Science Benjamin Wheeler

PhD student in the Ansel Lab @UCSF. Studying T Cell Responses to viruses, cancer, and asthma.

[Science Benjamin Wheeler @ImmunoBWheeler]

🧵So excited that my thesis work is out for public viewing @biorxivpreprint today!! So thankful to everyone involved: Ansel Lab Members Didi Zhu, @Cil_MunSandoval, John Gagnon, & Simon Wong & our collaborators @racheldebarge, @SpitzerLab, & @MarsonLab (1)
https://t.co/Q9I9lK3O1F

[Waggoner Lab @LabWaggoner]

The lncRNA Malat1 inhibits miR-15/16 to enhance CTL activation and memory @eLife @MarkAnsell
@ImmunoBWheeler
https://t.co/PheM9pAA3D

[Science Benjamin Wheeler @ImmunoBWheeler]

You can now find this pre-print reviewed @eLife 🤓😄 huge thanks to the editors and reviewers who took the time to evaluate our work!! While the reviews took some time, I am very pleased with the new model. Look for our revised manuscript, coming soon! https://t.co/vJS0rIqY35

[Science Benjamin Wheeler @ImmunoBWheeler]

🧵So excited that my thesis work is out for public viewing @biorxivpreprint today!! So thankful to everyone involved: Ansel Lab Members Didi Zhu, @Cil_MunSandoval, John Gagnon, & Simon Wong & our collaborators @racheldebarge, @SpitzerLab, & @MarsonLab (1)
https://t.co/Q9I9lK3O1F

[Science Benjamin Wheeler @ImmunoBWheeler]

@oaaguilar503 @UCSF @immunox So exciting!! Congrats Oscar!!

[Science Benjamin Wheeler @ImmunoBWheeler]

@evornithology A gud burd

[Science Benjamin Wheeler @ImmunoBWheeler]

Just a few more edits and then the final thesis draft is ready!

[Science Benjamin Wheeler @ImmunoBWheeler]

@JulianeScience @DASuperville Very cool!

[ImmunoDiverse @ImmunoDiverse]

Happy ImmunoDiverse colloquia day! Today we will have our DEI Lecture from Dr. Terrance Mayes @TerranceMayes from @Stanford at 3pm PT time! Please register for this event, and join us in HSW300 or on zoom! #ImmunoDiverse
https://t.co/Jd04tLHfGq

[Rachel Rutishauser (moving to bsky: rrutishauser) @r_rutishauser]

So happy to celebrate Wendy Hung for passing her qualifying exam with flying colors! Woohoo for the Rutishauser Lab’s second PhD candidate! #proudPI @UCSF_EXPM @immunox

[Science Benjamin Wheeler @ImmunoBWheeler]

Another day of thesis writing, another day of strong support from my writing partner

[Science Benjamin Wheeler @ImmunoBWheeler]

@AnjaliEnjeti The airbus A-bee-20

[Oscar A. Aguilar, PhD @oaaguilar503]

¡¡¡1 week away!!! This is a hybrid meeting so if you cannot join us in person, feel free to register!! The @ImmunoDiverse colloquia team has been working hard to bring this together! @TGFBae @mariaglxz @celestegarza55 @Foreverasheley + Dara Fonseca Balladares!!

[Science Benjamin Wheeler @ImmunoBWheeler]

This is awesome! Really gets you thinking about pushing the engineering limits of cell biology.

[Ross Wilson @RossWilsonLab]

I’m excited to share our report - out now in @natBME - of a new approach to CRISPR delivery that is poised to transform the way engineered T cell therapies are manufactured. Visit https://t.co/UmTBpRE8jE for “how to” details. It’s threadin’ time! (1/11) https://t.co/MujT9iue56

[Imran S. Haque (@ihaque@{bsky,genomic}.social) @ImranSHaque]

Tweetorial time! We @RecursionPharma mapped consequences of #CRISPR screening of >17K human genes, found a systematic bias confounding all CRISPR screens, traced its molecular cause, and propose a debiasing algorithm.

[Lisel Hintz @LiselHintz]

Seeking a native Turkish-speaking grad student with media analysis experience to work with me and @JonasDraege as a Research Assistant in May-July. Project on regime-produced videos. Must be able to work in the US, but can work remotely. Please DM your email if interested.

[Science Benjamin Wheeler @ImmunoBWheeler]

@DrBurkePhD @biorxivpreprint @Cil_MunSandoval @racheldebarge @SpitzerLab @MarsonLab Thanks!!

I am currently applying for jobs in industry, so I might not be the right fit. But we are really excited about these Malat1 mice and the idea that this circuit could leveraged to engineer T cell responses. I would be happy to put you in contact with the lab!

[Science Benjamin Wheeler @ImmunoBWheeler]

🧵So excited that my thesis work is out for public viewing @biorxivpreprint today!! So thankful to everyone involved: Ansel Lab Members Didi Zhu, @Cil_MunSandoval, John Gagnon, & Simon Wong & our collaborators @racheldebarge, @SpitzerLab, & @MarsonLab (1)
https://t.co/Q9I9lK3O1F

[Science Benjamin Wheeler @ImmunoBWheeler]

@ZCakirWheeler Thank you!! 😁😁

[Science Benjamin Wheeler @ImmunoBWheeler]

Thesis writing buddy 🐶

[Science Benjamin Wheeler @ImmunoBWheeler]

Its been great working on this project and I have learned so much from all the wonderful people around me @UCSF. Very excited for what this study means about non-coding RNA in T cells and the ability to study similar phenomena using precision genetic tools like we did here. (8)

[Science Benjamin Wheeler @ImmunoBWheeler]

Finally, in vivo we see that memory cells from these Malat1 edited mice have signs of poor activation and decreased survival cues such as IL-2 production and Bcl2 expression. (7)