Dave Hughes

Assistant Professor | @AM_OMRF | Skeletal Muscle, Atrophy, Aging, Protein Quality Control (PQC) | Views my own | 📚💪🏼🇬🇧 #myotwitter

[Dave Hughes @HughesDC_Muscle]

Final Version of our article on UBR-box E3 ubiquitin ligases, protein synthesis and skeletal muscle size now online 🚨 | @AJPCellPhys @CraigAGoodman1 @DrAdamPSharples |

https://t.co/mi4R2NZ6Vd

Review in this area recently published here: https://t.co/rbpjBc7q6I

#Myotwitter

[Harrison Finn, PhD @HarrisonFinn]

In Memoriam: V. Reggie Edgerton - Lieber - The Journal of Physiology - Wiley Online Library https://t.co/ei2DLm4Uxf

[Craig A. Goodman @CraigAGoodman1]

Multicellular senescence impairs skeletal muscle recovery following disuse in aging
https://t.co/anPdeb8yYD

[OMRF @OMRF]

We welcomed two new Board Directors and awarded multiple scientists for their research at yesterday's spring Board meeting.

Read more: https://t.co/VV23QNy348

[Dave Hughes @HughesDC_Muscle]

MyoRep: A Novel Reporter System to Detect Early Muscle Atrophy In Vitro and In Vivo | #myotwitter
https://t.co/fknajVvXBX

[Simone Porcelli @PorcelliSimone]

Finally out the data we collected in the over90 200m world record holder. Read if you are interested in knowing how aging can be modified by lifelong training #longevity #physiology
https://t.co/BdzZq34LLT

https://t.co/VmfjqAwX6n

[Agingdoc🩺Dr David Barzilai🔔MD PhD MS MBA DipABLM @agingdoc1]

The rapamycin sTORy: 50-year journey from Easter Island to the frontiers of biology and medicine

https://t.co/Jn67QrGVi6

[Dave Hughes @HughesDC_Muscle]

Drp1 regulates mitochondrial health and controls skeletal muscle mass through the Erk1/2-Nur77 pathway #myotwitter

https://t.co/fXUOXjitfw

[AJP-Cell Physiology @AJPCellPhys]

Brand new #ArticleinPress today! Overactive PDGFRα and PDGFRβ promote distinct phenotypes of skeletal muscle #fibrosis and stiffness, with PDGFRβ also driving #muscle growth (Mariola Gimla et al. @OMRF):

https://t.co/wKdpH2Jmzy

[Gilles Gouspillou @GGouspillou]

The final version of our latest paper is now online: BCL6 regulates skeletal muscle mass and mitochondrial bioenergetics. https://t.co/JWy30hxcnN

[OMRF @OMRF]

OMRF's Dr. Sue Bodine was elected and installed as the society’s 99th president. With nearly 10,000 members, the @APSPhysiology is the world’s largest association of physiologists.

Read more: https://t.co/fPdxglESpj

[Craig A. Goodman @CraigAGoodman1]

Mitochondrial protein import stress causes lysosomal damage and progressive tissue atrophy
https://t.co/dSLs96eIoq

[SofiaZaganelli @SofiaZaganelli]

5.5 years and two babies later, my postdoctoral work is finally out in Cell today! So very grateful to everyone who made this possible.

Nuclear envelope budding enables export of large transcripts in muscle... https://t.co/cIDGyUvNlA

[Craig A. Goodman @CraigAGoodman1]

It was a privilege to have played a role in this groundbreaking work of @Ma_Jochem, @cobbold_simon & David Komander showing in vivo ubiquitination of glycogen & metabolites in tissues, incl. skeletal muscle, that re-writes the textbooks. @WEHI_research
https://t.co/bCC19mtJwc

[Centre for Muscle Research @UniMelbCMR]

Congrats to @Ma_Jochem, @cobbold_simon & David Komander for their new Nature paper, "Ubiquitination of glycogen and metabolites in cells and tissues", that also involved the CMR's @CraigAGoodman1 & @pgregorevic #myotwitter #ubiquitin @WEHI_research
https://t.co/k5sxgVTcdl

[Dave Hughes @HughesDC_Muscle]

Looking forward to being at #APS2026 later this week 👍🏼��🏼‍🔬

[American Physiological Society @APSPhysiology]

This week at APS: #APS2026 starts this week!

➡️Register (there’s still time!): https://t.co/tR5WUUcPvQ
➡️Mobile app: https://t.co/2CI9XJO0nK
➡️Program: https://t.co/y9VwCkATei
➡️Game changers: https://t.co/l5VhwsJ0q5
➡️More https://t.co/y9VwCkATei

#WeArePhysiology

[Craig A. Goodman @CraigAGoodman1]

Autophagy selectively clears ER in TNF-α-induced muscle atrophy
https://t.co/hetGa9XJwn

[Gilles Gouspillou @GGouspillou]

Excited to share our new paper showing that BCL6, a transcriptional repressor, regulates skeletal muscle mass, mitochondrial bioenergetics & may mediate endurance training adaptations.
Fantastic collaboration with @MinnaWoo, @JeanPhilippeLG2 & many others!
https://t.co/nIlbfGlIyf

[Craig A. Goodman @CraigAGoodman1]

Single-Nucleus RNA Sequencing Reveals Muscle Fiber Cell Heterogeneity During Human Skeletal Muscle Aging
https://t.co/FNZMPfYJ7i

[Hailey A Parry, PhD @parry_hailey]

New paper dropped! Very excited to share this review I started during COVID. It made its home in my graduate school files for a few years before @phc_mesquita, @Wendy_R_Hood, @kangnianyap, and I got back to it. Check it out!
https://t.co/2lVURGMe8H

[Dave Hughes @HughesDC_Muscle]

It’s great to see this success for Dr. Johnson and support she has received. It also reaffirms the vital role that scientific societies can play in training the next generation of scientists 🥼🔬🧬👏🏼👏🏼👏🏼

[OMRF @OMRF]

OMRF postdoctoral fellow Dr. Charmain Johnson received the @American_Heart Career Development Award, which comes with a research grant funding her study of an autoimmune disease that sometimes results in organ failure.

🫀 Read more: https://t.co/4idhPEY77Q