#International scientists of #NewYork - wanna tell your story to the world? INet NYC #Instagram is accepting your stories! Submit to
https://t.co/fSdsjtxmRa
Check out our #spotlight on the recent work by Zhang and Zou et al. on how the deubiquitinating enzyme (DUB) Usp14, regulates, and is regulated by, the proteasome. @TrendsBiochem
https://t.co/26aQu6lCVM
Hanna &co @HelenaMSchnell@BrighamWomens@harvardmed discuss recent developments and structural insights regarding chaperone-mediated assembly of the proteasome core particle: https://t.co/K7broYLfcI
Check out our new review on proteasome assembly:
Chaperone-mediated assembly of the proteasome core particle – recent developments and structural insights https://t.co/c0aqVEnJ3u
How to build a proteasome... NVs by Edward Morris & Paula da Fonseca highlighting a recent study by John Hanna & co reporting two CP assembly intermediates
https://t.co/1vQOvbRno5
One of the latest releases at @EMDB_EMPIAR & @PDBeurope: snapshots of proteasome core particle assembly by John Hanna’s lab @harvardmed@BrighamWomens. Our rendering project - https://t.co/a5V0Ihd8dn
In @NatureSMB: Using a technique called cryo-electron microscopy, researchers from @BrighamWomens and @HarvardMed visualized two unique proteasome intermediate structures. https://t.co/rXOtvL0HQK
Helena Schnell et al report #cryoEM snapshots of proteasome core particle assembly, resolve mostly helical Ump1, infer sequence of core particle maturation events. From John Hanna’s lab @harvardmed@BrighamWomens. SBGrid’s Shaun Rawson contributed. https://t.co/koaF7luIzh
Interested in studying structural and functional aspects of proteasome biogenesis?
Our lab is recruiting:
https://t.co/2oYA19fkRc
Shown below is a cryo-EM structure of the 13S proteasome core particle assembly intermediate (3.6 A).
Amongst todays releases at @EMDB_EMPIAR & @PDBeurope is this entry of a Pre3-1 20S proteasome core particle resolved to 2.74 Å by #singleparticle#cryoem.
Map: https://t.co/8pYqb981Hy
Model: https://t.co/j4oJaN8mMd
Paper: https://t.co/KzZ1XQqcI0
EMDB: https://t.co/d9w7tTiL3G
Assembling a destruction machine: #cryoEM structures of assembly intermediates of the proteasome 20S core particle reveal early steps in proteasome biogenesis
https://t.co/oVRCG3XOV2
Excited to share our recent structural discovery showing the interplay of chaperones with 20S proteasome precursors shedding light on proteasome assembly.
Spoiler: We describe the structure of Ump1!
@NatureSMB https://t.co/TJRInhOYsu
My 1st first author paper is published @FEBSJournal:
We show how Reg1 & Snf1 regulate the stress-induced relocalization of protein phosphatase-1 to cytoplasmic granules which is mediated by Cdc48 & PP1 regulatory subunit Ypi1.
Thanks to all co-authors!
https://t.co/6m3tT3s9pu