The role of IUS in assessment of IBD patients is expanding. Pleased to finally publish this work with @IBDmedicaldoc@ArdalanZaid. Infliximab Trough Levels Are Associated With Transmural Sonographic Healing in Inflammatory Bowel Disease https://t.co/TfCAzbT8Tc
Finally, the #Stardust#intestinalultrasound substudy is online. "IUS response and transmural remission rates progressively increased through week 48 with ustekinumab therapy, most pronounced in the colon and biologic-naïve patients": https://t.co/97YbLQyhBr @BowelUltrasound
Introduction to advanced therapies in IBD
My talk to the surgeons @ACPGBI today @eicc
🧵 covering:
• therapeutic targets
• treatment strategies
• therapeutic ceiling
• early effective therapies in Crohn's
• the pros and cons of anti-TNF
• new small molecules for UC
https://t.co/vzIJDMRgrz Sonographic healing is important, we found it was associated with reduced risk of medication escalation, corticosteroid use, hospitalisation and surgery in people with Crohn’s disease in clinical remission. @IBDmedicaldoc@aysha_h_alani
#IUS gold: ileal #Crohns pt well on IFX. Flu sx for 2/7 (-covid) & CRP 270. Improved for day then diarrhoea and abdominal pain. POC IUS by expert @RoseVau76322963 found NEW severe sigmoid dx with bwt 9mm, hyperaemia and fat hypertrophy. Now to flex sig and stool mcs to get dx!