.@davidgoggins on how to create your own motivation:
"Everybody has the ability to do it, but they just don't want to."
"They want to keep asking questions and going to seminars."
"Hard work looks horrible, it's not motivating. It looks like a man being stuck in a dungeon and there's no way out."
@hubermanlab
Where BPC-157 peptide comes from and how it affects the body:
- Croatian research group in the '90s isolated BPC-157 from a much larger 40,000-unit peptide naturally found in the gut - it is 15 amino acids long and is not something the body produces on its own.
- Researchers theorized the stomach contained a cytoprotective compound after Pavlov's gastric juice experiments showed healing effects on GI tissue.
- BPC-157 accelerates repair by upregulating VEGF signaling (new blood vessel formation), boosting nitric oxide synthesis, and increasing growth hormone receptors on tendons.
- Corticosteroids normally halt wound healing - BPC-157 administered alongside them maintained or even improved healing outcomes in animal models.
- In mouse models, BPC-157 reduced intoxication, blunted alcohol withdrawal symptoms, and appears to modulate dopaminergic signaling - effects that get far less attention than its musculoskeletal uses.
@AbudBakri on @hubermanlab
Do we have free will?
"There's no space in there to fit in a freewill concept that winds up being in your brain, but not of your brain."
"Basically the challenge is, show me a neuron that just caused that behavior, or show me a network of neurons that just caused that behavior, and show me that nothing about what they just did was influenced by anything from the sensory environment one second ago to the evolution of your species."
"Enormous change can happen, but the last thing that could come out of a view of we are nothing more or less than the sum of our biology and its interaction with environment is to throw up your hands and say, and thus it's no use trying to change anything."
Dr. Robert Sapolsky on @hubermanlab
Creatine dose, benefits & safety from Dr. Rhonda Patrick:
- Standard muscle dose is 5 g/day of creatine monohydrate - the most well-researched form - but muscles are "very greedy" and consume most of it before it reaches the brain.
- Getting creatine into the brain requires higher doses: one German study found that at 10 g/day, MRI scans showed creatine levels rising in key brain regions above what the brain produces on its own.
- Creatine shines under brain stress - sleep deprivation, intense cognitive work, travel fatigue. One study gave sleep-deprived subjects 0.35 g per kg bodyweight (roughly 20-25 g) and they performed not just at baseline but above it.
- The phosphocreatine system has a frontal bias - the brain areas most associated with strategic planning and working memory rely on it most heavily.
"It's one of the most well-studied supplements out there. If it was unsafe, we really would know."
@foundmyfitness on @hubermanlab
How aggressive dieting can lead to rapid weight loss:
More body fat means you can diet more aggressively: "The more adipose tissue (body fat) you have, the more aggressively you can diet without negative consequences."
Rapid dieting is a tool, not a lifestyle: "I'm doing this to give myself a boost at the beginning. At some point I have to transition to something that's a little bit more sustainable."
@BioLayne on @hubermanlab
3 step framework for becoming a healthy, happy & fulfilled man from @profgalloway:
"I loosely break it down into three very reductive qualities."
"The first is to be a provider. Every young man should have a plan and an assumption that at some point he will have to be the economic leader for his family."
"The second is protector. You develop skills and strengths such that you can protect others."
"The third is procreator. We need to stop demonizing young men's desire for relationships and sexual desires - if channeled correctly it makes you want to be a better man."
@hubermanlab
Why we seek unhealthy romantic partners and how to break toxic relationship cycles:
"There are parts of you who took on the worthlessness from being rejected by your parent and are desperate for Redemption."
"What I try to do is to help them see that that redeemer is inside of them."
Dr. Richard Schwartz on @hubermanlab
.@jockowillink on how to detach:
"The solution to your problem is not going to be found in the problem."
"Take a step back, take a breath, broaden your field of view. Detach from those emotions that you're having and make some space."
"Detachment is a superpower."
@hubermanlab
How to reduce nighttime urination:
- Hydrate consistently during the day. Aim for roughly 8 oz (240 ml) per hour for the first 10 hours after waking so you're not playing catch-up at night.
- Cut fluid intake after the 2-3 hours before sleep. Limit yourself to 5–8 oz total between that point and bedtime, as long as you've hydrated well during the day.
- Sip, don't gulp in the evening. Gulping moves fluid through your system faster and increases how quickly it reaches your bladder.are t
@hubermanlab
How to raise your baseline dopamine levels for motivation & drive:
- Get quality sleep: It literally restores dopamine reserves and makes goal-pursuit possible.
- Morning sunlight viewing: It triggers a dopamine-related cascade in the brain. 5–10 minutes on a clear day, 10–20 on a cloudy day, no sunglasses.
