Heba Afifi

lecturer of Pathology, Alexandria faculty of medicine.

[Charlie Herndon @DrCycloPath]

Post-mortem lung of a COPD patient on long-term steroids with granulomatous PCP, by Dr. Carol Farver at #uscap
🔬H&E: frothy exudate https://t.co/nAtKZ8pxc8
🔬GMS: crushed ping pong balls or cup-shaped cysts with a central black dot https://t.co/3aMc71lu8N
#CrittersOnTwitter #PathBugs #PathTwitter #PathResidents #PulmPath
✅Pneumocystis

[Head Neck Pathol @HeadNeckPathol]

Novel Glomeruloid Adenocarcinoma Arising in the Mandible Harboring EWSR1::YY1
Daniel L. Miller, Justin A. Bishop & Louis P. Dehner
https://t.co/NfgoUWBRJf
#HeadNeckPathol #HNPJ #HeadandNeckPath #Pathology #ENTPath #PathologyTweet

[Janira Navarro @Janiranavarro]

#everydayBST
Spindle cell/pleomorphic lipoma
-Specific features shown in Pic 4
-If you see something that looks like spindle cell/pleomorphic lipoma BUT in different location/ not well circunscribed call it atypical spindle cell lipomatous tumor

Dr Goldblum CCMPS #BSTPath #pathtwitter #PathX #pathology #PathResident #NIPPathX

[Elizabeth Montgomery, MD @LizMontgomeryMD]

Atypical spindle cell/pleomorphic lipomatous tumor occasionally persists locally following incomplete excision, but malignant behavior has not been reported. MDM2 is not altered and RB protein is lost. Like spindle cell and pleomorphic lipoma, it expresses CD34.

[Pathology mcqs @Pathology_mcqs]

Differentiation table summarizing the differences between - lipoma , atypical spindle cell lipomatous tumor and well differentiated liposarcoma.

[Charlie Herndon @DrCycloPath]

#TooCloseToDiagnose? 🧐
A. Tufted hemangioma
B. Infantile hemangioma
C. Pyogenic granuloma
#Pathology #Dermatology #Dermatopathology #DermPath

[Charlie Herndon @DrCycloPath]

Tufted hemangioma: Cannon ball tufts with lymphatic clefts.
https://t.co/AsBrPonVWp
Infantile hemangioma: Distinct lobules of plump endothelial cells.
https://t.co/kaGZNUBtcs
Pyogenic granuloma: Lobular capillaries + collarette.
https://t.co/d2ASOWiMDf

[Sanjeev Sethi @SethiRenalPath]

FAT1 is the target antigen in membranous nephropathy associated with-
1. Stem cell transplant (HSCT)
2. Antibody mediated rejection (ABMR) in allograft.

In this paper we show a temporal ⬆️of FAT1 in MN with ABMR using protocol & for cause biopsies.
https://t.co/kEPANveTiB
1/2

[Silvija Gottesman MD @SGottesmanMD]

Lymphovascular invasion (LVI) in Merkel cell carcinoma. Size of primary tumor does not matter. Even small primary cutaneous Merkel cell carcinomas can have LVI.
#RealLifeDermpath #pathology #dermpath

[@isaalvaradoc @vintage81106614]

The art of grossing. A 68 years old woman with abdominal pain. Final Dx. 3x2cm Gastric Inflammatory Fibroid Polyp. #pathologists #pathresidents #pathTweeter #GIpath

[Felipe D'Almeida @FelipePatologia]

This is a YAP1::TFE3-fused epithelioid hemangioendotelioma

They are more vasoformative than conventional EHE, which harbors CAMTA1 fusions

The tumor cells are arranged in solid nests or vascular structures separated by fibrous septa and display eosinophilic cytoplasm

More pics

[The American Journal of Pathology @AJPathology]

#ArticleinPress: Alcohol‐Associated Hepatocarcinogenesis: Wnt/β-Catenin in Action. From @ASIPath member author Dr. Liya Pi and colleagues from @Tulane.

#OpenAccess text: https://t.co/ycATOLDq5S

[Jay "Thymocyte" Hwang @Path4People]

Not all tumors that produce Calcitonin is Medullary Thyroid Carcinoma

Laryngeal Neuroendocrine Tumors ALSO produce/stain with Calcitonin.

If unsure, get serum 🩸 🧪 Calcitonin; more likely ⬆️ in Medullary

#pathx #pathology #headandneck #ops #entpath #pathtwitter

[Elizabeth Montgomery, MD @LizMontgomeryMD]

Good gosh - I initially mistook this for a rare gastric carcinoma with peculiar oxyntic/parietal cell differentiation. Gulp. Thankfully I realized my error in a reasonable time frame.

[Elizabeth Montgomery, MD @LizMontgomeryMD]

Cytomegalovirus (CMV) gastritis and colitis. Arrows show the stromal colonic viral cytopathic effect. Two arrows show an infected gastric endothelial cell and one shows an infected epithelial cell. The top arrow in the gastric biopsy shows apoptosis, often associated with CMV.

[Henry YANG @HENRYY_MD]

“Nora lesion”- BPOP ( bizarre paraosteal osteochondromatous proliferation). What a bizarre name, like Nora better😝
#pathology #Pathx #PathTwitter #BSTpath
@kis_lorand you agree with me?😂

[Celina Stayerman MD @ariella8]

#GIPath

[JClinPath_BMJ @JClinPath_BMJ]

Its our Gene of the month time again ! 🥁 please for....GATA3!
⛳ Transcription factor in development of T Cells, Breast and Urothelium
⛳ Useful in evaluating metastatic carcinomas
⛳ Possible uses as a prognostic marker
🚨 Beware of pitfalls!! Watch the video to find out more and read all about it here https://t.co/NunxKQpNUh

[Kyle Perry @KyleDPerryMD]

Dealing with an unusual fibromyxoid spindle cell neoplasm (that is MUC4 negative)? Consider PLAG1! #BSTPath, #UmichPath, #BSTpathGoBlue

[Cancer Cytopathology @CancerCytopath]

✨ New this week! Clinicopathological and molecular characterization of non–small cell lung cancer with pericardial effusions

https://t.co/6Eknb9yI17

#CytoPath @markma666666 @darcykerrMD @LJTafeMD @nathrodriguesMD