Phase Genomics

Blueprints for Biology™: Genomics, Metagenomics, Cytogenomics | ProxiMeta™ Metagenome Deconvolution | Proximo™ Genome Scaffolding | Hi-C Kits |

[Phase Genomics @PhaseGenomics]

Catch us at a conference: @ivanliachko takes the stage at @FutureinReview on 6/1 for a panel called “Gut Feeling: Hacking Your Microbiome”.

Later that week, from 6/4 to 6/7, he’ll be on the ground at ASM Microbe 2026 in DC. Say “hey 👋” and connect for the latest in Hi-C!

[Phase Genomics @PhaseGenomics]

Breeding is supposed to narrow diversity. A new hexaploid oat pangenome in @Nature shows that's not the whole story. HiFi + Hi-C across 30+ lines revealed breeders have been adding structural diversity all along.

Jeff Maughan, PhD, breaks it down in the clip below:

[Phase Genomics @PhaseGenomics]

The biggest sustainability challenges are rooted in biology we’re still learning to understand. Hi-C helps build better genomes and unravel microbial communities that support healthier soils, stronger crops, and more resilient ecosystems. Happy 🌎 Day from Phase Genomics.

[Phase Genomics @PhaseGenomics]

Long reads get you contigs. Proximo™ Hi-C Kits for Plants get you chromosomes you can put to work or meaningful trait / QTL mapping and functional analysis.

Tell us about your research and take 20% off through May 1👇
https://t.co/fLaZA4Fxyb

[Phase Genomics @PhaseGenomics]

One oat line has more structural variation than a panel of wheat lines. That finding, from the 1st chromosome-scale oat assembly, led to a 30-line hexaploid oat pangenome published in @Nature using HiFi+Hi-C.

Full breakdown from senior author Jeff Maughan, PhD, in the clip below

[Phase Genomics @PhaseGenomics]

Your research budget just got a little more room to grow. Take 20% off Proximo™ Hi-C Kits for plant genomics until May 1st.

Hi-C unlocks chromosome-scale insights from your long reads. Get started here 👇
https://t.co/eXCP8ecnSb

[Phase Genomics @PhaseGenomics]

New in the Journal of Water and Health: ProxiMeta™ Hi-C metagenomics improves antimicrobial resistance tracking in wastewater.

Key findings:
→ 2,816 traits detected
→ 554 genes linked to hosts
→ 52.9% of genes were ARGs

🔗https://t.co/ho3k6aGS8L

[Seth Bordenstein @Symbionticism]

From the ⁦@MicrobiomeTimes⁩ Partnership Forum in Copenhagen with colleagues abound including ⁦@evohologen⁩ ⁦@chuttenh⁩ ⁦@PhaseGenomics⁩ ⁦@MortenLimborg⁩ ⁦@SeventureP⁩. The best of the microbiome science applications is here, Wolbachia included!

[Phase Genomics @PhaseGenomics]

32% off ProxiMeta™ Hi-C kits ends 3/15 (then save 16% through end of month).

You’ll get:
✅ High-quality MAGs from complex samples
✅ More complete genomes than traditional binning
✅ Accurate host attribution for phages, plasmids, and AMR genes

👉https://t.co/wfDChsFpsF

[Phase Genomics @PhaseGenomics]

March MAGness is here! Score special pricing on ProxiMeta™ Hi-C kits for metagenomics & microbiome studies in everything from complex soil samples, to gut microbiomes, to bioreactors:

🔬 32% off | March 2–15
🔬 16% off | March 16–31

Get started here 👇
https://t.co/wfDChsFpsF

[Phase Genomics @PhaseGenomics]

FISH finds what it's looking for, and only what it's looking for. In a new study in @AjHematologyshows, Hi-C confirmed FISH findings, plus chromothripsis, CN-LOH & complex rearrangements that FISH probes can’t pinpoint.

🔗https://t.co/yZlUPtLXqc

[Phase Genomics @PhaseGenomics]

New Nature Plants study using Proximo™ Hi-C shows how a hybrid eelgrass species inherited low-light tolerance genes from its deep-water parent that could change how we approach coastal restoration.

More from Todd Michael, PhD & team at @salkinstitute 📄 https://t.co/P6eDE6jpOQ

[Phase Genomics @PhaseGenomics]

New Publication in @PLOSBiology : Optimized Hi-C analysis (Z-score filtering) boosts specificity & reveals virus-host interactions using Phase Genomics’ ProxiMeta™ Hi-C: 79 genus-level matches + 293 new linkages in well-studied, climate-critical soils.

https://t.co/TxCPf46utu

[Phase Genomics @PhaseGenomics]

"A year and a half ago, we couldn't have resolved this hybrid genome."

New tech (long reads + Hi-C) let researchers separate parental haplotypes in eelgrass revealing which genes drive low-light tolerance. Todd Michael (@genomeslab) breaks down how:

[Phase Genomics @PhaseGenomics]

Phase Genomics IRL: a few days together in Portland for real-time collab & creativity. Aligning on new products, pressure-testing ideas, a little fun behind the wheel. It’s how we build even better Hi-C tools for the researchers who rely on them.

A few of our favorite moments👇

[Phase Genomics @PhaseGenomics]

Tissue prep drives variability early in Hi-C workflows. A new STAR Protocol adds cryogenic tissue grinding before crosslinking, with safe pause points for optimized lab workflows.

See how it improves reproducibility & library quality ⬇️ https://t.co/fmQ3fSFhVb

[Nicolas Corradi @Blunt_Microbe]

Combining @PhaseGenomics and @PacBio HiFi allowed acquisition of the complete 🦠genome.
It is composed of 1 chromosome and 2 plasmids, which are mobilome-rich, encoding prophages, an orphan CRISPR array, and complete pathways for many novel and essential cofactors, including heme

[Nicolas Corradi @Blunt_Microbe]

Big congrats to PhD @Ken_M_Mugambi for pulling together this amazing piece of work 🫡

This study details the genome biology of the largest #AMF genome (G. margarita) and its intricate links with its🦠 endosymbiont and 🌱hosts 😀
https://t.co/WIFI2hXfWc

[Phase Genomics @PhaseGenomics]

Wheels up ✈️ Our CEO Ivan’s headed to Newport Beach for Microbes in Wastewater.

He’ll show how ProxiMeta™ links microbes, phages & the mobilome to track #AMR in wastewater. No coding. Just discovery. If you’ll be in Newport for the conference, say hi to @IvanLiachko!

[Phase Genomics @PhaseGenomics]

We heard you. Our 25 in ’25 promo is extended through Jan 16.

Save 25% on Phase Genomics Hi-C kits via direct order, book a complimentary bioinformatics consult, and access discounted full-service ProxiMeta™ packages.

Get started → https://t.co/olqilAr3Yk