patho

Pathology resident, NOS

[patho @INA_patho]

@ZemplenPataki @UMichPath Prostatic acinar adenocarcinoma DD/ post atrophic hyperplasia
I'd rely on ihc

[Janira Navarro @Janiranavarro]

Pleomorphic adenoma
***Practical issues***

The parotid gland is rich in facial nerve branches, so the surgeon must carefully peel the tumor away from them

✅ If the inked margin is smooth and undulated, this is not a positive margin (see Pic 1)
Sign out the case as in Pic 2

❌ If the margin appears chewed up or irregular, this is a positive margin (see Pic 3).
Sign out the case as in Pic 4.

Dr. Lewis #JobPrepBootcamp #NIPCAP #pathology #PathX #pathtwitter

[Cytopathology.org @cytopathology]

🚀 Discover CytoJobs, the official ASC Career Center! 🔬

💼 Your future in cytopathology begins here.

🔍 Explore career opportunities, 📄 upload your resume/CV, and 🔔 stay informed with personalized job alerts.

🌐 https://t.co/4s6PttE13R

#CytoJobs #Cytopathology #Cytologist

[Janira Navarro @Janiranavarro]

Before making a diagnosis of invasive breast cancer in a core needle biopsy, be sure it is truly a primary breast tumor, particularly in the era of neoadjuvant chemotherapy

Metastatic serous carcinoma and metastatic melanoma to breast (pic 1)
Metastatic lung adenocarcinoma (pic 2)
Metastatic medullary thyroid carcinoma (pic3)

Of 2423 TNBC submitted to Caris for molecular profiling over 19 months there was a misdiagnosis of TNBC in 73 cases (3%). Half of those cases were non-small lung cancer (data submitted for publication)

Dr. Schnitt #USCAP2026 #pathology #PathX #PathTwitter

[Zemplén Pataki, MD, PhD @ZemplenPataki]

Spine. What is your diagnosis? 🔎

Poll below 🗳️👇

#PathPuzzle 🕵️‍♂️
@UMichPath #Pathology #PathX #PathTwitter
@CraigHorbinski

[Dr Kamlesh Darji @DrKamleshDarji1]

https://t.co/GNzFal6bLj

[Dr Kamlesh Darji @DrKamleshDarji1]

Algorithmic approach to the Renal Biopsy #PathX

[Janira Navarro @Janiranavarro]

New entities in soft tissue pathology

***FET-CREB fusion sarcomas***

Variable histology with epithelioid/round cells showing an odd combination of multiple aberrant markers (CK, EMA, MUC4, ALK, CD30, synapto , etc.) is valuable for screening FET-CREB sarcomas

Half of cases are intra-abdominal
Wide age range
Highly aggressive

Will be included in the upcoming BST WHO book

FET-CREB is an umbrella term for fusions between FET genes (mainly EWSR1, sometimes FUS) and CREB family transcription factors (CREB1, ATF1, or CREM)

Pitfall: Angiomatoid fibrohistiocytoma (AFH) and FET-CREB sarcomas have a similar genotype, but morphology differs and, most importantly, AFH mortality is >1% versus >50% in FET-CREB sarcomas

Dr. Agaimy #USCAP2026 #pathology #PathX #PathTwitter

[Everyday_Pathology @Pathology_Xever]

Watch past recordings from GAP webinars here: https://t.co/yoMPxgcRet

[Janira Navarro @Janiranavarro]

Smooth muscle lesions of the lung

- Benign metastasizing leiomyoma (pic 1)
- Metaplastic smooth muscle nodules (pic 4, not uncommon)
- LAM (lymphagioleiomyomatosis): Pic 3, tends to be more cystic than cellular
- Metastatic leiomyosarcoma
- Primary leiomyoma of lung: Rare

Other spindle cell tumors of lung
- Metastatic endometrial stromal sarcoma of uterus
- SFT, IMT, schwannoma , etc

Dr. Yi #USCAP2026 #pathology #PathX #PathTwitter

[Amer Swid @AmerSwid]

Reactive mesothelium vs malignancy.....subtle differences, BUT major consequences!!!

[Dr. Arkadip MD @pathognosis22]

The #Bethesda System - cervix - squamous cell #TBS #cervix #LSIL #HSIL #SCC #pathology #pathognosis #cytology

[Fouad Boulos @fouad_boulos]

This is a superficial breast lesion in a man. What is your differential?

I am stumped.

#breastpath #dermpath

[Charlie Herndon @DrCycloPath]

#PathQuiz 🔬#DermPath

A) Basal cell carcinoma
B) Spiradenoma
C) Sebaceoma
D) Merkel cell carcinoma
WSI https://t.co/yArVLu7wIo

[Janira Navarro @Janiranavarro]

Thymoma is an epithelial neoplasm
Best IHC for thymoma: CK AE1/AE3 and TdT
Why TdT?
-TdT stains thymic lymphocytes. -Thymoma is a tumor that try to resemble how normal thymus grows, that's why it carries TdT positive lymphocytes and form lobules

Thymomas vs thymic carcinomas
-Thymomas are positive for TdT lymphocytes and negative for CD5 and CD117
-Thymic carcinomas are positive for CD5 and CD117

Dr. Mukhopadhyay CCMPS #pathology #pathologists #pathtwitter #NIPPathX #pathresidents #PathX

[Jose Fernando Moura, PhD @FernandoOnco]

https://t.co/FhQQ0ZxKjk

Educacional book 📕@ASCO unveiled
#tnbc #breastcancer is out

@Dr_Oncologista @OncoAlert @OncoReporte @Larvol

[patho @INA_patho]

@DrCycloPath Are we allowed to sign adenosquamous carcinoma of lung from cytology? I thought it was not recommended?

[Charlie Herndon @DrCycloPath]

#PathQuiz 🔬🫁 #PulmonaryPath

A) Large cell neuroendocrine carcinoma
B) Diffuse large B-cell lymphoma
C) Small cell lung carcinoma
D) Squamous cell carcinoma

#Pathology #Cytology #CytoPath #ThoracicPath

[Gerônimo Jr. @GeronimoJrLapac]

A nice example of Nevus sebaceus of Jadassohn.

#dermpath #pathology

[Henry C Fung| MM, lymphoma, leukemia & CART @HenrychihangFu1]

Defining T-cell lymphoma doesn’t have to be complicated.

Start simple:

🔴 CD30+ → ALCL
 ALK+ vs ALK− (DUSP22 / TP63 / triple negative)

🔵 If not → check TFH markers
 PD1 / ICOS / CXCL13 / BCL6
 → often behaves like autoimmune disease

⚪ Only then → PTCL-NOS

🧬 Biology matters:
ALCL ≠ one disease
TFH = TET2 / DNMT3A / RHOA

👉 “CD30 first. TFH second. NOS last.”

#lymphoma #Hemetwitter #Medtwitter