Super excited to see this come out! We used the a2,8-sialyltransferase Cst-II to label live cell surfaces with a biotin-linked CMP-Neu5Ac derivative and found some interesting findings along the way! @CCapicciotti#GlycoQueens#ACSChemBiol https://t.co/pDE9ZX0a1o
1/ Thrilled to share an exciting discovery @ ChaoWangBiochem: Reshaping the tumor microenvironment by degrading glycoimmune checkpoints Siglec-7 and -9 #glycotime https://t.co/AJpZSf7JHP
Very excited to share that our work at Paszek Lab has finally been published in Nature Materials! Cancer-associated mucins form nanoscale material barriers that resist attack by immune cells, including natural killer cells and CAR-T cells. #glycotime
https://t.co/Wgz5h8vacg
Super excited to see this come out! We used the a2,8-sialyltransferase Cst-II to label live cell surfaces with a biotin-linked CMP-Neu5Ac derivative and found some interesting findings along the way! @CCapicciotti#GlycoQueens#ACSChemBiol https://t.co/pDE9ZX0a1o
This is my submission for the @aaas and @ScienceMagazine annual Dance Your PhD contest! The title of the dance is ‘The Importance of Multivalency in Siglec Binding of Sialic Acid’, hope you enjoy! https://t.co/58sGNEEp4d #glycotime#glycoqueens
A huge congratulations to @tdotsmvp on the publication of his most recent paper in #ACSchembiol@ACSBioMed, we are really excited about the apparent convergent evolution of these bacterial alkaloid gene clusters https://t.co/DgWUil5Xde
Mini-Me’s for Halloween! 🎃 Great costumes from our #GlycoQueens group. Everyone has imposter syndrome at some point, but maybe I’ll be super productive today!
ICYMI: @JLBabulic & @CCapicciotti@queensu describe a general method for the display of sugar derivatives on cell-surface #glycans. This strategy should shed light on interactions inaccessible by metabolic oligosaccharide engineering.
https://t.co/0QNS8vsliS
#glycotime
Jonathan Babulic @JLBabulic from @queensu talking about precision labeling and photo-crosslinking of glycoconjugates through cell-surface glyco-engineering.
#CGSBanff#glycotime
In 2 Editors' Choice papers, Babulic & Capicciotti @queensu and Kohler & colleagues @UTSWNews@USC report exo-enzymatic strategies for selectively introducing photo-crosslinking probes into cell-surface glycoconjugates.
https://t.co/0QNS8vsliS
https://t.co/ynoTr836m6
#glycotime
@JLBabulic's first paper from our #GlycoQueens group is out! We selectively labelled cell surface N-glycans exo-enzymatically with CMP-Neu5DAz and ST6Gal1, then photo-crosslinked to capture cis-CD22 interactions. #glycotime#proudPI@DbmsTweets https://t.co/yWMg4lR4zi