@KatyKray73 Yet, a shit load of tax dollars already goes to Muslim Community, yet they are advertising againest the Christian faith to reduce their funding. Pure evil!
Chemotherapy can speed up cancer spread, Chinese study finds:
'Common treatment can wake up dormant cancer cells, causing the disease to spread from original sites to other organs, team discovers'
"A team of Chinese scientists has found that the spread of cancer from original tumour sites to distant organs can be caused by chemotherapy triggering the awakening of dormant cancer cells.
Their findings shed light on why breast cancer patients can experience cancer metastasis in organs like the lungs despite successful treatment of their primary tumours.
The team also found that the use of specific drugs in combination with chemotherapy could be used to inhibit this process in mice, and a clinical trial is already under way in breast cancer patients.
“We demonstrate that chemotherapeutic drugs, including doxorubicin and cisplatin, enhance proliferation and lung metastasis of dormant breast cancer cells,” the team wrote in a paper published in the peer-reviewed journal Cancer Cell on July 3.
“This study provides direct evidence of dormancy awakening and reveals a mechanism underlying [the] detrimental effect of chemotherapy on metastasis, highlighting potential strategies to improve cancer treatment.”
Researchers in the United States previously found that high doses of radiation therapy to treat cancer could paradoxically lead to the growth of metastatic tumours.
Many patients who undergo chemotherapy to treat primary tumours, the original tumour site in the body where cancer cells first start to develop, can have cancer relapses in other organs even after complete primary tumour regression.
This has led to research into whether chemotherapy can have a similar paradoxical effect, in which it both treats primary tumours and triggers cancer metastasis.
“It is postulated that the reactivation, or awakening, of dormant disseminated tumour cells (DTCs) in distant organs results in metastatic relapse after the asymptomatic period,” the team said.
Studies have shown that disseminated cancer cells, which travel from primary tumours to sites in the body, can be found even during the early stages of primary cancer formation, according to a news release by the Chinese Academy of Sciences (CAS).
These cells can stay in a dormant state for years, during which they do not grow and multiply, allowing them to evade chemotherapy.
Researchers have previously identified molecular mechanisms that regulate metastatic relapse and disseminated cancer cell dormancy. However, it has not been clear whether metastasis results from the reactivation of dormant cells or the growth of rare, non-dormant disseminated cells.
“Understanding the exogenous causes of DTC awakening will help disease management of cancer survivors, offering opportunities to prevent and interrupt metastatic relapse after initial therapies,” the researchers said in their paper.
To study this, the team led by Hu Guohong, a professor at CAS’ Shanghai Institute of Nutrition and Health, along with researchers from Fudan University and Qilu Hospital of Shandong University, developed a cancer cell dormancy tracing approach.
The team confirmed that chemotherapy-induced reactivation of dormant cells from breast cancer could lead to metastatic relapse in the lungs of mice.
Their findings demonstrated that the “awakening of dormant DTCs, but not accumulation of pre-existing proliferative DTCs, is responsible for metastases induced by chemotherapy”.
Chemotherapy induces senescence – an accelerated state of ageing in which cells stop multiplying and release inflammation-causing chemicals – in specialised connective tissue called fibroblasts.
The team found that senescent fibroblasts release proteins that cause immune cells called neutrophils to form weblike formations, called neutrophil extracellular traps, which change the environment in the lung into one that helps dormant cancer cells restart their growth."
BREAKING: The Australian government is using the Bondi crisis to wheel in the most restrictive anti free speech laws this country has ever seen. These will not be used to stop Islamist terror and hate. They will be used as they are being used in the UK… to stop people saying anything at all that might be deemed to be “hateful” to someone. This is an abomination to our very basic human rights and civil liberties to disagree and dissent.
“I sacrificed my life to secure this country's freedom and its freedom of speech — and now you arrest people for words while turning a blind eye to crimes committed by invaders. You are a disgrace to your uniform and you are an insult to mine.”
@TimjboAU It's an agenda and they will do whatever it takes to implement it!
It failed in India because it was hacked and it's failing in China with people becoming homeless.
You can fight back!
"If multiculturalism cannot coexist with free expression, it cannot coexist with democracy—and therefore, it cannot coexist with Australia. Persisting with it amounts to a direct assault on the nation and its people."
https://t.co/MWQRZ9J0NR
Bovaer Scandal in Denmark
The enzyme inhibitor drug Bovaer has been mandatory for use in Danish cows since October 1st.
Now, many cows are collapsing, and some have had to be euthanized.
> “We have so many people calling us, distressed about what’s happening in their herds.”
> “In several cases, farmers have tried removing the substance from the cows’ feed and found that the animals recovered. When they later reintroduced the substance, the problems returned.”
There were always good reasons to be more cautious about Bovaer, as described in the quoted tweet.