The official website for the tRNA2024 Conference has been updated! You can now find the latest presentation schedules, session details, and notification to oral/poster presentation. Stay up to date and plan your presentation:
https://t.co/eE11ZOb3xl
#tRNA2024
That's what the pluripotent stem cell field has been waiting for. Own cells, reprogrammed to iPSCs; differentiated into insulin-producing cells, and translanted back into patient, effectively curing type-1 diabetes! One patient. One year. But a tremendous proof-of-concept.
We are looking for a highly motivated PhD student to explore molecular mechanisms of protein synthesis using fast kinetics and cryo-EM. Pls share the link or apply! https://t.co/mt49j4OODI
At Tevard, we're devoted to improving the lives of people with severe genetic diseases like Duchenne muscular dystrophy (DMD). In honor of #WorldDuchenneAwarenessDay, learn more about DMD, and see how you can help raise awareness: https://t.co/UKijOZrAac #WDAD24
Preprint alert in collaboration with @fraser_lab !
We identify that deleting GidB, a 16S rRNA methyltransferase, acts as an "automatic braking system" for mistranslation!
Ribosomal RNA methylation by GidB modulates discrimination of mischarged tRNA https://t.co/3nFkwBfTNV
We're looking forward to the upcoming RNA Leaders USA Congress. Tevard CEO, Daniel Fisher, will give a presentation on our work to pioneer novel tRNA therapeutics and how our platform is enabling us to advance our pipeline. See the full agenda: https://t.co/hBoaOHpeQs #RNALeaders
We report many proteins not predicted by the genetic code.
They are stable & abundant O( 10³ ) copies / cell.
Generative mechanisms include codon-anticodon mismatches & RNA modifications.
Their abundance depends on codon frequency & protein stability.
https://t.co/lAxvulC4zx
Single-cell proteomics helped answer a fundamental question in development:
The molecule mechanisms of symmetry breaking in early mammalian development.
A great collaboration with @MZG_Lab led by @aleks_petelski & @LIwamotoStohl.
How to repurpose a #tRNA enzyme into a global stress sensor? Co-led by @CharlesBNader, Swati Gaikwad, Soheila Bahmanjah, w/ Alan Hinnebusch lab, in
@PNASNews, we describe how stress kinase Gcn2 adopts and molds Histidyl-tRNA synthetase as a regulatory hub. https://t.co/1IjEEPuGJ6
@JanUlrikDahl1@IllinoisStateU@ISUResearch Awesome Jan! It not only rains on your street, it poors - hsppy for you! Looking forward to seeing you soon in HH and catching up :)
I am very proud of the superstar postdoc @Yang_Haojun_01, who discovered how to translation control underlying fasting and ketogenic diet in health and cancer.
https://t.co/Jd2hXw2Dn6
Happy (t)RNA day! #RNADay
Thank you to our first author baker Vale @Vblancoca - our terrific guest from @jptosar lab - who orchestrated the baking process.
Happy #RNADay! 🎉
Celebrating in Germany with the incredible scientists/bakers at @IgnatovaLab
Check out our entry for the @RNASociety cake competition! 🍰🔬
We hope sharing our creation here is as welcomed as uploading a paper on @biorxivpreprint🤞
@jrRNAscientists
The time to think and inquire are precious.
Inquiring means to contemplate a problem without needing an immediate answer, to sit in the unknown long enough that different kinds of answers emerge. Important part of the process of discovery.
https://t.co/vWgTsld4uJ