Jay Hwang

Pathologist 🔬. Co-creator of YouTube’s Pathagonia with @biehlcole. Views = My Own, not my Organization’s. Check us out😃!

[Jay Hwang @Path4People]

Below is a different pap case showing the feared "Litigation" cell. B/c it's single, relatively hidden, it can easily be missed if in a rush.

Compared to above pap, the below cell is much larger, has a higher N:C ratio, hyperchromatic, and with greater nuclear irregularities.

[Jay Hwang @Path4People]

PAP ⬇️

Thoughts? 🤔

#pathx #cytopath #cytology #papsmear

[Jay Hwang @Path4People]

Here is the corresponding Colposcopy showing reactive changes and no dysplasia, as supported by the p16 ihc showing negative to weak patchy staining.

[International Society of Urological Pathology @IntSocUropath]

🚨 ISUP Presents.....

🔬 Dr. Sounak Gupta on “Algorithmic Framework for Kidney Tumor Diagnosis with Illustrative Case Studies”

📅 10 Nov 2026 at 1pm EST via Zoom

Register here: https://t.co/cP51WdBTVY

[Rui Caetano Oliveira @Caetano_Pathol]

Kidney can also have lots of different tumors. Female, 45yo with a metanephric adenoma!. Stains are PAX8 and WT1

[Jay Hwang @Path4People]

Oncotype Dx 🧪

🧬 A 21 gene RT-PCR assay
🦀 Indicated for early Hormone receptor + (ie ER/PR) and HER2 - breast cancer
🫘 Includes pts from 0 to 3 positive LN
🎯 🎯 🎯Shows if patients require or can skip adjuvant chemotherapy, which can lead to side effects 🤧

#pathx

[Kathryn Lindsey @PathologyKate]

This came to me as negative for malignant cells from the cytotech. These deceptively bland cells are all basically all malignant and BER-EP4 positive. Take a guess about their origin. #boardfodder

[Jay Hwang @Path4People]

@pembeoltulu @JClinPath_BMJ @Vik_deshpandeMD @archibhat3 Congratulations 🙌🏼

[Jay Hwang @Path4People]

🛑 🆘 Septic arthritis is a ddx to NOT miss

💧 Fluid appearance: Can be purulent, thick
🦠 WBC Count: Often > 100,000 uL with >75-90% neutrophils
🥼 Gram stain and fluid cultures can confirm
🗺️ Via hematogenous or direct inoculation
💊 Joint drainage, IV antibiotics

[Jay Hwang @Path4People]

60 y/o with PMHx of obesity

10/10 pain in MTP joint of big toe

Synovial fluid below with 30,000/uL WBCs👇

Dx? 🤔 #arthritis #gout #pseudogout #usmle #chemistry #pathagonia #synovial

[Jay Hwang @Path4People]

🛑 Pseudogout is due to abnormal accumulation of calcium pyrophosphate crystals 💎

Often seen in knee joint 🦵

Crystals appear rhomboidal and positively birefringent and can be seen intra and extra cellularly

[Pembe Oltulu, MD @pembeoltulu]

Fifth edition WHO classification: mature B-cell neoplasms;

You can read it, It is totally free;

https://t.co/5ra2BtqkeE

@JClinPath_BMJ @Vik_deshpandeMD @archibhat3 @DrGeeONE

[Jay Hwang @Path4People]

@AMontasserMD @SarasSreeram Thanks for sharing! Did they have a prior heme history?

[Ahmed Montasser @AMontasserMD]

65Y 👴🏼 ⬆️ PSA

Prostate systematic biopsies

Keep your 👀 open!

Not every inflammatory infiltration is non-specific!

#GUpath greets #Hemepath #Pathology #PathX #PathTwitter

[Meredith Herman, DO @MeredithKHerman]

FREE virtual lecture series on core pathology topics, brought to you by @UMichPath
Save this website and share #PathX
https://t.co/5XraUmwp45
https://t.co/ZBu7JM48BV

@Path_SIG @DOResMatch @MatchToPath

[A. Sarah Erem @CakePath]

Rooky Tuesday!
🔬 Warty dyskeratoma 😎🫡💪
🥣 Cup-shaped, keratin-filled follicular invagination
✂️ Suprabasal acantholysis with villi
🎯 Dyskeratosis: corps ronds & grains
🔍 Differentials
• Acantholytic dyskeratotic acanthoma: lacks follicular cup
• Darier/Grover disease: clinical distribution
• Acantholytic SCC: atypia & invasion #pathology #pathologists #pathTwitter #dermpath #dermatology #dermtwitter

[aquifer @jppathpd]

Dx? femur HE #Pathkeys 2024-1p-25 (etc)