Happy Sunday to all! This morning, we are excited to share Chase’s work developing a simple, scalable method to assemble 100s-1000s of custom genes from oligo pools using standard lab tools! (Small 🧵 below)
Happy to share our paper in @NatureSMB, led by @uriellopezs and Lachlan Munro. We are studying how the antidepressant vortioxetine acts on serotonin 5-HT3 receptors in rodents and humans.
https://t.co/msmgml3X2T
Very excited and proud to see the first manuscript of the Wild Team on bioRxiv. If you have ever wondered how the long heparan sulfate polysaccharide chains on the human cell surface are generated, check out our cryo-EM structure of the EXT1-EXT2 complex: https://t.co/Y2jtahPF0J
🦠🥼🧪 JOB ALERT 🇫🇷🔬🇪🇺 Join us for an exciting 2-year post doc position !
“Structure function study of a tripartite efflux pump from the ABC superfamily, in its lipid environment”, spread the word !
https://t.co/dfvhzN0Rhq
https://t.co/Knpp2LdLZg
https://t.co/IBLQzd2WRD
The probability of any receptor being a drug target for COVID, over time, tends towards 1.
It took 1.5 years but finally my beloved serotonin 5-HT3 receptor is added to the list... 😁
Please RT: @Caillaud_MC and myself are looking to hire 4 postdocs and 1 PhD student in the frame of ANR and ERC funded projects to work on membrane lipids and development @RDPlab @ENSdeLyon
live imaging, super-resolution, single molecules, optogenetics
https://t.co/WnVjUJ9B1l
I am happy to announce that we have funding for a new postdoc position in my lab. If interested, please see ad
Postdoctoral Fellow in Neuroscience lab job with Icahn School of Medicine at Mount Sinai New York City, New York (US) https://t.co/DzisWcEXNX #jobs
I am happy to see our paper in Press! This work provides evidence of a cross-talk between SLC20A2 and XPR1 in the regulation of cellular phosphate homeostasis. Alteration of this interplay likely contributes to Primary Familial Brain Calcification.
https://t.co/g8x3hcALTY
First preprint (and tweet)!
Binding of palonosetron + other antiemetics to the serotonin 5-HT3 receptor. CryoEM and simulations.
https://t.co/gKkGIbwWyg
(Please note: same topic, last summer, similarly cool granisetron-bound structure from @Chakrapani_lab@sandipbasak21)