@JeanGalano@SebVidalChem@AggarwalLab@NatureSynthesis@BristolChem No chance you could do it with that. Would take crazy computing time for something that big and conformationally flexible, not to mention that the error in chemical shifts is likely going to be greater than the biggest chemical shift differences between the diastereomers.
Superconducting magnet engineer chiming in.
This result could be very big news, and overnight revolutionize all of electronics and energy. It might not.
Here's a mental model for the non-expert to understand what's going on.
RTAPS: The good, the bad, and the ugly: 🧵
@NMRspectroscopy Oh right because in the bottom case the top centre is attached to two ethoxy groups so isn’t chiral, but when substituting on the ethoxy, this now makes the centre chiral so the protons are diastereotopic.
@NMRspectroscopy Some kind of tautomerism that’s favoured in one solvent over another? And this tautomerism may break some symmetry in the second case?
More than eight years after a major methyl mercaptan leak at a DuPont plant in La Porte, US killed four employees and injured others, the company and the head of its Insecticide Business Unit have both pleaded guilty to criminal negligence.
https://t.co/sy1wS5syqG
In 2020, Nature endorsed Joe Biden in the US presidential election. A survey finds that viewing the endorsement did not change people’s views of the candidates, but caused some to lose confidence in Nature and in US scientists generally https://t.co/lvrgXmsrl5
@RWMaloneMD Ah yes that super legit paper, which writes equations with Microsoft word, has unlabelled axes on figures, doesn’t reference properly, and literally changes fonts at random throughout the paragraph. Defo a high quality publication.
@stkirsch Hmm, is it common for equations in papers to be formatted with Microsoft word? And to have unlabelled axes in figures? Change font in the middle of a paragraph? This is a lazy attempt at a fake paper.
@BretWeinstein@jordanbpeterson@HeatherEHeying The problem is your camp have claimed a variety of substances are effective against covid, most of the time with very preliminary and inconclusive data. Just because one sticks doesn’t mean that you’ve been right all along, when you’ve been wrong on far more.
Feel free to check out my latest article on antidepressant effectiveness for the Oxford Scientist! Would appreciate any feedback. https://t.co/lEWZZF0atu
The team was able to produce chiral poly(2-vinyl pyridine) from completely achiral 2-vinyl pyridine by electropolymerisation on a magnetic electrode
https://t.co/oz3uID98NI