Infinity Bio Inc.

Leading provider of antibody reactome services. Catalog antigen libraries include human proteome, virome & allergome. Custom library creation also possible!

[Infinity Bio Inc. @InfinityBioInc]

A new Nature Aging study of 5 major cohorts (incl. UK Biobank & ADNI) reveals how APOE2 & APOE4 shape Alzheimer’s risk. Massive, diverse human cohorts are essential for capturing these novel disease mechanisms.

Read more: https://t.co/BivAhSoZh6

[Infinity Bio Inc. @InfinityBioInc]

Most systems immunology data lacks diversity, relying heavily on European ancestry.

The new HHGP-HK Asian reference cohort (1,025 donors) changes that. Diverse human cohorts are essential to address data gaps, validate biomarkers, & discover novel disease associations globally.

[Infinity Bio Inc. @InfinityBioInc]

Exploring the gut microbiome’s role in cancer, Usyk et al. analyzed 674 global melanoma patients. Large, diverse cohorts prove that geographic hurdles vanish when matching microbial fingerprints, unlocking more accurate, personalized immunotherapy.

[https://t.co/BY5u2D96Xx]

#Microbiome #Melanoma #Immunotherapy #Biomarkers #PrecisionMedicine #CancerResearch #Reactomics

[Infinity Bio Inc. @InfinityBioInc]

Precision medicine fails as a "one-size-fits-all." By leveraging the UCLA ATLAS Biobank, researchers integrated EHRs with genomic data from 90,000+ participants to uncover critical disease-gene links in diverse, underrepresented groups, driving new disease associations.

https://t.co/1xCJbcFgor

#PrecisionMedicine #Genomics #HealthEquity #UCLAATLAS

[Infinity Bio Inc. @InfinityBioInc]

How do factors like age and genetics shape our immune defense?

New study used antibody reactome profiling to map the human virome at unprecedented resolution. Reactivity data revealed how our "molecular diary" drives vaccine recall and autoimmune risk.

[https://t.co/QduAjKUhZH]

#Immunology #PrecisionMedicine #AntibodyReactomics #NatureImmunology

[Infinity Bio Inc. @InfinityBioInc]

A new Human Immune Health Atlas published in Nature reveals that immune aging is a non-linear process starting earlier than we thought. By mapping these molecular transitions, we can better tailor vaccines and therapies to biological age, not just the clock.

[https://t.co/JlkKxg23bj]

#ImmuneAgeing #MultiOmics #HumanHealth #Immunology #SystemsBiology #Aging

[Infinity Bio Inc. @InfinityBioInc]

New study in Nature shows immune ageing starts early with T cell reprogramming and GATA3 activity. Adding antibody reactome profiling to these cohorts can reveal the extrinsic viral and environmental triggers of ageing—a vital layer for the multi-omic stack.

[https://t.co/JlkKxg23bj]

#ImmuneAgeing #MultiOmics #HumanHealth #Immunology #SystemsBiology #ImmuneHealthAtlas

[Infinity Bio Inc. @InfinityBioInc]

A massive study of 2,279 brain samples reveals that neurodegenerative diseases share molecular drivers but have distinct subtypes. Integrating antibody reactome profiling could further bridge these gaps by uncovering the immune "history" and auto-reactivity linked to disease.

[https://t.co/aRzAU6IT5g]

#Proteomics #MultiOmics #Neurodegeneration #PrecisionMedicine #CohortOfTheWeek

[Infinity Bio Inc. @InfinityBioInc]

A new study in Nature Medicine reveals that IgG1 producing B-cells and plasma cells are central to anti-tumor immunity. Key findings: clonal IgG1 enrichment in tumors, trafficking between lymph nodes, and targeting of tumor antigens. A T-cell + humoral strategy could transform cancer outcomes.

https://t.co/xGoPnlS6tB

#Immunotherapy #CancerResearch #Bcells #MultiOmics #BCRseq #AntibodyReactome #PrecisionMedicine #Oncology

[Infinity Bio Inc. @InfinityBioInc]

A new @LifelinesNL study of 700+ mother-infant pairs maps dynamics and establishment of the gut virome. Key finding: maternal sharing & early viral diversity are linked to infant immune health and food allergies. Reactomics can now help us unlock how the host response in health and disease.

