Ivan Liachko 🇺🇦 @ivanliachko.bsky.social

scientist, father, founder/CEO of @PhaseGenomics; tweets are my own and probably not the position of the company.

[Ivan Liachko 🇺🇦 @ivanliachko.bsky.social @ivanliachko]

Social distancing #PNW style.

[Ivan Liachko 🇺🇦 @ivanliachko.bsky.social @ivanliachko]

It's-a me!

[Phase Genomics @PhaseGenomics]

Catch us at a conference: @ivanliachko takes the stage at @FutureinReview on 6/1 for a panel called “Gut Feeling: Hacking Your Microbiome”.

Later that week, from 6/4 to 6/7, he’ll be on the ground at ASM Microbe 2026 in DC. Say “hey 👋” and connect for the latest in Hi-C!

[Ivan Liachko 🇺🇦 @ivanliachko.bsky.social @ivanliachko]

@baym @mkoeris wait there's an even better one: https://t.co/GdtWCH35pw

[Ivan Liachko 🇺🇦 @ivanliachko.bsky.social @ivanliachko]

@baym @mkoeris

[Phase Genomics @PhaseGenomics]

The biggest sustainability challenges are rooted in biology we’re still learning to understand. Hi-C helps build better genomes and unravel microbial communities that support healthier soils, stronger crops, and more resilient ecosystems. Happy 🌎 Day from Phase Genomics.

[Phase Genomics @PhaseGenomics]

Long reads get you contigs. Proximo™ Hi-C Kits for Plants get you chromosomes you can put to work or meaningful trait / QTL mapping and functional analysis.

Tell us about your research and take 20% off through May 1👇
https://t.co/fLaZA4Fxyb

[Ivan Liachko 🇺🇦 @ivanliachko.bsky.social @ivanliachko]

Chatting with Jeff about their recent oat pangenome paper 🌱🧬. #plants #genome

[Phase Genomics @PhaseGenomics]

One oat line has more structural variation than a panel of wheat lines. That finding, from the 1st chromosome-scale oat assembly, led to a 30-line hexaploid oat pangenome published in @Nature using HiFi+Hi-C.

Full breakdown from senior author Jeff Maughan, PhD, in the clip below

[Ivan Liachko 🇺🇦 @ivanliachko.bsky.social @ivanliachko]

@JasonWilliamsNY @aaas @CSHL kicking @aaas, taking names

[Phase Genomics @PhaseGenomics]

New in the Journal of Water and Health: ProxiMeta™ Hi-C metagenomics improves antimicrobial resistance tracking in wastewater.

Key findings:
→ 2,816 traits detected
→ 554 genes linked to hosts
→ 52.9% of genes were ARGs

🔗https://t.co/ho3k6aGS8L

[Ivan Liachko 🇺🇦 @ivanliachko.bsky.social @ivanliachko]

@ATinyGreenCell Such a great idea, congrats!

[Ivan Liachko 🇺🇦 @ivanliachko.bsky.social @ivanliachko]

@JasonWilliamsNY to be fair, if I see a puppet show displaying from your window, I will def be calling the cops.

[Ivan Liachko 🇺🇦 @ivanliachko.bsky.social @ivanliachko]

@ATinyGreenCell @maxisawesome538

[Phase Genomics @PhaseGenomics]

32% off ProxiMeta™ Hi-C kits ends 3/15 (then save 16% through end of month).

You’ll get:
✅ High-quality MAGs from complex samples
✅ More complete genomes than traditional binning
✅ Accurate host attribution for phages, plasmids, and AMR genes

👉https://t.co/wfDChsFpsF

[Phase Genomics @PhaseGenomics]

March MAGness is here! Score special pricing on ProxiMeta™ Hi-C kits for metagenomics & microbiome studies in everything from complex soil samples, to gut microbiomes, to bioreactors:

🔬 32% off | March 2–15
🔬 16% off | March 16–31

Get started here 👇
https://t.co/wfDChsFpsF

[Phase Genomics @PhaseGenomics]

FISH finds what it's looking for, and only what it's looking for. In a new study in @AjHematologyshows, Hi-C confirmed FISH findings, plus chromothripsis, CN-LOH & complex rearrangements that FISH probes can’t pinpoint.

🔗https://t.co/yZlUPtLXqc

[Phase Genomics @PhaseGenomics]

New Nature Plants study using Proximo™ Hi-C shows how a hybrid eelgrass species inherited low-light tolerance genes from its deep-water parent that could change how we approach coastal restoration.

More from Todd Michael, PhD & team at @salkinstitute 📄 https://t.co/P6eDE6jpOQ

[Phase Genomics @PhaseGenomics]

New Publication in @PLOSBiology : Optimized Hi-C analysis (Z-score filtering) boosts specificity & reveals virus-host interactions using Phase Genomics’ ProxiMeta™ Hi-C: 79 genus-level matches + 293 new linkages in well-studied, climate-critical soils.

https://t.co/TxCPf46utu

[Ivan Liachko 🇺🇦 @ivanliachko.bsky.social @ivanliachko]

@SimonDBarnett unlinked noncomplimentation

[Phase Genomics @PhaseGenomics]

"A year and a half ago, we couldn't have resolved this hybrid genome."

New tech (long reads + Hi-C) let researchers separate parental haplotypes in eelgrass revealing which genes drive low-light tolerance. Todd Michael (@genomeslab) breaks down how:

[Niranjan Nagarajan @NiranjanTW]

Thrilled to share our labor of love over the last 5 years!
Leveraging long-read metagenomics we identified several previously unknown phage families that are highly prevalent in the human gut microbiome. Lead by @hanrong_chen [1/5] https://t.co/O2P0gw8NZO

[Phase Genomics @PhaseGenomics]

Tissue prep drives variability early in Hi-C workflows. A new STAR Protocol adds cryogenic tissue grinding before crosslinking, with safe pause points for optimized lab workflows.

See how it improves reproducibility & library quality ⬇️ https://t.co/fmQ3fSFhVb