Tom Hadfield

PhD Student in Statistics. Keen on Golf and Badminton.

[Oxford Protein Informatics Group (OPIG) @OPIGlets]

New work out in @ChemicalScience our method DEVELOP allows deep generative design with 3D pharmacophoric constraints. Work let by former DPhil @fergus_imrie. https://t.co/DS3cHxYOiX

[Oxford Protein Informatics Group (OPIG) @OPIGlets]

We propose a new method for fragment elaboration that is structure-aware led by D.Phil @Hadfield5595. Incorporating Target-Specific Pharmacophoric Information Into Deep Generative Models For Fragment Elaboration. https://t.co/WcGUv2x1KP

[Digital Discovery @digital_rsc]

Congratulations to Tom @Hadfield5595 & Markus @MDablander, both from @UniofOxford, for winning the poster prizes at #AIChem21, suported by @digital_rsc & @RSC_MolEng 👏🥳🏆

[Tom Hadfield @Hadfield5595]

@OPIGlets The RSE we need, but not the one we deserve 😇

[Oxford Protein Informatics Group (OPIG) @OPIGlets]

New paper from us! The 3D structure of a protein plays an essential role in determining which ligands will bind to it, but many existing generative models do not account for protein structure when generating molecules. https://t.co/EUyCvWT4hN @Hadfield5595 @fergus_imrie

[Tom Hadfield @Hadfield5595]

We've developed a tool for fragment elaboration which explicitly incorporates structural information. My poster for the 3rd RSC-BMCS / RSC-CICAG Artificial Intelligence in Chemistry symposium. #AIChem20posters @OPIGlets