https://t.co/UldSf8IB82

[Infinity Bio Inc. @InfinityBioInc]

Thrilled to welcome Brian McKelligon as the new CEO of Infinity Bio! Brian is an accomplished life sciences leader and we could not be more excited to have him at the helm. His leadership will accelerate the reach of our MIPSA technology and the inSIGHTs it delivers to researchers worldwide.
#InfinityBio #MIPSA
https://t.co/wTnmnFbPHN

[Infinity Bio Inc. @InfinityBioInc]

New study offers a 25-year molecular map of MS progression. Key findings: EBV is an ongoing driver and sex-specific pathways impact phenotypic outcomes. Large-scale proteomics is vital to uncovering these hidden biomarkers and mechanisms for early intervention.

Read here: https://t.co/PmmHHNACTX

#MultipleSclerosis #MSResearch #EBV #Biomarkers #PrecisionMedicine #Proteomics #MultiOmics #Reactomics

[Infinity Bio Inc. @InfinityBioInc]

Infinity Bio's Katy Shaw-Saliba & Ben Larman just published a new study screening 85 Ig therapy batches against 283,000+ viral peptides, revealing pandemic-driven immune shifts. Discoveries like this begin with decoding the antibody reactome. #AntibodyReactomics https://t.co/hHQqrAeGW8

[Infinity Bio Inc. @InfinityBioInc]

Large-scale study in Nature Communications highlights proteomic markers for lymphoid cancer risk up to 10 years pre-diagnosis. Validating findings across multiple large cohorts like UK Biobank provides broad mechanistic insight enabling early detection and targeted prevention.

Read here: https://t.co/rVaV1YqHnv​

#Proteomics #PrecisionMedicine #Biomarkers #Lymphoma #EarlyDetection #CancerResearch

[Infinity Bio Inc. @InfinityBioInc]

New research uses proteomics to link salivary gland inflammation with serum biomarkers. Key finding: 16 serum proteins correlate with autoantibodies and HLA risk alleles. We suggest adding antibody reactome profiling to map dynamic immune histories and disease drivers / triggers.

Read here: https://t.co/fzgI2efxKL

#Rheumatology #Proteomics #SjogrensDisease #PrecisionMedicine #HLA #AntibodyReactome #Reactomics

[Infinity Bio Inc. @InfinityBioInc]

New study in @NatureMetabolism uses multi-omics to reveal the molecular drivers of Type 2 Diabetes. By analyzing millions of genetic data points and 1,600+ proteins, researchers found 923 causal genes—85% of which aren't seen in blood. Scale enables discovery!

Read here: https://t.co/CVcD3sQoir

#MultiOmics #Type2Diabetes #PrecisionMedicine #Genomics #Proteomics #GlobalHealth #TranslationalResearch

[Infinity Bio Inc. @InfinityBioInc]

New study in @NatureAging reveals the brain's "neurological clock". Analyzing CSF from 1,000+ individuals, researchers found thousands of proteins linked to aging and disease clusters. Evidence that large-scale multi-omics is key to spotting neurodegeneration decades earlier than clinical symptoms.

Read here: https://t.co/pCRCKWaNoU

#Proteomics #Alzheimers #AgingResearch #Longevity #PrecisionMedicine

[Infinity Bio Inc. @InfinityBioInc]

Precision medicine is powered by large cohorts. By re-analyzing WGS data from ~750k individuals in the UK Biobank and All of Us, researchers linked persistent EBV to chronic diseases like Lupus and dementia. Massive ‘omic’ datasets power these transformative discoveries.

Read here: https://t.co/d8hX9XZ2yQ

#PrecisionMedicine #Biobanks #Genomics #EBV #Biomarkers #Immunology #ChronicIllness #UKBiobank #AllofUs

[Infinity Bio Inc. @InfinityBioInc]

Detecting cancer in vague symptoms is tough. A new study applied proteomics to human cohorts (MEDECA/ALLVOS) and found a 29-protein signature that predicts cancer with an AUC of 0.82. This is a great example of biomarker discovery in real-world clinical scenarios.

Read here: https://t.co/S4e9sljzyT

#CancerResearch #Proteomics #EarlyDetection #PrecisionMedicine #Biomarkers