GothelfLab]

@DNA_Nanotech @iNANO_AarhusUni @Chemistry Thank you, Yoel!

[Gothelf lab @GothelfLab]

@iNANO_AarhusUni @AarhusUni @novonordiskfond @AarhusUni_int @MolBiolAU @roskildeuni @ETH_en @kjems_rgen @CellPAT_AU We are looking forward to take part in the development of new RNA therapeutics in this center.

[Gothelf lab @GothelfLab]

Congratulations to Minke Nijenhuis for winning the excellent student or post presentation award at FNANO2023, where she presented our work on triplex origami and we also had a reunion with two former GothelfLab members Zhao Zhang and Abhichart Krissanaprasit.

[Gothelf lab @GothelfLab]

"Automated Solid-Phase Oligo(disulfide) Synthesis" is now online in Angewandte Chemie and special thanks to Martin Frandsen and Alexander Sandahl who have led this work. https://t.co/E7s9hnJHot

[Gothelf lab @GothelfLab]

Happy to share our recent preprint on folding double-stranded DNA into designed shapes with triplex-forming oligonucleotides: https://t.co/XAzwTXI9VB

[Gothelf lab @GothelfLab]

Our latest paper on bioconjugation, that was made in collaboration with Novo Nordisk A/S, was selected for editors favourite recet articles over at OBC. https://t.co/aWRgXhhkGI
#Gothelflab #realtimechem #NovoNordisk #ChangingDiabetes

[Gothelf lab @GothelfLab]

Line and Malthe from the Gothelf Lab at #AarhusUni has spent the last 3 months in Copenhagen at the #BioInnovation Institute. If you're curious to hear what they've learned, you can watch at 15.30 using this link:
https://t.co/C1oSd3CZv7

#Science #chemistry #bioscience

[Veikko Linko @VeikkoLinko]

Professor Kurt Gothelf ⁦@GothelfLab⁩: The DNA origami method will undoubtedly influence development of new medicine ⁦@AaltoUniversity⁩ ⁦@nantech2019⁩ https://t.co/4R130ea534

[Gothelf lab @GothelfLab]

A close collaboration between #NovoNordisk and our lab at #iNANO has resulted in a recent publication in #AngewandteChemie.
#Science #Chemistry #biotech

For more information and link to the article, please visit: https://t.co/AaULGwcl6i

[Gothelf lab @GothelfLab]

PAPER: Researchers from the Gothelf lab has recently published a mini review in #ChemBioChem on how to design probes for affinity guided protein conjugation.
#Chemistry
https://t.co/wAM42Q7bGj

[Gothelf lab @GothelfLab]

PhD student Mette Riis Bakke from the @GothelfLab will be having her qualifying exam this Wednesday.
https://t.co/Y4ggaxhks0

[Gothelf lab @GothelfLab]

Our most recent review about "Chemistries for DNA Nanotechnology" https://t.co/KjRK2e0QsW

[Gothelf lab @GothelfLab]

Quantitative Detection of Digoxin in Plasma Using Small‐Molecule Immunoassay in a Recyclable Gravity‐Driven Microfluidic Chip - Li - - Advanced Science - Wiley Online Library https://t.co/TTrshW4XeX

[Gothelf lab @GothelfLab]

Selective delivery of doxorubicin to EGFR+ cancer cells by Cetuximab‐DNA conjugates - Gothelf - - ChemBioChem - Wiley Online Library https://t.co/Rge6Bxzd2Z