60 y/w with enhancing mass involving the frontal lobe. Satisfies criteria for #glioblastoma, and additionally #MMR protein loss (MSH2/MSH6). This diagnosis should be considered in diffuse gliomas with giant cells, particularly when developing in young patients. But learning that the clinicopathologic spectrum is wider. In this case the giant cells are scant and the patient is in a older age group. #Neuropath #Neuroonc #braintumor
75-year-old man with progressive neurologic deficits and multiple small strokes. Make sure to look carefully at those small vessels!. #intravascular#lymphoma easy to miss. Patient diagnosed on brain biopsy. #neuropath#PCNSL#stroke
Tremendous new resource by Dr. Bob Schmidt @wusm_pathology, a detailed online atlas of neuropathology! Check it out here
https://t.co/MdmwhtEsss
It's a true labor of love by a legendary neuropathologist! #pathology#neuropath#pathtwitter
Look at the explosion of knowledge we've had in diagnosing CNS tumors! Dr. White found me a copy of his 2nd ed. (1993) of the WHO classification of CNS tumors and I compared it to the current one (2021). We need real-time clinical decision support for pathology #pathtwitter
The Knight ADRC and BioFINDER present the most comprehensive look yet at CSF tau phosphorylation in Alzheimer disease. pT217/T217 (%) is better than Aβ42/40 in reflecting amyloid burden; pT205/T205 better reflects tau. #ENDALZ @WUADRC @biofinder_study 🧠
https://t.co/OIvVjGunlD
@UtsWcand@UTSW_NeuroGrads@KonopkaLab Congratulations Amy! You did a fantastic job! So proud of you! This photo of the proud mentor and Dr. Amy is priceless!