Presented at #ASCO26:
Among patients with previously treated metastatic pancreatic ductal adenocarcinoma, the RAS(ON) inhibitor daraxonrasib led to significantly longer overall survival and progression-free survival than chemotherapy. Full phase 3 RASolute 302 trial results: https://t.co/xwLWBZYRzq
@ASCO
My favourite survival curve from the CROWN trial is the transformative impact in CNS control with lorlatinib
Patients with ALK tumors used to have >60% of brain metastasis along their disease. A devastating condition with huge personal, social and economic consequences. Now the risk is nearly over. #LCSM #ASCO26
🔬 El #CSIC es el mayor organismo científico de España, con 124 institutos
👩🔬👨🔬 Sus equipos realizan investigación básica para ampliar las fronteras del conocimiento
Repasa aquí las noticias destacadas de esta #SemanaCSIC 👇📹🧵
📢 Tomorrow at CNB: join us for the seminar ‘Exploring the epidermal stem cell niche’, given by Dr Fiona Watt, Director of @EMBO and internationally recognised leader at @embl (Germany).
📅 29 May
🕛 12:00
📍 CNB Lecture Hall
👉Una nueva estrategia ayuda a reducir la metástasis del melanoma y a mejorar la inmunoterapia en ratones
🔴En modelos preclínicos, bloquear una molécula clave en la metástasis del melanoma reduce la propagación del tumor a otros órganos
🗣️ Héctor Peinado (#CNB@CSIC)
1/2
🚨Excited to share our latest study! 🚨@CNB_CSIC@CNIOStopCancer Thanks to Laura Nogués @CBM_CSIC_UAM and to all collaborators. Targeting NGFR/p75 reduces melanoma metastasis and improves immunotherapy in preclinical models. 👇
https://t.co/CKDgfJgHxM
Groundbreaking results again from @LoweLabMSKCC and his group at @MSKCancerCenter and 28 additional collaborating teams.
Wow!
A convergent uPAR-positive tumor ecosystem creates broad vulnerability to CAR T cell therapy: Cell https://t.co/Zti5v5tETU
“Evolutionary characterization of lung cancer metastasis”. @Nature
501 longitudinally collected primary and metastatic tumour samples from 24 patients with NSCLC.
Impressive. Congrats @SwantonLab, to Jamal-Hanjani lab, @NickyMcGranahan & @ZaccaSimo at @TheCrick@uclcancer
What if the biggest threat in cancer isn’t what’s growing—but what’s waiting? In @NatureRevCancer, Julio Aguirre-Ghiso & colleagues show how dormant cancer cells drive metastasis—and how targeting dormancy could help prevent relapse. https://t.co/rLYn5ozqFZ #CancerResearch
🔬 La Comunidad de Madrid abre una nueva convocatoria de ayudas para startups de investigación científica y tecnológica.
📆 Hasta el 20 de abril.
👉 En la web de @madrimasd.
+Info: https://t.co/SRNR8W9jmA
Recomiendo este Atlas a médicos generales,
familiares,neurólogos,
neurocirujanos,y a todos los profesionales de la salud interesados en el cerebro y las neurociencias.
OCHO https://t.co/4jlRbpXlev
Ayer disfruté mucho dando esta conferencia en la @FundacionAreces sobre el Futuro de la #Dermatología.
Está disponible enterita en https://t.co/qUXlVDyO2Y
El creador Eddie Graf quiso mostrar lo que vive él cuando escucha música. Algo que se llama sinestesia y que permite "ver" la música. Es tremendamente bello.
We developed a single-molecule, multi-modal spatial genomics approach to visualize the structure and function of >100,000 individual extrachromosomal DNA (ecDNA) molecules in their native contexts.
Preprint link at the end of the thread. (1/11)
We’ve trained a multimodal AI model to turn routine pathology slides into spatial proteomics, with the potential to reduce time and cost while expanding access to cancer care.