@CBM_CSIC_UAM Fantastic collaboration with MJ Perez-Alvarez from @UAM_Madrid showing protection against ischemic stroke by genetic partial reprogramming. Published in @Aging_Cell
https://t.co/iUilytrW9A
🧬 Un equipo liderado por Lourdes Ruiz utiliza CRISPR-Cas12a para corregir en el laboratorio el defecto genético causante de la acidemia propiónica, enfermedad rara y potencialmente mortal. El estudio abre opciones a futuras estrategias de terapia génica. https://t.co/1OZNRGk2Vi
🧬 ¿Cómo recupera una célula su identidad después de dividirse? Un estudio liderado por Carlos Perea revela que parte de la cohesina sobrevive a la división celular y ayuda a reactivar los genes que definen la identidad celular.
👉 https://t.co/A0M1UqYTyC
@CSIC@UAM_Madrid
One detail, the rare disease that responds to T+B (BTBGD) coincides with HD, not only in the striatal atrophy, but in the triggering decreased function of the thiamine brain transporter (SLC19A3), mutated in BTBGD and under-expressed in HD)!! Which really sparked the initiative!
https://t.co/3ukKv74nsQ
Thanks, Leora Fox & Rachel Harding @HDBuzzFeed, for the excellent summary of my presentation on the #HUNTIAM clinical trial (Thiamine+Biotin) for Huntington’sdisease, including the evidence that originated it.
@CBM_CSIC_UAM@ehuntingtones@smartinezho1
Back from Boston HD2026 Milton Wexler Meeting. Thanks @hdfcures for organizing it. Excellent science and discussion to advance in the understanding and cure of HD. Very grateful for the opportunity to present our latest work, including promising news from #HUNTIAM clinical trial
🎉 Congratulations to our PI Jorge García Marqués and his team on securing funding from the @FundLejeuneES
Their project will investigate natural mechanisms to reactivate UBE3A, paving the way for new therapeutic strategies for #AngelmanSyndrome
Congratulations! Excellent chacterization of Tau signal in HD brains!
Nice to see follow-up analyses after our original findings by @MartaFernandezN@JR_Cabrera78 at @CBM_CSIC_UAM
¡¡Urgente!!Necesitamos tu apoyo solo faltan unos días. Vota (y Difunde) nuestro proyecto. Ayúdanos a conseguir 5000€ para las familias #Huntington. RT https://t.co/Mg95dJyMjL