@DrKennyYu_Neuro Dear Dr. Yu, fascinating work, this aligns well with my glioblastoma research experience. I have sent you a DM and would appreciate your time.
This is Mariano Barbacid, a Spanish cancer researcher who recently made the news after finding a cure for an aggressive form of pancreatic cancer in mice. His lab developed a new triple therapy regimen targeting the KRAS cancer pathway, implicated in 90% of pancreatic cancers. The combination of daraxonsib, a RAS(ON) inhibitor, afatinib (EGFR/HER2 inhibitor) and SD36 (a selective STAT3 PROTAC) led to complete elimination of tumour cells over a 200 day study period, bringing much needed hope to this often devastating condition.
🇪🇸 A research team led by Spanish oncologist Mariano Barbacid has successfully eradicated pancreatic cancer in mice for the first time, offering hope for a human cure.
The experiment involved treating the mice by combining three low-toxicity drugs, according to a study published today.
Dr. Barbacid has made a number of high profile discoveries in medical science, with his National Cancer Research Centre in Spain becoming one of the world's leading centres of cancer research.
Pancreatic cancer is one of the most aggressive cancers, with the variant treated having a five-year survival rate of less than 5%.
Clinical trials will begin soon, followed by approval for use of this treatment in humans.
Follow: @europa
Spanish oncologist Mariano Barbacid's team achieved complete elimination of KRAS-mutated pancreatic tumors in mice using a low-toxicity trio of drugs (gemcitabine, ATRA, and neratinib), as detailed in a January 27, 2026, PNAS study.
A severed nerve doesn't have to mean permanent loss of function.
This patient accidentally cut their median nerve. To fix it, we performed a cable graft—essentially building a bridge for the nerve fibers to grow across and reconnect.
This is the reconstruction side of #PlasticSurgery restoring form AND function ⚡️🔌
#MedTwitter #Surgery #HandSurgery #Reconstruction #Nerve
Make this your must read for the day. We need to celebrate doctors like her.
This is the story of Dr. Sivaranjani Santosh, a paediatrician from Hyderabad, who fought for 8 years against sugar-rich drinks falsely marketed as ORS.
Her persistence led to FSSAI’s landmark order, protecting children and patients from misleading claims.
“These drinks had 10x the sugar WHO recommends, worsening diarrhoea and complications in millions of kids,” she explains.
Her 8-year battle changed the game for public health and children across India.
What is sad is that it took 8 years for the government and regulator to understand that these so-called ORS drinks were harmful to children. We need to have quicker public health reforms.
@RADIS_lab@vitorpereiracan Could you please share the details on how I can apply for an internship with the RADIS lab, as I am interested in your research?
Respected @naralokesh garu #beggarfreeAP act is all what we need and under this act old aged beggars should be under NGOs or other gov organizations,provide skills to those who are capable of working and finally children should be given education in government schools.
I humbly request you to take decisive action to address this issue and consider introducing a comprehensive policy to dismantle this mafia and protect vulnerable children. Your leadership in this matter can bring meaningful change and hope to many lives.
Thank you
@OfficeofNL
Respected @naralokesh Sir,
The exploitation of children by the beggar mafia is a grave concern that needs urgent attention. While helping one child is commendable, countless others continue to suffer in silence under this inhumane system. Contd..
This is heartbreaking. Every child deserves safety, love, and dignity. We will locate this child and ensure he receives the protection and care he needs. Those responsible for abusing him will be held accountable.
@OfficeofNL