Holly Addison

PhD student at MPI Marburg @mpi_marburg🕺 Interested in electron transfer proteins @Rebeleinlab

[Holly Addison @HollyGAddison]

I am excited to share that my first research paper is now available online at @mBio: https://t.co/QgXI5GlUhu. We explore the role of #ferredoxins (Fds) in nitrogen (N2) fixation by #nitrogenases (N2ases), the only enzymes to convert atmospheric N2 into bioavailable ammonia (NH3).

[Max Planck Institute for Terrestrial Microbiology @mpi_marburg]

Paper Alert 🚀! Exciting findings from @RebeleinLab! Two proteins are crucial for electron supply of Fe #Nitrogenase: new targets for improving #biocatalysis in #sustainable #fertilizer and carbon compound synthesis. Check out our press article: https://t.co/MnFIk5vET6

[ChemEurJ: Chemistry - A European Journal @ChemEurJ]

Leveraging spectroscopic & structural approaches - @HollyGAddison, @AJPierik, @RebeleinLab & team obtained new insights into their inner workings of the two-electron transport proteins ferredoxin N and C involved in N2 fixation #openaccess 🔓 https://t.co/X4CeOmFbnI

[Johannes Rebelein @RebeleinLab]

Using spectroscopic and structural approaches we gained new insights into the role of #ferredoxins in N2 fixation. Just published in @ChemEurJ: https://t.co/pbeYoZDNzE! Great work by @HollyGAddison and fantastic excellent with @AJPierik.

[Antonio J. Pierik @AJPierik]

Dear nitrogenase lovers: have a look at our BioRxiv prepublication. Ana Maciel, Jessica Soares, ..., Antonio Pierik and Johannes Rebelein proudly present that Methylthio-alkane reductases use nitrogenase metalloclusters for carbon-sulfur bond cleavage. https://t.co/NAROCqBbVi

[Holly Addison @HollyGAddison]

@miCHRIScopy @RVZ_Wuerzburg @uniwue @ImodLab Congrats!!!!

[Holly Addison @HollyGAddison]

@miCHRIScopy @mbio Thanks Chris!

[Holly Addison @HollyGAddison]

I am excited to share that my first research paper is now available online at @mBio: https://t.co/QgXI5GlUhu. We explore the role of #ferredoxins (Fds) in nitrogen (N2) fixation by #nitrogenases (N2ases), the only enzymes to convert atmospheric N2 into bioavailable ammonia (NH3).

[Max Planck Institute for Terrestrial Microbiology @mpi_marburg]

Paper Alert 🚀! Exciting findings from @RebeleinLab! Two proteins are crucial for electron supply of Fe #Nitrogenase: new targets for improving #biocatalysis in #sustainable #fertilizer and carbon compound synthesis. Check out our press article: https://t.co/MnFIk5vET6

[Holly Addison @HollyGAddison]

@bobelly_ @mbiojournal Thanks so much :)

[Holly Addison @HollyGAddison]

@benhardybristol @mbio Thanks Ben!

[Holly Addison @HollyGAddison]

@mbio I would like to thank the co-authors on this publication, Dr. Timo Glatter and @KaHochberg. Also, a special thanks to my PhD supervisor @RebeleinLab!

[Holly Addison @HollyGAddison]

@mbio Both Fds are excellent targets for bioengineering the e- flux to the Fe-N2ase with aims to further increase the conversion of N2to NH3.

[Holly Addison @HollyGAddison]

@mbio We found that 2 distinct Fds with different redox centres are essential for N2-fixation by the Fe-N2ase, though surprisingly, our results suggest the 2 Fds likely have separate roles in N2-fixation.

[Holly Addison @HollyGAddison]

@mbio We investigate the unknown e- transfer to the Fe-N2ase and tackle the question whether Fds are specific or redundant in the e- transport to the Fe-N2ase in Rhodobacter capsulatus.

[Daniel Schindler @DSchindler_PDR]

Happy to see our Nanopore sequencing workflow for construct validation published. Congratulations @adanramirezro, @CedKB and the one and only Tania https://t.co/qJJieEndRR
Big thanks @MPDL for funding Open Access.

We also pulled together a protocol https://t.co/dZVwzOLUB8

[Holly Addison @HollyGAddison]

@agoldman252 @ProfMaggie @JoffSilberg @biogeochem Congrats!

[Holly Addison @HollyGAddison]

Finally, I would like to thank the co-authors on this publication, Dr. Timo Glatter and @KaHochberg. Also, a special thanks to my PhD supervisor @RebeleinLab. Thanks for reading 😀

[Holly Addison @HollyGAddison]

Our manuscript is now online @Bioarchivepreprint! We explore the role of #ferredoxins (Fds) in nitrogen (N2) fixation via #nitrogenases (N2ases), the only enzymes to convert atmospheric N2 into bioavailable ammonia (NH3) and CO2 directly to hydrocarbons. https://t.co/YJHG5LoBXG

[Holly Addison @HollyGAddison]

In conclusion, we established that 2 distinct Fds with different redox centres are essential for Fe-N2ase mediated N2-fixation. These Fds are excellent targets for bioengineering aiming to further increase the conversion of N2 to NH3and CO2 to hydrocarbons by the Fe-N2ase.