Dopamine, the brain’s so-called “feel-good” chemical, appears to play a significant role in Alzheimer’s disease, OMRF scientist Dr. Mike Beckstead found in a groundbreaking new study. 🧠
Read more: https://t.co/8Wmj6hLiN9
Great week at #SfN24. I learned a ton but the highlight for me was watching @HarrisEdwardB represent our lab by presenting his Alzheimer's (and dissertation) work -- great job! @AM_OMRF
If you’re interested in slice electrophysiology, synaptic dysfunction, or Alzheimer’s disease, come see my talk at #SfN24 in S404 at 2pm on Saturday! @SfNtweets
I dedicate this video to the fly that gave her life for science, but will live forever in silico. She has supercharged the discoveries of the #FlyWire Consortium, and propels us into the digital transformation of neuroscience. Protip: watch with audio on. https://t.co/D9gMnrd7CM
How can we train biophysical neuron models on data or tasks? We built Jaxley, a differentiable, GPU-based biophysics simulator, which makes this possible even when models have thousands of parameters! Led by @deismic_, collab with @CellTypist @ppjgoncalves https://t.co/iMVKnw9YHz
“While applied research appears to be in the ascendancy at the moment, it is important to remember that without an equal and ongoing commitment to basic science, there would soon be nothing to translate into applications.”
https://t.co/qJVoCP982o
Congrats to Kylene Harold of the Humphries lab for winning a “William C. Stanley” Early Investigator award at the Society of Heart and Vascular Metabolism meeting in St. Louis! @harold_kylene@Ken_Humphries@Soc_HrtVasMetab
Hot-rodded vintage electron microscopes, around-the-clock shifts at the lab, huddles by a digital fireplace — and petabytes of brain connectivity data to show for it all.
Glimpse our #electronmicroscopy team's tremendous work as part of the collaborative MICrONS program.
Recent paper from the Beckstead lab: Impact of Unitary Synaptic Inhibition on Spike Timing in Ventral Tegmental Area Dopamine Neurons @mjbeckstead https://t.co/bz9h6xNAkv
@MorningEdition highlighted this incredible study: Ants will amputate the legs of colony mates when injured, and thus increasing chance of survival.
https://t.co/k1IJBH2PFu
Very best thing I did this week was to listen to a lecture on the history of the AP and bioelectricity by @UW_PBIO Prof. Bertil Hille. He is always clear and inspiring!!! His name should appear in red in the title: if you listen, you will know what I mean.
https://t.co/JrE0hAfVRs
👉This is the first study to record the synaptic currents generated by single identified direct or indirect pathway striatal neurons on single pallidal neurons.
🖱️https://t.co/3Ph3FY1hSS
@jaumsjauns #Striatum#ExternalGlobusPallidus#BasalGanglia
I'm thrilled to share our last work directed by @HlneMarie10 published in #neuron. We discovered a new and exciting modulator of #NMDA receptor activity. This is so exciting ☺️! @CNRS@IPMC_sophia@Univ_CotedAzur
https://t.co/cCtv6kJAok