Hasan Zaki Lab

Zaki lab studies molecular mechanisms of inflammatory disorders.

[Journal of Clinical Investigation @jclinicalinvest]

NLRP12 downregulates the Wnt/β-catenin pathway via interaction with STK38 to suppress colorectal cancer: https://t.co/PWF6Xj8L2t
@HasanZakiLab @UTSWNews
#Gastroenterology

[Intestinal Cell News @Intestinal_Cell]

💡 NLRP12 was shown to suppress colorectal #tumorigenesis, but the precise mechanism was unknown.

✔️ Researchers confirmed that NLRP12 regulates tumorigenesis in an #intestinal epithelial cell-specific manner.

@jclinicalinvest | https://t.co/UMa6W6cAtN

[UTSW Department of Pathology @UTSW_Pathology]

Congrats to @HasanZakiLab and colleagues on their new publication in @jclinicalinvest reporting a novel signaling axis involving NLRP12 in colorectal cancer progression! Way to go! @UTSWNews @UTSWScience

https://t.co/EOCG7pjG2k

[Hasan Zaki Lab @HasanZakiLab]

@LukensJohnR It was nice meeting you, John. Enjoyed you talk. Thanks for visiting us.

[John Lukens @LukensJohnR]

Great to see my dear friend Zaki Hasan @HasanZakiLab at UT Southwestern. It was reinvigorating to see so much exciting research and hear about their incredible investments in neuroimmunology.

[Hasan Zaki Lab @HasanZakiLab]

@LukensJohnR @PrajwalGurung Congratulations, Prajjal!

[Hasan Zaki Lab @HasanZakiLab]

@sa_redmond Tenure track faculty positions are open in the Dept. of Pathology at UT Southwestern Medical Center.

[Hasan Zaki Lab @HasanZakiLab]

Happy to see eLife has published an Insight article highlighting our recent study on the mechanism of inflammation during SARS-CoV-2 infection.

Viruses: What triggers inflammation in COVID-19? https://t.co/vAp8VOCd16

[Hasan Zaki @hasanzaki02]

Our paper showing the mechanism of cytokine storm during SARS-CoV-2 infection is now online in eLife. We demonstrate that spike protein, upon sensing by TLR2, induces inflammatory cytokines in macrophages, monocytes and epithelial cells.
https://t.co/9ShbK9SD4W

[Hasan Zaki Lab @HasanZakiLab]

SARS-CoV-2 spike protein induces inflammation via TLR2-dependent activation of the NF-κB pathway https://t.co/QGbMcfhMLi

[Jeff SoRelle @Jeff_SoRelle]

Our 8-plex PCR Genotyping test of @UTSWNews and @texashealth Resources COVID-19+ specimens from the last week shows #Omicron is now the dominant strain at 53%. @UTSW_Pathology @JasonPathology