Jorgo Pata

🔬🦠
Membrane protein and structural biology research#tomographyteam.
PhD at MMSB, Lyon 🇫🇷
Currently Post-doc at the Center for Soft Nanoscience, Münster 🇩🇪

[Jorgo Pata @JPata_]

Using 3DVA of @cryosparc, we were able to image the full conformational landscape after ATP hydrolysis, and propose a function for the ABC signature motif. A big thanks to the authors and especially to my supervisors @Vincent_Chaptal and Pierre Falson!
#CryoEm #membraneproteins

[Jorgo Pata @JPata_]

https://t.co/js8ASXYZIW
Glad to finally share the preprint of my main PhD project on the structure and dynamics of Cdr1. Using CryoEM, we solved different structures, with antifungal drugs, showing the role of this protein in drug resistance phenotypes.

[biorxiv_biochem @biorxiv_biochem]

CryoEM of ATP-driven dynamics and itraconazole binding in a fungal ABC pump https://t.co/TOE6x3Gsbg #biorxiv_biochem

[Jorgo Pata @JPata_]

@NBA Yo, why are refs calling fouls on den only for breathing near OKC players? 😂

[Vincent Chaptal @Vincent_Chaptal]

it's been a long time coming, and 2 fantastic PhD student (@AlexiaGobet and L.Moissonnier) to study the impact on ligands on the conformational spectrum of a multidrug ABC transporter. In the end, we understand how ligands trigger a cooperative ATP-binding

[Jorgo Pata @JPata_]

@EuroLeague You are a bunch of corrupted clowns, tell your shitty referees to open their eyes already, it would help to have a better game.

[Jorgo Pata @JPata_]

@mirkonicolino Benvenuto Caceres!

[Jorgo Pata @JPata_]

@BlondelQ @MBean035 @EuroLeagueFr @ThiasLsf L'application devrait sortir dans 10 jours. Pour l'instant, PAO joue avec les maillots de l'année dernière, les nouveaux seront présentés en décembre apparemment.
Pour l'instant, la vente de maillots passe par un sponsor (https://t.co/j6aCavc8WU), mais pas de livraison en Fr 🤷🏻‍♂️

[Jorgo Pata @JPata_]

Glad to have been part of the Open European Peroxisome Meeting, representing @GatsogiannisLab. And a Best poster prize for the #tomoteam !
#cryoEM #protein #Science

[Jorgo Pata @JPata_]

A really amazing talk from Pr. @yifan_ucsf, a pioneer of the 🔬❄️resolution revolution, and a pleasure to have had him as a guest at @GatsogiannisLab! #cryoEM

[CheMTraP @CheMTraP_MS]

We recently launched our seminar series for the #ChemTrap consortium (Topical Program @uni_muenster) with an amazing talk by @yifan_ucsf @UCSF on the structural studies of TRPV1 channel #cryoEM #resolution_revolution. Stay tuned for more updates!

[Jorgo Pata @JPata_]

Well done to @GatsogiannisLab !!
A cool story and even cooler structures! ❄️🔬

[Gatsogiannis Lab @GatsogiannisLab]

"Ever wondered how α-latrotoxin, the black widow spider's 🕷️ neurotoxin, turns into a cation-selective channel? Check out our latest manuscript! https://t.co/sU3x5ctmv0 @NatureComms #Neuroscience #Toxin #cryoEM @Sfb1348 @uni_muenster

[Gatsogiannis Lab @GatsogiannisLab]

📢New lab preprint: 2.05 A #cryoEM structure of UapA: unprecedented aspects of the elevator-type transport (incl. water, lipids) and regulatory roles of the N-tail. With Diallinas, Mikros labs. Kudos @broutzakis and all co-authors. @uni_muenster #SoN
https://t.co/XzGOSkbNg4

[TrashTalk @TrashTalk_fr]

Céline Dion qui chante sur la Tour Eiffel, à jamais dans les souvenirs 🥹❤️ https://t.co/mYUrvuNgAJ

[Jorgo Pata @JPata_]

@FFLose Après PhiPhi, la seule alternative possible !!

[Jorgo Pata @JPata_]

@B_H006 @EuroLeagueFr @EuroLeague @skweektv @paobcgr En vrai le budget est moindre que celui du Real, Barca etc 🤷🏼‍♂️ et il a commencé à investir car il a eu le palais (OAKA) pour Panathinaikos, ce qui lui ramène une énorme quantité. Faut ajouter les différents sponsors (2 mln/an juste pour le nom de l'équipe) etc

[Jorgo Pata @JPata_]

@mirkonicolino Del Piero in società!!

[Jorgo Pata @JPata_]

@NIKOS6ASTEROS Τελικά καλά το είχα δει, απλά όι τύποι είνα�� επικίνδυνοι και σφυρίζουν ότι θέλουν.

[Jorgo Pata @JPata_]

@TheHoopCentral Just get rid of that b*um, he is hurting the team

[Jorgo Pata @JPata_]

@FFLose Papagiannis, 13ème choix, un bon physique 😅 et un gros flop finalement.

[Vincent Chaptal @Vincent_Chaptal]

With the team in front of the new CM02 microscope. Thanks for the private tour @SchoehnGuy and Lefteris. Can't wait to use the new toy!