"Designing an organic reaction that works in cells is easier than designing a riboswitch". Big Thanks to @LaurelOldach for highlighting our organic chemistry-driven #RNA#biosensing technology in ACS C&EN.
Original article published in @angew_chem https://t.co/YWYGZnlyd3
Researchers have figured out a way to make an RNA biosensor that fluoresces when it encounters small inorganic metabolites—not by engineering the RNA but by adjusting its fluorogenic ligand molecule. https://t.co/XPfWvULFgX #FluorescenceFriday
A Small-Molecule Approach Enables RNA Aptamers to Function as Sensors for Reactive Inorganic Targets (Enver Cagri Izgu and co-workers) @IzguLab#openaccess 🔓 https://t.co/CVAUgfPtIu
Big thanks @RutgersResearch for highlighting our journey to the NIH MIRA! Congratulations to all of the past and present members of the Izgu team @RutgersU! Their hard work has made this recognition possible!
https://t.co/aZm7IqxvJs
Online now: Protocol for building synthetic protocell membranes that sense redox using synthetic phospholipids and natural lipids https://t.co/oWBbxwUomq #protocol#starprotocols#cellpress
Excited to report! Protocell models with synthetic membranes can sense environmental cues important for redox biochemistry and signaling.
By @IzguLab, @AlexSodt et al.
#chembio#materials#lipid#redox#signaling
Enjoy reading! https://t.co/xMmPaiQHtQ
@NShahLab, thanks for your kind invitation to share our lab’s research on bioimaging and biosensing. It was a great pleasure to connect with @Columbia faculty and students!
https://t.co/4ARkwVaRqW
Some "Journals" give you the chance of doubling publication efficiency, how? They invite to submit the articles already published 😮, even if they have a "transparency" statement: “In no case our journal or its editors encourage misconduct”🤔 Fun!
GUVs can use synthetic lipids to sense environmental redox species involved in cell signaling. Our collaborative work with @AlexSodt and Andrew Beaven is out https://t.co/aE5VxsWnFj
doi: 10.26434/chemrxiv-2023-p0nwc-v2
The combined power of organic chemistry and synthetic biology!!! Please check out our new study on how DESIGNER SMALL-MOLECULES can repurpose APTAMERS for detecting unusual INORGANIC targets. @RutgersSAS#sensors#biotech#bacteria
https://t.co/TWQCM4n6cZ
Our preprint (in collaboration w/ Andrew Gow Lab) describes the detection of Nitrative Stress in diverse lipid environments (membranes, ER, and lung) using a novel lipid-based biosensor for peroxynitrite. @RutgersSAS@RutgersChem@RutgersSASMPS
https://t.co/1MyH8GFg0E
@iridium_tea Sorry that I skipped replying. Thanks for asking, they are all safe, but the nation is in peril. We've been organizing initiatives for solidarity and to raise awareness. There will be a vigil at the yard, College Av. at 5 pm/Sunday.
Turkiye / Turkey is experiencing unimaginable levels of devastation due to earthquakes. Your support is needed urgently! Please share the info and donate.
TURKEY EARTHQUAKE FUND
https://t.co/coXcpNrReQ
Our collaborative work, led by the Carman Lab, presents a synthetic proteoliposome platform that mimics the nuclear/ER membrane of yeast. Congrats to Joanna Kwiatek (lead), Bryan Gutierrez, Gil-Soo Han & George Carman! #biology#OrganicChemistry#yeast
https://t.co/SOAyqhXcJT
Our collaborative work, led by the Carman Lab, presents a synthetic proteoliposome platform that mimics the nuclear/ER membrane of yeast. Congrats to Joanna Kwiatek (lead), Bryan Gutierrez, Gil-Soo Han & George Carman! #biology#OrganicChemistry#yeast
https://t.co/SOAyqhXcJT
Pleased to share our recent work with @Khare_Lab and @darrinyork_lbsr "Introducing a New Bond-Forming Activity in an Archaeal DNA Polymerase by Structure-Guided Enzyme Redesign" https://t.co/vVgbjMNHmK