Granada Lab

Natural Scientists

[Granada Lab @Granada_Lab]

Major work out in @NaturePhysics!
Led by @NicaGutu & Malthe Nordentoft — a multi-lab collaboration.

We show that the degree of circadian coherence between cells tunes proliferation rate 📈.

Disrupting coupling breaks clock–cell cycle coordination.
👉https://t.co/8rSV1ZVtJ6

[Carolin Ector @CarolinEctor]

It’s a wrap! My final PhD paper in the @Granada_Lab just came out in @CellReports🥳 We identified circadian rhythm heterogeneity and distinct time-of-day drug sensitivity dynamics across neuroblastoma cell models⏰ Thanks to everyone who shaped this work! https://t.co/QmL2dCuQwD

[e:Med Systems Medicine @medicine_e]

Stay up to date with the latest research from e:Med by e:Medium Flash, March edition https://t.co/nBag8ihY7d

[Granada Lab @Granada_Lab]

Huge team effort including @AnnaMarieFinge1, @CarolinEctor & many others — grateful for such a collaborative group. Very thoughtful reviewers’ feedback helped strengthen the work.

Thanks to @medicine_e, @BMBF_Bund & @ChariteBerlin for supporting this project!

[Granada Lab @Granada_Lab]

Major work out in @NaturePhysics!
Led by @NicaGutu & Malthe Nordentoft — a multi-lab collaboration.

We show that the degree of circadian coherence between cells tunes proliferation rate 📈.

Disrupting coupling breaks clock–cell cycle coordination.
👉https://t.co/8rSV1ZVtJ6

[Granada Lab @Granada_Lab]

Our latest work is out in @CommsBio. Led by @NicaGutu & Hitoshi Ishikuma, we study how circadian rhythms shape time-of-day drug sensitivity in human cells 🕒💊. Toward time-based cancer therapy.
Supported by @medicine_e, @BMBF_Bund @ChariteBerlin
👉 https://t.co/OaX1oCEeRH

[Granada Lab @Granada_Lab]

Happy to share a new very exciting work from my lab! Congrats to @CarolinEctor and the team on their study of circadian clock dynamics in breast cancer cells, now published in @MolSystBiol. @medicine_e @ChariteBerlin funded by @BMBF_Bund

[Carolin Ector @CarolinEctor]

Excited to announce that my second study with the @Granada_Lab, where we elucidated diverse circadian clock dynamics across breast cancer cells and their effect on drug sensitivity, has been published in @MolSystBiol. Thank you to the entire team! https://t.co/BM2il6of5K

[Granada Lab @Granada_Lab]

🚀 Together with @CarolinEctor, we recently published a review in Deutsches Ärzteblatt on Chronobiology in Oncology. Timing therapies for optimal effectiveness! ⏰💊
📌 Currently only in German.
🔗 https://t.co/R1XEaDTy0E
#Oncology #Chronobiology #MedicalResearch #CancerTreatment

[Granada Lab @Granada_Lab]

Exciting to see this out! Congrats to @Anton36193637 and @shaon_chak ! — fantastic work all around!

[Shaon Chakrabarti @shaon_chak]

Big shoutout to @Anton36193637, who drove this project over the last 4 years, working hard to make sense of all the noisy datasets using carefully designed models and statistical inference techniques. Thanks also to @Granada_Lab for the discussions and collaboration! (6/6)

[Granada Lab @Granada_Lab]

Thanks to @medicine_e, @BMBF_Bund, @ChariteBerlin
& @DKTK_ for the support! #CancerResearch #Chronotherapy

[Granada Lab @Granada_Lab]

New Preprint from our lab, led by @CarolinEctor! We performed deep circadian phenotyping in breast cancer cell lines, uncovering circadian-based subtypes and showing the clock’s role in drug response, predicting drug sensitivity. #circadianbiology #breastcancer @BMBF_Bund

[bioRxiv Cancer Bio @biorxiv_cancer]

Circadian clock features define novel breast cancer subtypes and shape drug sensitivity https://t.co/cH3ExPRNJU #biorxiv_cancer

[Granada Lab @Granada_Lab]

Grateful for the excitement around our work on the best time-of-day for drug treatments! Thanks to everyone highlighting the emerging science of chronotherapy—a field built on the pioneering work of many we admire.
News summary in 7 languages: https://t.co/c6Nyy2Uizm.
@SRBRHQ

[Carolin Ector @CarolinEctor]

Very nice article from @Inside_PM, highlighting our recent work published in @NatureComms: https://t.co/AFUjwwEZPE

[Charité - Universitätsmedizin Berlin @ChariteBerlin]

Chemotherapie morgens, mittags oder besser abends? Forschende der #CharitéBerlin haben eine Methode entwickelt, mit der der optimale Zeitpunkt für eine Krebsbehandlung bestimmt werden kann. Ihren Ansatz beschreiben sie im Fachmagazin @NatureComms. https://t.co/5kNgZMeTV6

[Charité - Universitätsmedizin Berlin @ChariteBerlin]

Chemotherapy in the morning, at midday, or evening? Researchers at #CharitéBerlin have developed a method to determine the optimum time of cancer treatment. They describe their approach in the journal @NatureComms. https://t.co/bVoVptq1H0

[Granada Lab @Granada_Lab]

New publication from our group! 🎉 Congrats to all authors, led by @CarolinEctor . We developed a method to use tumor cells' internal clocks to optimize cancer therapy. Thanks to @medicine_e , @BMBF_Bund , @ChariteBerlin & @DKTK_ for the support! #CancerResearch #Chronotherapy

[Carolin Ector @CarolinEctor]

Excited to share the publication of my first paper in
@NatureComms, introducing a comprehensive approach to study time-of-day effects of anti-#cancer drugs ⏰

Many thanks to the whole team, especially Adrián @Granada_Lab! Check out our work here: https://t.co/Ro4SmWZqYR

[e:Med Systems Medicine @medicine_e]

News from the e:Med Research Community - e:Medium Newsletter Volume 7 is available here: https://t.co/CB2Pz6iu43 #systemsmedicine #newsletter @KonradAden @Granada_Lab

[InSiDESignalingDynamics @InSiDE_Seminar]

THANK YOU!!!! to the AMAZING cell signaling community for a fantastic inaugural Dynamics and Encoding in Cell Signaling FASEB meeting. We look forward to getting together in 2026!

[Granada Lab @Granada_Lab]

Excited to present at #SRBR2024 @SRBR_Outreach! Join us Wednesday morning for Symposium 17 on Circadian Medicine. Grateful for the support from @medicine_e, @BMBF_Bund, and @ChariteBerlin. #CharitéBerlin

[Granada Lab @Granada_Lab]

Finally out! "Circadian Coupling Orchestrates Cell Growth"! Our study shows how circadian synchronization impacts the coordination of cellular division, shaping collective growth dynamics. Kudos to @NicaGutu! https://t.co/mrrVPFitP1

[Granada Lab @Granada_Lab]

Thanks to the support of @ChariteBerlin
@medicine_e
@BMBF_Bund
and @BSIO_Berlin

[Granada Lab @Granada_Lab]

Check out our latest pre-print! Kudos to Carolin Ector and a stellar team of collaborators for their immense effort. We've pioneered a novel high-throughput method to assess how circadian rhythms influence cellular response to drug perturbation. https://t.co/fHh1otCFKE