Jacob Insua-Rodríguez

@AvHStiftung postdoctoral fellow @DLawsonlab & @Kessenbrocklab. PhD @DKFZ/@hi_stem_lab. Breast Cancer | Metastasis | Therapy resistance | Single cell genomics

[Jacob Insua-Rodríguez @JInsuaRodriguez]

Why is multi-organ #metastasis so hard to treat? Is it organ ("soil")-specific or is there a #systemic program we’ve missed? 🚨 Our new preprint on @biorxiv_cancer reveals a universal, targetable niche conserved across the body. https://t.co/bKSCFfuWJq 🧵👇

[Jacob Insua-Rodríguez @JInsuaRodriguez]

@JuanCarlosLpz13 @biorxiv_cancer Thanks, Juan Carlos! Glad you enjoyed the read.

[Jacob Insua-Rodríguez @JInsuaRodriguez]

Why is multi-organ #metastasis so hard to treat? Is it organ ("soil")-specific or is there a #systemic program we’ve missed? 🚨 Our new preprint on @biorxiv_cancer reveals a universal, targetable niche conserved across the body. https://t.co/bKSCFfuWJq 🧵👇

[Jacob Insua-Rodríguez @JInsuaRodriguez]

Immensely grateful of this team effort! Thanks to @DLawsonlab & @KessenbrockLab fellows, collaborators at @UCIrvineHealth @UCIMedSchool @UCIrvine @CCBS_UCI, @masrilab, @cholsoon_jang, support from @AvHStiftung; @MetastasisRS, @ASEICAnews; and metastatic breast cancer #patients.

[Jacob Insua-Rodríguez @JInsuaRodriguez]

💊The encouraging news: We can break the circuit. Interference of the MIF-CD74 axis attenuates T cell exhaustion and impairs metastasis systemically. It’s a single target for a multi-organ problem.🎯

[bioRxiv Cancer Bio @biorxiv_cancer]

Single-cell profiling of synchronous multi-organ metastasis reveals a systemic CD74+ lipid-associated macrophage niche driving ... https://t.co/kSkkktFPZc #biorxiv_cancer

[Lucia Borriello @luciaborriell]

🚨 Exciting Opportunity Alert! 🚨

Are you passionate about understanding why cancer patients relapse and uncovering the secrets of tumor dormancy and metastasis?

Join our dynamic lab @templemedschool and @FoxChaseCancer

✨ Please RT to spread the word! ✨

[Jacob Insua-Rodríguez @JInsuaRodriguez]

Check out our latest preprint, where we uncover the pro-metastatic function of PHLDA2, with interesting links to embryonic development. #metastasis @UCIrvine

[Devon Lawson @DLawsonlab]

Check out our new paper identifying the developmental gene PHLDA2 as a robust driver of breast cancer metastasis! Thanks to @PHalasPhD @hannysavage @_DennisMa @KessenbrockLab for all their hard work, and support from @AmericanCancer, @theNCI, & Team Michelle. @UCIMedSchool

[Devon Lawson @DLawsonlab]

Check out our new paper identifying the developmental gene PHLDA2 as a robust driver of breast cancer metastasis! Thanks to @PHalasPhD @hannysavage @_DennisMa @KessenbrockLab for all their hard work, and support from @AmericanCancer, @theNCI, & Team Michelle. @UCIMedSchool

[Paige Halas @PHalasPhD]

Excited to share the preprint of my doctoral work investigating the role of placental development gene PHLDA2 in breast cancer metastasis @DLawsonlab

[Jacob Insua-Rodríguez @JInsuaRodriguez]

@BravoCorderoLab @CUCancerCenter @CUAnschutzGS @CUCancerBio @CUSystem @IcahnMountSinai @TischCancer @TheMarkFdn @morgan_fox_ Enhorabuena, Javier!

[Marisol Soengas @msmelanoma]

If you work in cancer… this is the congress to go, enjoy top notch science and have fun (at a football stadium 😉)
#ASEICACongress
@ASEICAnews

[Marisol Soengas @msmelanoma]

I’m not biased: our first #ASEICAInternational Networking seminar was a success: for the engagement of our speakers (María Alieva, Jacob Insua and @asalboix) and for the many partipants in Spain and abroad.
If you work in cancer and not a member yet, join right away!@ASEICAnews

[Jacob Insua-Rodríguez @JInsuaRodriguez]

It was a pleasure to participate - thanks a lot for the invitation! Looking forward to more events like this. ASEICA-International is a great initiative!

[ASEICA @ASEICAnews]

📍It's time for the I ASEICA-International Networking Seminar:Tumor Microenvironment

1⃣0⃣0⃣participants‼️

✅Cross-disciplinary exchange–From TME to IO, let’s bridge gaps
📢Outstanding speakers:@asalboix (U. of Basel); Jacob Insua(UC Irvine);Maria Alieva (@IIBmCSICUAM)

Thanks!

[ASEICA @ASEICAnews]

📍It's time for the I ASEICA-International Networking Seminar:Tumor Microenvironment

1⃣0⃣0⃣participants‼️

✅Cross-disciplinary exchange–From TME to IO, let’s bridge gaps
📢Outstanding speakers:@asalboix (U. of Basel); Jacob Insua(UC Irvine);Maria Alieva (@IIBmCSICUAM)

Thanks!

[Oskar Marin Bejar @BejarOskar]

Do you want to find future collaborators, a host laboratory to obtain the international PhD mention or strengthen your scientific network? Join #aseicainternational #aseicacomunicacion

[Guillermo de Cárcer @GdC_CCCB_lab]

Ofertamos plaza de Técnico de Laboratorio PEJ-2024-TL/SAL-GL-33015: https://t.co/Da7hiy6okf
Los interesados tienen del 14 al 27 de enero para presentar lassolicitudes. Los aspirantes deberán acceder a la aplicación CONVOCA y seguir los pasos indicados: https://t.co/4mTCL05TVT