- Regular exercise: a mix of cardiovascular and resistance training at least 5 days a week — maintains elevated baseline dopamine independent of the post-workout high.
- Proper nutrition: Tyrosine, the amino acid required to synthesize dopamine, is found in Parmesan cheese, meats, nuts, and certain vegetables.
- Practice non-sleep deep rest (NSDR): It can increase dopamine reserves by up to 65%. A 10–20 minute session of yoga nidra-style body scan breathing is enough.
@hubermanlab
How to build a sustainable healthy diet:
Protein first: aim for 1/3 of every plate to come from a lean protein source - chicken, fish, beef, or whatever you prefer.
Fill the remaining 2/3 with carbohydrates in a 2:1 ratio - fibrous (vegetables) to starchy (rice, potatoes, pasta).
Fat awareness, not fat avoidance: fats are more calorically dense than carbs or protein, so healthy foods like olive oil and avocado can silently spike total calories.
Calorie logging isn't forever - it's an education phase that builds the instinct to make smart swaps on the fly, anywhere.
Sustainability is the filter: "If it was taking away pasta and oatmeal... there's no way I could sustain that."
@trainer2thepros on @hubermanlab
How GLP-1 peptides suppress appetite:
"A peptide, not actual physical food, but a peptide that stimulates neurons that cause changes in the mechanoreceptors of the gut and make people feel full."
"You have a peptide that's released in the gut and that release within the gut causes gut distension which makes you feel full, and by way of neural stimulation of the hypothalamus also activates neural pathways within the brain that trigger satiety."
@hubermanlab
How to avoid shoulder pain in the gym:
- Attach a resistance band to a fixed point, elbow pinned to the torso, and externally rotate to neutral or slightly past the torso. Hold at the end range to confirm the muscle got it there.
- Keep the elbow locked to the side. Lifting the elbow to complete the range means the delt is compensating. A folded towel tucked under the arm makes cheating immediately obvious.
- Use it as a pre-workout neuroactivator on pressing days to prime the rotator cuff before loading, or as standalone shoulder maintenance work on other days.
@trainer2thepros on @hubermanlab
How to find your purpose:
Every person is born a phenomenon: your DNA and early experience have never existed before and never will again. That uniqueness is your source of power.
The process works like archaeology: dig back through childhood memories to find the moments of deep pull. What created an activation state in you, not just passive delight?
Children naturally carry what psychologist Maslow called "impulse voices." These are internal signals pointing toward what you love and what you hate. These are the seeds of your life's task.
The problem: by your teens, those voices get buried under teachers, parents, peers, and social pressure. You enter the work world without the inner radar that should be guiding you.
Finding your purpose isn't about locking in a job title. It gives you a direction, something to navigate by when everything else feels like noise.
@RobertGreene on @hubermanlab
.@davidgoggins explains how to build extreme willpower:
"You find it in the suck, and you find it repeatedly in the suck, to the point where you know exactly who you are."
"Most people are missing something because they don't know who they are, they never examine themselves, they've never done this experiment on themselves."
"There are no f*cking hacks. It's you against you."
@hubermanlab
How & why to build a stronger neck:
- Wrap a 5 lb plate in a towel, lie on a bench, and work all four directions: flexion, extension, and lateral on both sides. Slow and controlled, no explosiveness.
- Start with one round and wait a day, "I guarantee you're going to be sore."
- Neck training won't bulk up the neck the way trap work does. The deep neck muscles simply don't grow to large proportions.
- Back pain during crunches is often a neck strength problem, not a core problem. Women are especially undertrained here.
- A strong neck is also protective: "You become not only just resilient, but potentially life-saving by having a stronger neck."
@trainer2thepros on @hubermanlab
How to overcome procrastination & increase motivation:
"If you were to take that state of being unmotivated or procrastinating and actually do something that's harder than being in that amotivated state, in other words, doing something that's more effortful, even painful, you can rebound yourself out of that dopamine trough much more quickly."
"The key is to figure out something that, for lack of a better way to put it really sucks, really sucks, and yet is safe. And by doing that, you steepen the trough, which we know brings you back to your baseline level of dopamine more quickly."
"If you're cringing as I say this, well then there you go. You now have a tool that you know you cringe even when you just think about, and therefore represents a great tool for you."
@hubermanlab
Easy at home exercise to relieve lower back pain:
"You can literally do it on your bed in the morning: lay enough of your torso on top of the bed so you're not falling off, have your legs hanging off, and do a reverse hyper."
"A lot of times it's weakness in the glutes that's transferring the load to the low back that can't handle it."
"People get the symptoms in the back, but it's the weakness somewhere else that's causing that."
@trainer2thepros on @hubermanlab