JC Ott

ID RPh trying to preserve our super friendly bugs in Big Sky country

[Pharmageddon: Bugs vs Drugs @PharmageddonG]

📢Final week of the Kickstarter!

Last 7 days to get a copy of a fun new card game to learn and teach infectious diseases!

https://t.co/AXWYedz8Pl

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

Updated nomenclature of common Candida species
Add Candida auris ⏭️Candidozyma auris.
#IDXposts #bookmark https://t.co/Fd6RPPh424

[Lisa Dumkow @LisaIDpharmD]

‼️Just shared at #IDWeek2025, our findings are now published in @OFIDJournal comparing cephalexin to cefdinir for uUTI in females. Spoiler: cefdinir was the only independent risk factor associated with/failure. Poor urinary PK = ⬆️failure. Let’s stop Rx’ing cefdinir for UTI! 🛑💊

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

🆕💫 ENDO-ORAL study
switching from IV to oral antibiotic therapy in IE was effective, including in patients not eligible in recent RCTs eg POET, advocating that it could be more widely performed than currently suggested.
@BradSpellberg @DrToddLee
#IEWiki https://t.co/1Ht6mzlZjV

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

🆕🔥Clinical Insights @JAMAInternalMed
When Can a MRSA Nares Swab Guide Antibiotic Stewardship?
What the Nose Knows #idxposts
https://t.co/sHoW6nmJPO

[Bug Pharmacist 💊🧫 Tim Gauthier @IDstewardship]

🧫 Acinetobacter is such a PIA

“This mini-review examines the available antibiotics that exhibit activity against these organisms and provides guidance as to which cultures are relevant and how to treat active infections. Antibiograms describing resistance mechanisms and the minimum inhibitory concentration (MIC) are essential to determine which agent or combination of agents should be used after confirmation of infection, utilizing clinical parameters and biomarkers such as procalcitonin.”

https://t.co/tMfz1wZHd7 in ❤️ CMR @ASMicrobiology @JClinMicro

[Brad Spellberg @BradSpellberg]

@Absteward has reported that BALANCE is now published, so the Table is now updated! GNB bacteremia is now listed as Bacteremia (non S. aureus). Neary 5,000 patients have now been randomized to 1 vs. 2 Constantine Units for non S. aureus bacteremia.
https://t.co/1oaAT6Cybb

[JC Ott @IDRPhJC]

@accpinfdprn @RosandichThomas Zoom says the room has reached capacity ☹️

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

Ocular infections are common and range from mild to vision threatening
🆕️🔥State-of-the-Art Review: Ocular Infections, A primer for ID clinicians
Infectious Conjunctivitis
Infectious Keratitis
Endophthalmitis
Uveitis
Retinitis
#idxposts https://t.co/iQx1xlunv9

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

🔥🔥Just published🔥🔥
Our NEW @Wiki_Guidelines @JAMANetworkOpen
A stellar cast of auth🌟rs @zacroBID @amenalor @BradSpellberg @DrToddLee @DrEmilyMcD
Guidelines for the Prevention Diagnosis,and Management of Urinary Tract Infections in Pediatrics& Adults
https://t.co/zakvuleqpU

[Paul Sax @PaulSaxMD]

Gathering with a bunch of fellow ID geeks (that is, people like me) last week inspired this deeper look at the PCP vs PJP controversy for Pneumocystis jirovecii pneumonia.

It’s only Part 1, so a real cliffhanger. Enjoy. https://t.co/RgMfUQ5yVy

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

Excellent 🆕️⚡️⚡️Editorial @yourICM
Invasive fungal infections in non-neutropenic patients #idxposts
https://t.co/n5FxmQdDfc

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

🔥BALANCE RCT🔥 results #IDWeek2024
3,608 patients
74 hospitals in 7 countries
A 7-day course of antibiotics for hospitalized patients with bloodstream infections is just as effective as a 14-day course,Both treatment durations demonstrated similar 90d mortality & relapse rates.

[Bryan White @bryan_p_white]

Last session of the day on influential pubs. #IDWeek2024

[Michael Calderwood, MD, MPH @CalderwoodMD]

Poster 87 at #IDWeek2024: When @StanfordMed increased percentage of patients with PJI and DFI who were discharged on oral antibiotics from 25% to 69%, there was no difference in treatment failure with a reduced LOS, fewer central line adverse events, and more home discharges!

[Michael Calderwood, MD, MPH @CalderwoodMD]

STOP-CDI Trial from UPenn presented at #IDWeek2024: Solid-organ transplant, autologous stem cell transplant, CART, and leukemia admissions screened for C diff colonization. Triggered contact precautions and prophylactic PO Vanco. 79% reduced odds of HO-CDI (and reduced LOS)!

[Brad Langford @BRxAD]

Dr. Nick Daneman presents the much-awaited BALANCE trial presented at #IDWeek2024. Of 3608 randomized, 90-day mortality occurred in 261 (14.5%) patients receiving 7-day and in 286 (16.1%) receiving 14-day treatment (absolute difference -1.6% [95.7% CI -4.0 to 0.8])

[Saira Butt @SAIRABT]

#idweek2024 beta lactams for staph aureus bacteremia #SAB by Daniel Chastain

[Michael Calderwood, MD, MPH @CalderwoodMD]

I love these two slides on the evidence for combination therapy in persistent MRSA and MSSA bacteremia. References in footer of each slide. #IDWeek2024

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

🆕️⚡️⚡️Systematic review and meta-analysis* did not demonstrate a significant difference in the rates of CMV relapse among solid organ transplant recipients who received or did not receive secondary anti-viral prophylaxis after treatment of CMV disease
https://t.co/ElkeYBgLhS