Reperfusion injury cannot be completely prevented, but its severity may be reduced through:
1. Controlled reperfusion – Gradual restoration of blood flow with adjustments in pressure, oxygen, calcium, and pH to limit cellular injury.
2. Ischemic preconditioning – Brief episodes of ischemia before a prolonged insult, activating endogenous protective pathways.
3. Pharmacologic therapies – Antioxidants (e.g., vitamin C, N-acetylcysteine), calcium channel blockers (e.g., verapamil), sodium–hydrogen exchange inhibitors (e.g., cariporide), and anti-inflammatory agents may reduce oxidative stress, calcium overload, and inflammation.
4. Hypothermia – Tissue cooling lowers metabolic demand and attenuates reperfusion-related damage.
5. Ischemic postconditioning – Brief interruptions of blood flow at the onset of reperfusion to reduce oxidative and inflammatory injury.
In practice, controlled reperfusion and hypothermia are the most established strategies, while many pharmacologic approaches remain investigational.
The first shock of my life as a Nigerian while growing up was when I went to some of my friends’ houses and I discovered that they used to thank their parents after eating.
So this Dr , a neurosurgery resident is caught up in the wrong crowd basically operating on gang members. Now the Boss has a brain haemorrhage and is at the hospital she is resident at . The gang said if the Boss does her family will be wiped out cause she is the lead surgeon
So this Dr , a neurosurgery resident is caught up in the wrong crowd basically operating on gang members. Now the Boss has a brain haemorrhage and is at the hospital she is resident at . The gang said if the Boss does her family will be wiped out cause she is the lead surgeon
Reading a book about 3 medical residents in the US . Can’t help but notice some inconsistencies .
The book has moved forward 4 years and one of the residents in internal medicine is still in residency and worse still is making mistakes with dosing of medication
Reading a book about 3 medical residents in the US . Can’t help but notice some inconsistencies .
The book has moved forward 4 years and one of the residents in internal medicine is still in residency and worse still is making mistakes with dosing of medication
How can you popularise Mental health in Nigeria? By this I mean taking therapy seriously. I meet people that seem like they can benefit from it.
People want to talk , not just to psychiatrists. How do we undo this stigma.