Humayun

Passionate about understanding ways of dying #celldeath & pattern recognition receptors!!! #InnateImmunity #StrucutralBiology 🇵🇰🇰🇷🇩🇪🇺🇸

[Venkat Giri Magupalli @MagupalliVenny]

Our new study: ASC directly recruits pro-IL-1β for maturation, revealing a new checkpoint in inflammasome signaling. Congrats to Giti Saha and all collaborators! @WuLabHarvard @Huminature @ismails2005 @L_Luchsinger | PNAS https://t.co/acTqkkGRgd

[Prof. Hao Wu @WuLabHarvard]

Ever wondered why only inflammasomes that use ASC, but not those that do not use ASC, can mature IL-1β? ASC helps to recruit pro-IL-1β to ASC for caspase-1 processing! See: "Inflammasome adaptor protein ASC is a mechanistic checkpoint in IL-1β maturation" https://t.co/2wWDusQMaJ

[Eric Topol @EricTopol]

When 2 life science discoveries converge: solving a ~3 decade mystery of extraordinary longevity and healthspan + an essential cell danger sensor
And related ongoing clinical trials!
https://t.co/w57FVPiuN1

[Humayun @Huminature]

"Science is the greatest equalising force in the world" - Omar Yaghi

[The Nobel Prize @NobelPrize]

BREAKING NEWS
The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”

[Ardem Patapoutian @ardemp]

Whaaat? “Their team has now found dozens of even bigger proteins, including what might be the longest ever: an 85,000-amino-acid behemoth.” https://t.co/BaA7N4XQyn

[Humayun @Huminature]

A must read by all the academics #gaza https://t.co/Cd8DS5kNWI

[Roland Dunbrack 🏳️‍🌈 @rolanddunbrack.bsky.social @RolandDunbrack]

Demis -- I think AlphaFold3 is really exciting. As Reviewer #3, I got great results from the server. I tried hard to get @Nature to urge you to release the code but was unsuccessful. I did not get it for re-review so I don't know if you responded. So why no code? @GoogleDeepMind

[Prof. Hao Wu @WuLabHarvard]

I am excited to share with you the Wu Lab Reunion video by Kara @jf033! 27 featured structures and the 27-year journey! Seeing trainees from all over the world doing the best science is the ultimate reward as a mentor! I am proud!

[Humayun @Huminature]

@taniasaeed Btw what England or any other western country does when there are illegal immigrants?

[Humayun @Huminature]

Time out for western academics for not speaking about the atrocities of #Gaza

https://t.co/nFxQt1qn49

[Dhruv Chauhan @Dhruvchauhan241]

This fantastic story is out on structural analysis of NLRP3 inflammasome activation. Happy to be part of it! Please check it out!

https://t.co/Oke4KQsJXi

[Humayun @Huminature]

Alphafold as an exceptionally useful hypothesis’ only!! https://t.co/RZbsm5fNrq

[Humayun @Huminature]

Cornel West!!!

[Abier @abierkhatib]

Goosebumps, head to toes, literally head to toes.

What a legend!!

#Gaza

[Humayun @Huminature]

Sorry to hear the price you paid for speaking out the truth and for not taking side of the oppressors @mbeisen

[Michael 英泉 Eisen @mbeisen]

I have been informed that I am being replaced as the Editor in Chief of @eLife for retweeting a @TheOnion piece that calls out indifference to the lives of Palestinian civilians.

[Humayun @Huminature]

@BobbyHollings I wonder how they got away with "Here we identify ubiquitously expressed endogenous thioredoxin (TRX) as a binder of NLRP1 and a suppressor of the NLRP1 infammasome" in reviewing process? I'm curious about the "reviewers"

[Humayun @Huminature]

A concise summary of taxic labs!! Unfortunately, many renowned professors promote this toxicity in their labs.

[Jadson Jall, PhD @JadsonJall]

Colleagues and fellow researchers,
Our community must be aware of these red flags, as they hinder our research's progress and quality and impact the mental and emotional well-being of our brightest minds.
See the full post in my newsletter: https://t.co/bRkSlJdzjj
#LabCulture #ResearchIntegrity #HealthyWorkplace #ScienceMatters

[Humayun @Huminature]

@JPLab_ @GeneCenter_LMU @EdinburghUni @SBSatEd @WTcell @jp_arulanandam Definitely!

[The Nobel Prize @NobelPrize]

As a 14-year-old boy, Abdus Salam, gained the highest marks ever recorded for the Matriculation Examination at University of the Punjab.

In 1979, he shared the #NobelPrize in Physics for contributions to the electroweak unification theory.

Learn more: https://t.co/Q1tmaJQLBq